Annotations: 6C2S

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	MarR	e6c2sA1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: MarR	ECOD (1.6)
C [auth B]	MarR	e6c2sB1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: MarR	ECOD (1.6)
E [auth C]	MarR	e6c2sC1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: MarR	ECOD (1.6)
G [auth D]	MarR	e6c2sD1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: MarR	ECOD (1.6)

Chains	Accession	Name	Description	Comments	Source
A, C [auth B], E [auth C], G [auth D]	PF01047	MarR family (MarR)	MarR family	The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is ...	The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds [1]. The structure of MarR is known [2] and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C [auth B], E [auth C], G [auth D]	Transcriptional regulator, MarR family	transcription regulator activity DNA-binding transcription factor activity	response to stimulus response to stress	-
B [auth U], F [auth X]	23-mer	-	-	-
D [auth V], H [auth Y]	23-mer	-	-	-

Chains	Accession	Name	Type
A, C [auth B], E [auth C], G [auth D]	IPR000835	MarR-type HTH domain	Domain
A, C [auth B], E [auth C], G [auth D]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
A, C [auth B], E [auth C], G [auth D]	IPR039422	Transcription regulators MarR/SlyA-like	Family
A, C [auth B], E [auth C], G [auth D]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily