7DRK

Crystal structure of phosphatidylglycerol phosphate synthase in complex with cytidine diphosphate-diacylglycerol

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CDP-OH_P_transf	e7drkA1	A: alpha bundles	X: CDP-alcohol phosphotransferase helical bundle domain (From Topology)	H: CDP-alcohol phosphotransferase helical bundle domain (From Topology)	T: CDP-alcohol phosphotransferase helical bundle domain	F: CDP-OH_P_transf	ECOD (1.6)
B	CDP-OH_P_transf	e7drkB1	A: alpha bundles	X: CDP-alcohol phosphotransferase helical bundle domain (From Topology)	H: CDP-alcohol phosphotransferase helical bundle domain (From Topology)	T: CDP-alcohol phosphotransferase helical bundle domain	F: CDP-OH_P_transf	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.120.1760	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	CDP-alcohol phosphotransferase transmembrane (TM) domain	CATH (utative)
B	1.20.120.1760	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	CDP-alcohol phosphotransferase transmembrane (TM) domain	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01066	CDP-alcohol phosphatidyltransferase (CDP-OH_P_transf)	CDP-alcohol phosphatidyltransferase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity CDP-alcohol phosphatidyltransferase activity transferase activity catalytic activity phosphotransferase activity, for other substituted phosphate groups transferase activity, transferring phosphorus-containing groups	phosphatidylglycerol metabolic process glycerophospholipid biosynthetic process glycerophospholipid metabolic process lipid biosynthetic process primary metabolic process phospholipid biosynthetic process phospholipid metabolic process biosynthetic process glycerolipid biosynthetic process phosphatidylglycerol biosynthetic process organophosphate metabolic process organophosphate biosynthetic process phosphate-containing compound metabolic process glycerolipid metabolic process phosphatidylglycerol metabolic process glycerophospholipid biosynthetic process glycerophospholipid metabolic process lipid biosynthetic process primary metabolic process phospholipid biosynthetic process phospholipid metabolic process biosynthetic process glycerolipid biosynthetic process phosphatidylglycerol biosynthetic process organophosphate metabolic process organophosphate biosynthetic process phosphate-containing compound metabolic process glycerolipid metabolic process metabolic process cellular process phosphorus metabolic process lipid metabolic process	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR043130	CDP-alcohol phosphatidyltransferase, transmembrane domain	Homologous Superfamily
A, B	IPR048254	CDP-alcohol phosphatidyltransferase, conserved site	Conserved Site
A, B	IPR004570	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	Family
A, B	IPR050324	CDP-alcohol phosphatidyltransferase class-I	Family
A, B	IPR000462	CDP-alcohol phosphatidyltransferase	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B	OPM	Transmembrane	Alpha-helical polytopic	Choline/ethanolamine phosphotransferase	Choline/ethanolamine phosphotransferase 1

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Phospholipid Synthases	PgsA phosphatidylinositol phosphate synthase in complex with phosphatidylglycerol phosphate

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.