8CGV | pdb_00008cgv

Tiamulin bound to the 50S subunit


Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
A [auth 0]SCOP2B SuperfamilyZn-binding ribosomal proteins 8096362 3001320 SCOP2B (2022-06-29)
C [auth 2]SCOP2B SuperfamilyL35p-like 8035388 3000790 SCOP2B (2022-06-29)
D [auth 3]SCOP2B SuperfamilyRibosomal protein L36 8035391 3001346 SCOP2B (2022-06-29)
G [auth c]SCOP2B SuperfamilyTranslation proteins SH3-like KOW motif containing domain 8035393 3000334 SCOP2B (2022-06-29)
G [auth c]SCOP2B SuperfamilyNucleic acid-binding proteins 8035394 3000135 SCOP2B (2022-06-29)
J [auth g]SCOP2B SuperfamilyRibosomal protein L6 8035398 3000724 SCOP2B (2022-06-29)
J [auth g]SCOP2B SuperfamilyRibosomal protein L6 8035397 3000724 SCOP2B (2022-06-29)
L [auth i]SCOP2B SuperfamilyRibosomal protein L13 8096350 3001134 SCOP2B (2022-06-29)
M [auth j]SCOP2B Superfamily50S Ribosomal protein L14-like 8103358 3000433 SCOP2B (2022-06-29)
N [auth k]SCOP2B SuperfamilyRibosomal proteins L15p and L18e 8070553 3001045 SCOP2B (2022-06-29)
P [auth m]SCOP2B SuperfamilyProkaryotic ribosomal protein L17 8035409 3000995 SCOP2B (2022-06-29)
R [auth o]SCOP2B SuperfamilyTranslation proteins SH3-like KOW motif containing domain 8096364 3000334 SCOP2B (2022-06-29)
T [auth q]SCOP2B Superfamilyl21p-like 8096354 3002005 SCOP2B (2022-06-29)
U [auth r]SCOP2B SuperfamilyRibosomal protein L22 8096336 3001078 SCOP2B (2022-06-29)
V [auth s]SCOP2B SuperfamilyRibosomal proteins S24e, L23 and L15e 8035415 3000210 SCOP2B (2022-06-29)
W [auth t]SCOP2B SuperfamilyTranslation proteins SH3-like KOW motif containing domain 8096358 3000334 SCOP2B (2022-06-29)
Y [auth v]SCOP2B SuperfamilyRibosomal L27 protein-like 8096338 3000539 SCOP2B (2022-06-29)
Z [auth w]SCOP2B SuperfamilyL28p-like 8035424 3001966 SCOP2B (2022-06-29)
AA [auth x]SCOP2B SuperfamilyRibosomal protein L29 (L29p) 8096370 3000713 SCOP2B (2022-06-29)
BA [auth y]SCOP2B SuperfamilyRibosomal protein L30p/L7e 8096372 3001378 SCOP2B (2022-06-29)
CA [auth z]SCOP2B SuperfamilyZn-binding ribosomal proteins 8096380 3001320 SCOP2B (2022-06-29)
O [auth l]SCOP2B SuperfamilyRibosomal protein L16p/L10e 8096366 3000884 SCOP2B (2022-06-29)
S [auth p]SCOP2B SuperfamilyRibosomal protein L20 8096382 3000563 SCOP2B (2022-06-29)
X [auth u]SCOP2B SuperfamilyRibosomal protein L25-like 8042538 3001161 SCOP2B (2022-06-29)
H [auth d]SCOP2B SuperfamilyTranslational proteins 8032955 3000811 SCOP2B (2022-06-29)
I [auth e]SCOP2B SuperfamilyRibosomal protein L4 8096356 3001146 SCOP2B (2022-06-29)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
J [auth g]3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A domain 3CATH (utative)
N [auth k]3.100.10.10 Alpha Beta Ribosomal Protein L15 Chain: K domain 2CATH (utative)
U [auth r]3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22 Chain ACATH (utative)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth 0]PF00471Ribosomal protein L33 (Ribosomal_L33)Ribosomal protein L33- Family
B [auth 1]PF00468Ribosomal protein L34 (Ribosomal_L34)Ribosomal protein L34- Family
C [auth 2]PF01632Ribosomal protein L35 (Ribosomal_L35p)Ribosomal protein L35- Family
D [auth 3]PF00444Ribosomal protein L36 (Ribosomal_L36)Ribosomal protein L36Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth 0]Large ribosomal subunit protein bL33
B [auth 1]Large ribosomal subunit protein bL34
C [auth 2]Large ribosomal subunit protein bL35
D [auth 3]Large ribosomal subunit protein bL36A
G [auth c]Large ribosomal subunit protein uL2
J [auth g]Large ribosomal subunit protein uL6
K [auth h]Large ribosomal subunit protein bL9
L [auth i]Large ribosomal subunit protein uL13
M [auth j]Large ribosomal subunit protein uL14
N [auth k]50S ribosomal protein L15
P [auth m]Large ribosomal subunit protein bL17
Q [auth n]Large ribosomal subunit protein uL18
R [auth o]Large ribosomal subunit protein bL19
T [auth q]Large ribosomal subunit protein bL21
U [auth r]Large ribosomal subunit protein uL22
V [auth s]Large ribosomal subunit protein uL23
W [auth t]Large ribosomal subunit protein uL24
Y [auth v]Large ribosomal subunit protein bL27
Z [auth w]Large ribosomal subunit protein bL28
AA [auth x]Large ribosomal subunit protein uL29
BA [auth y]Large ribosomal subunit protein uL30
CA [auth z]Large ribosomal subunit protein bL32
O [auth l]Large ribosomal subunit protein uL16
S [auth p]Large ribosomal subunit protein bL20
X [auth u]50S ribosomal protein L25
E [auth a]23S rRNA---
F [auth b]5S rRNA---
H [auth d]Large ribosomal subunit protein uL3
I [auth e]Large ribosomal subunit protein uL4

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A [auth 0]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
A [auth 0]IPR038584Large ribosomal subunit protein bL33 superfamilyHomologous Superfamily
A [auth 0]IPR001705Large ribosomal subunit protein bL33Family
A [auth 0]IPR018264Large ribosomal subunit protein bL33, conserved siteConserved Site
B [auth 1]IPR020939Large ribosomal subunit protein bL34, conserved siteConserved Site
B [auth 1]IPR000271Large ribosomal subunit protein bL34Family
C [auth 2]IPR021137Large ribosomal subunit protein bL35-likeFamily
C [auth 2]IPR018265Large ribosomal subunit protein bL35, conserved siteConserved Site
C [auth 2]IPR001706Large ribosomal subunit protein bL35Family
C [auth 2]IPR037229Large ribosomal subunit protein bL35 superfamilyHomologous Superfamily
D [auth 3]IPR000473Large ribosomal subunit protein bL36Family
D [auth 3]IPR035977Large ribosomal subunit protein bL36 superfamilyHomologous Superfamily
G [auth c]IPR022669Large ribosomal subunit protein uL2, C-terminalDomain
G [auth c]IPR014722Large ribosomal subunit protein uL2, domain 2Homologous Superfamily
G [auth c]IPR008991Translation protein SH3-like domain superfamilyHomologous Superfamily
G [auth c]IPR022671Large ribosomal subunit protein uL2, conserved siteConserved Site
G [auth c]IPR005880Large ribosomal subunit protein uL2, bacterial/organellar-typeFamily
G [auth c]IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
G [auth c]IPR022666Large ribosomal subunit protein uL2, RNA-binding domainDomain
G [auth c]IPR014726Large ribosomal subunit protein uL2, domain 3Homologous Superfamily
G [auth c]IPR002171Large ribosomal subunit protein uL2Family
J [auth g]IPR036789Large ribosomal subunit protein uL6-like, alpha-beta domain superfamilyHomologous Superfamily
J [auth g]IPR019906Large ribosomal subunit protein uL6, bacterial-typeFamily
J [auth g]IPR020040Large ribosomal subunit protein uL6, alpha-beta domainDomain
J [auth g]IPR000702Large ribosomal subunit protein uL6-likeFamily
J [auth g]IPR002358Large ribosomal subunit protein uL6, conserved siteConserved Site
K [auth h]IPR036935Large ribosomal subunit protein bL9, N-terminal domain superfamilyHomologous Superfamily
K [auth h]IPR020069Large ribosomal subunit protein bL9, C-terminalDomain
K [auth h]IPR020070Large ribosomal subunit protein bL9, N-terminalDomain
K [auth h]IPR009027Large ribosomal subunit protein bL9/RNase H1, N-terminalHomologous Superfamily
K [auth h]IPR020594Large ribosomal subunit protein bL9, bacteria/chloroplastFamily
K [auth h]IPR036791Large ribosomal subunit protein bL9, C-terminal domain superfamilyHomologous Superfamily
K [auth h]IPR000244Large ribosomal subunit protein bL9Family
L [auth i]IPR023563Large ribosomal subunit protein uL13, conserved siteConserved Site
L [auth i]IPR005822Large ribosomal subunit protein uL13Family
L [auth i]IPR036899Large ribosomal subunit protein uL13 superfamilyHomologous Superfamily
L [auth i]IPR005823Large ribosomal subunit protein uL13, bacterial-typeFamily
M [auth j]IPR005745Large ribosomal subunit protein uL14, bacterial-typeFamily
M [auth j]IPR036853Large ribosomal subunit protein uL14 superfamilyHomologous Superfamily
M [auth j]IPR000218Large ribosomal subunit protein uL14Family
M [auth j]IPR019972Large ribosomal subunit protein uL14, conserved siteConserved Site
N [auth k]IPR005749Large ribosomal subunit protein uL15, bacterial-typeFamily
N [auth k]IPR021131Large ribosomal subunit protein uL15/eL18Domain
N [auth k]IPR030878Large ribosomal subunit protein uL15Family
N [auth k]IPR001196Large ribosomal subunit protein uL15, conserved siteConserved Site
N [auth k]IPR036227Large ribosomal subunit protein uL15/eL18 superfamilyHomologous Superfamily
P [auth m]IPR036373Large ribosomal subunit protein bL17 superfamilyHomologous Superfamily
P [auth m]IPR047859Large ribosomal subunit protein bL17, conserved siteConserved Site
P [auth m]IPR000456Large ribosomal subunit protein bL17Family
Q [auth n]IPR005484Large ribosomal subunit protein uL18, bacterial/plantae/animaliaFamily
Q [auth n]IPR004389Large ribosomal subunit protein uL18, bacterial-typeFamily
R [auth o]IPR001857Large ribosomal subunit protein bL19Family
R [auth o]IPR038657Large ribosomal subunit protein bL19 superfamilyHomologous Superfamily
R [auth o]IPR018257Large ribosomal subunit protein bL19, conserved siteConserved Site
R [auth o]IPR008991Translation protein SH3-like domain superfamilyHomologous Superfamily
T [auth q]IPR028909Large ribosomal subunit protein bL21-likeFamily
T [auth q]IPR001787Large ribosomal subunit protein bL21Family
T [auth q]IPR036164Large ribosomal subunit protein bL21-like superfamilyHomologous Superfamily
T [auth q]IPR018258Large ribosomal subunit protein bL21, conserved siteConserved Site
U [auth r]IPR047867Large ribosomal subunit protein uL22, bacterial/organelle-typeFamily
U [auth r]IPR036394Ribosomal protein uL22 superfamilyHomologous Superfamily
U [auth r]IPR001063Large ribosomal subunit protein uL22Family
U [auth r]IPR018260Large ribosomal subunit protein uL22, conserved siteConserved Site
U [auth r]IPR005727Large ribosomal subunit protein uL22, bacterial/chloroplast-typeFamily
V [auth s]IPR012678Ribosomal protein uL23/eL15/eS24 core domain superfamilyHomologous Superfamily
V [auth s]IPR012677Nucleotide-binding alpha-beta plait domain superfamilyHomologous Superfamily
V [auth s]IPR001014Large ribosomal subunit protein uL23, conserved siteConserved Site
V [auth s]IPR013025Large ribosomal subunit protein uL23-likeFamily
W [auth t]IPR014722Large ribosomal subunit protein uL2, domain 2Homologous Superfamily
W [auth t]IPR008991Translation protein SH3-like domain superfamilyHomologous Superfamily
W [auth t]IPR003256Large ribosomal subunit protein uL24Family
W [auth t]IPR041988Large ribosomal subunit protein uL24, KOW domainDomain
W [auth t]IPR005824KOWDomain
W [auth t]IPR005825Large ribosomal subunit protein uL24, conserved siteConserved Site
Y [auth v]IPR001684Large ribosomal subunit protein bL27Family
Y [auth v]IPR018261Large ribosomal subunit protein bL27, conserved siteConserved Site
Z [auth w]IPR001383Large ribosomal subunit protein bL28, bacterial-typeFamily
Z [auth w]IPR037147Large ribosomal subunit protein bL28 superfamilyHomologous Superfamily
Z [auth w]IPR026569Large ribosomal subunit protein bL28Family
Z [auth w]IPR034704Large ribosomal subunit protein bL28/bL31-like superfamilyHomologous Superfamily
AA [auth x]IPR050063Universal ribosomal protein uL29Family
AA [auth x]IPR001854Large ribosomal subunit protein uL29Family
AA [auth x]IPR036049Large ribosomal subunit protein uL29 superfamilyHomologous Superfamily
AA [auth x]IPR018254Large ribosomal subunit protein uL29, conserved siteConserved Site
BA [auth y]IPR036919Large ribosomal subunit protein uL30, ferredoxin-like fold domain superfamilyHomologous Superfamily
BA [auth y]IPR005996Large ribosomal subunit protein uL30, bacterial-typeFamily
BA [auth y]IPR016082Large ribosomal subunit protein uL30-like, ferredoxin-like fold domainDomain
BA [auth y]IPR018038Large ribosomal subunit protein uL30, conserved siteConserved Site
CA [auth z]IPR002677Large ribosomal subunit protein bL32Family
CA [auth z]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
CA [auth z]IPR044957Large ribosomal subunit protein bL32, bacterial typeFamily
O [auth l]IPR036920Large ribosomal subunit protein uL16 superfamilyHomologous Superfamily
O [auth l]IPR020798Large ribosomal subunit protein uL16, conserved siteConserved Site
O [auth l]IPR000114Large ribosomal subunit protein uL16, bacterial-typeFamily
O [auth l]IPR016180Large ribosomal subunit protein uL16 domainDomain
O [auth l]IPR047873Large ribosomal subunit protein uL16Family
S [auth p]IPR049946Large ribosomal subunit protein bL20, conserved siteConserved Site
S [auth p]IPR035566Ribosomal protein bL20, C-terminalHomologous Superfamily
S [auth p]IPR005813Large ribosomal subunit protein bL20Family
X [auth u]IPR020055Ribosomal protein bL25, short-formFamily
X [auth u]IPR029751Large ribosomal subunit protein bL25, L25 domainDomain
X [auth u]IPR020056Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminalHomologous Superfamily
X [auth u]IPR011035Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamilyHomologous Superfamily
X [auth u]IPR050070Bact_ribosom_prot_bL25Unknown
H [auth d]IPR019926Large ribosomal subunit protein uL3, conserved siteConserved Site
H [auth d]IPR019927Large ribosomal subunit protein uL3, bacterial/organelle-typeFamily
H [auth d]IPR009000Translation protein, beta-barrel domain superfamilyHomologous Superfamily
H [auth d]IPR000597Large ribosomal subunit protein uL3Family
I [auth e]IPR013005Large ribosomal subunit protein uL4-likeFamily
I [auth e]IPR002136Large ribosomal subunit protein uL4Family
I [auth e]IPR023574Large ribosomal subunit protein uL4 domain superfamilyHomologous Superfamily

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
O [auth l]4D4 Parent Component: ARG

O [auth l]MS6
E [auth a]1MG Parent Component: G

E [auth a]2MA Parent Component: A

E [auth a]2MG Parent Component: G

E [auth a]3TD Parent Component: U

E [auth a]5MC Parent Component: C

E [auth a]5MU Parent Component: U

E [auth a]6MZ Parent Component: A

E [auth a]G7M Parent Component: G

E [auth a]H2U Parent Component: U

E [auth a]OMC Parent Component: C

E [auth a]OMG Parent Component: G

E [auth a]OMU Parent Component: U

E [auth a]PSU Parent Component: U

H [auth d]MEQ Parent Component: GLN

RESIDAA0071

PSI-MOD :  N5-methyl-L-glutamine MOD:00080
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