Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent.[L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986.[L31858]
Synonyms
Acidum tranexamicum
ácido tranexámico
trans-Amcha
Acide tranéxamique
Tranexmic acid
Tranhexamic acid
trans-Tranexamic acid
Tranexamic acid
Trans AMCHA
trans-4-aminomethylcyclohexane-1-carboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
Tranexamsaeure
Brand Names
Tranexamic Acid In Sodium Chloride
Pure Whitenol Serum
Tranexamic Acid
Tranexamic Acid Injection BP
Cyklokapron 100 mg/ml
Cyklokapron
Erfa-tranexamic
Tranexamic Acid Injection
Tranexamic Acid Tablets
Lysteda
SKINMD LABORATORIES ReviTox blue
Tranexamic Acid Injection, USP
Skinmd Laboratories Pure Whitenol Intensive
Cyklokapron 500 mg
Tranexamic acid
Mar-tranexamic Acid
Gd-tranexamic Acid
Skinmd Laboratories Pure Whitenol Serum
Liquid
M-tranexamic Acid
Indication
Taken orally, tranexamic acid is indicated for the treatment of hereditary angioedema,[L31883] cyclic heavy menstrual bleeding in premenopausal females,[L31858] and other instances of significant bleeding in the context of hyperfibrinolysis.[L31883] Given intravenously, tranexamic acid is indicated for short-term use (2-8 days) in patients with hemophilia to prevent or reduce bleeding following tooth extraction.[L31853]
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
