RCO

RESORCINOL

Created:	1999-07-08
Last modified:	2020-06-05

Find Related PDB Entry
19 entries where RCO is found as a standalone ligand

Help Find related ligands:
Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Help

Find related ligands:

Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Chemical Details
Formal Charge	0
Atom Count	14
Chiral Atom Count	0
Bond Count	14
Aromatic Bond Count	6

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	RESORCINOL
Synonyms	1,3-BENZENEDIOL; 1,3-DIHYDROXYBENZENE
Systematic Name (OpenEye OEToolkits)	benzene-1,3-diol
Formula	C₆ H₆ O₂
Molecular Weight	110.111
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	Oc1cccc(O)c1
SMILES	CACTVS	3.341	Oc1cccc(O)c1
SMILES	OpenEye OEToolkits	1.5.0	c1cc(cc(c1)O)O
Canonical SMILES	CACTVS	3.341	Oc1cccc(O)c1
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1cc(cc(c1)O)O
InChI	InChI	1.03	InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H
InChIKey	InChI	1.03	GHMLBKRAJCXXBS-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB11085 ?
Name	Resorcinol
Groups	approved
Description	Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works by helping to remove hard, scaly, or roughened skin. Although it is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of formal therapeutic indication.
Synonyms	1,3-Benzenediol m-hydroxyphenol 1,3-Dihydroxybenzol m-Hydroquinone Resorcinol 1,3-Dihydroxybenzene Resorzin
Brand Names	Quality Choice Vaginal Anti-Itch Maximum Strength Utiliderm Acne Control Tinted Acne Treatment VAGISIL Anti-Itch Creme Regular Strength Maximum Strength Feminine Anti-Itch Family Wellness Good Sense Vagicaine Anti Itch Vagi-cure (maximum Strength) Vagicaine Maximum Strength Cvs Acne Treatment Well at Walgreens Anti-Itch Maximum Strength Mazon Medicated Cream DG Health Feminine Anti-itch Clearasil Daily Clear Adult Tinted Acne Treatment Glytone acne treatment flesh tinted acne Acne Drying Topical Benzal Vagisil Creme Regular Strength Topcare Vagicaine Up and up vagicaine VAGISIL Anti-Itch Medicated Creme Regular Strength Anti Itch Vagicaine Acne Treatment maximum strength CVS Adult Acnomel Leader Anti-Itch Maximum Strength Jon Ares Acne Control Mild OptimV Anti-Itch Maximum Strength Leader Regular Strength Anti-Itch Clearasil Daily Clear Tinted Adult Treatment Mirakel Leader Maximum Strength Anti-Itch Leader Anti-Itch Regular Strength Good Neighbor Pharmacy Vagicaine VAGISIL Anti-Itch Medicated Creme Maximum Strength Signature Care Vagicaine Thunas Eczema Ont Anti-Itch Medicated Maximum Strength Basic Care Vagicaine Glytone acne Feminine Anti-Itch Creme Anti-Itch Regular Strength Equaline Vagicaine Maximum Strength Glytone Acne Spot Treatment Rezamid Acne Aid Gel Assured Feminine Anti-itch Meijer Maximum Strength Vagicaine Rite Aid Original Strength Vagicaine Vagicaine Medicated Maximum Strength Clearasil Skin Tone Acne Crm Medication Rexall Feminine Maximum Strength Anti-itch Vagicaine Maximum Strength Anti-Itch Cream Vagisil Anti Itch Maximum Strength Eau Resolutive Soker Clarifying Mask Family Wellness Resinol Acnomel Skin Tone Cream Adult Acnomel Tinted Budpak Feminine Anti-Itch Equate vagicaine maximum strength Clearasil Vanishing Acne Crm Medication BENZOCAINE and RESORCINOL Image Essentials Vagicaine Clearskin 2 Tinted Blemish Crm Vagisil Anti Itch Original Strength Hemo-pic Mirakel Pain and Itch Relief Acnotex acne Treatment Smart Sense Vagicaine Maximum Strength
Indication	Contemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L40069, F61] or as topical antibacterial skin treatment products for conditions like acne, seborrheic dermatitis, eczema, and others [L2746, L2745, L2744, L40069, F61].
Categories	Anti-Acne Preparations Anti-Acne Preparations for Topical Use Anti-Infective Agents Anti-Infective Agents, Local Benzene Derivatives Dermatologicals Drugs that are Mainly Renally Excreted Ophthalmologicals Phenols Root Canal Filling Materials Sensory Organs
ATC-Code	D10AX02 S01AX06
CAS number	108-46-3

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Carbonic anhydrase 12	MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSC...	unknown	inhibitor
Carbonic anhydrase 2	MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS...	unknown	inhibitor
Carbonic anhydrase 14	MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDI...	unknown	inhibitor
Prostaglandin G/H synthase 1	MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...	unknown	inhibitor
Thyroid peroxidase	MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLV...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	5054
ChEMBL	CHEMBL24147
ChEBI	CHEBI:27810
CCDC/CSD	GAJROB, HOLKAW, IGIZEG01, KAJFEJ, IGIZAC, ACOYOG01, EDAZOB, EDAYIU, ABEKUN03, ABEKUN02, ABELAU06, ABEKUN04, HOPKED, IGIZEG, ABEKUN01, DUVHAE01, ACOYOG, DEGQUE, ABELAU03, ABELAU02, ABELAU01, EJIXUQ, DOGCIO, ABELAU04, EBIMIM, ABELAU05, BODSAO, KIHZAD, ANUNED, GAVBAI, KEXHUR, FOSFOK, AXEZIM, ABEKUN, KEXJIH, ABELAU, DUVHAE, JORBEA, COZZUN, ABELIC, ASORIL, ITUJOX, AXOGIE, GIHBUW, CEKBOJ, BULLAX, KIJLAS, IMIWAF, IYAZEQ