VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152 ?
Name	Thiamine
Groups	nutraceutical approved vet_approved investigational
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	thiaminium Antiberiberi factor Thiamine mononitrate Aneurin thiamine(1+) Thiamin thiamine(1+) ion Tiamina Thiamine Vitamin B1 Thiaminum Thiamine chloride Thiamine hydrochloride
Brand Names	Alsimine W Vitamins A D Iberet 500 Corvita Nutrifer Plus Tablets Tricare Prenatal DHA One One Daily Vitamin and Mineral Dietary Supplement B 6 Plus Ribotin-E Insur-all Vitamin Supplement Vinacal Women's Change Formula Vitamin B1 100 mg B Complex W Vit C W Non-med Yeast&liver Tab B Complex 50+ Caplet Phytopure Prenatal Vi-min Vitaday Tab Vitranol Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Pregnancy Multivitamin Folic 5 Iron Folate Plus Multi Spectrum - Tablet Multi Vitamin Drops with Fluoride with Iron CitraNatal Rx Puralor Super B Compound W 500mg Vit C Mangadyn OB Complete Prenatal Stress B Complex With C,e, Zinc and Copper Virt-Caps Prena1 PR Natal 400 Chewable Multiple Vitamins Plus Iron Tab Lysamine Diet Supp Amp-tab Virt-Tabs Vitaflex Dietary Suplement One A Day Multiple Vit W Minerals Livron Plus Ampoule Vitamines Et Mineraux Enfants 970 O-Cal Prenatal Vitamin Thrivite 19 Diaplex Vitafol One Neonatal Vitamin Extra P.N. Vitamin-mineral Drink Mix Croq-vit Pour Enfants Foltabs Prenatal Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass Lipo-B-C Tab Body Rox Dialyvite Supreme D Triveen-Duo DHA VitaXyme Folica-V Multivitamins and Multiminerals Formula Regular Tablet New Chapter's D'adamo 4 Your Type Multiple for Type O Swiss One Multivitamin and Mineral Caplet Children's Chew Multi & Min Tab Myhephron Dialysis and Stress Supplement Keylosa Vitamines Pour Bebes Et Enfants Chewable Multivitamins Tandem Plus Multivitamin & Minerals (iron Free) Cedevita Plus Vitamin Supplement Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Livita Children Stress Formula B-comp + 500mg Vit C Tab M.V.I. Pediatric Pregvit Twin G.F. Powder Vanilla Flavor WestGel DHA Multi Tabs Super Kids Chewable Multivitamin Multimineral (chewable Tablets) Beminal W C Fortis Inj Super Charged Energy B Complex 25mg Vitamin Supplement Cavan Prenatal Liqui B Complex Supplement De Multivitamines Infusion Arome Fruits Rouges Thiamine Hydrochloride Injection USP, 100mg/ml Poly-Vitamin with Fluoride Viva Kids - Tab NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vital Be-100 Hi Potency Multi Tab Multivitamins W Iron Swiss One Multi Vit & Chel Min Tab Derma-force Multiple Vit Plus Iron Tab Pnv Ob DHA Floradix Formula Liq Dexatran Bev B-150 Infantol Drops Prenatal Swiss Total One Poly-VI-flor VP-Vite Rx Duet DHA 400 Super Multi Advanced B & T Formula Totalvit Plus Spectrum Performa Multivitamins and Minerals Tablets Obstetrix DHA Combo Pack Chela-chromium 200 Dialyvite with Zinc Multiple Vitamins and Minerals Capsules Pretrate Vitamin B1 100mg For Kids Only Chewable Multivit. Plus Iron Premium Prenatal Livron Plus Tab K.L. Vitamin-mineral Only One - Tablet Children's Chewable Multivitamin and Multimineral Allbee With C 550 Cap B1 400mg Ctr Tab Beminal 500 Tab Vena-Bal DHA Hylazinc Total Living Concepts Formula One - Tab Folika-T Virt-PN B Complex With C 550mg Dia-vite Twin Ultra Liquid Fruit Punch Flavor B Complex 500 Tab Lexazin Children's Chewable Multi-vitamin Complete With Minerals Hemarexin Amp PNV-Select Medi Msm (methyl Sulfonyl Methane) Zalvit MultiVitamin with Fluoride Chewable Complexe B-75 Chewable Children's Complete Multivitamins With Essential Minerals B-50 Complex Vitamin B Compound With Vitamin C Fortis Capsule Dtc Paramettes Chewable Multivitamins Plus Iron Cavan Folate OB Vitrexate B Complex Plus C 300mg Tab Children's Chewable With Iron Stress Formula + Iron Gtf Support Caplet Se-Natal One Vita Plex Tab Swical-energy 3e Age Senior Multi One Vit-HA Multi Vitamin and Zinc Supplement Chela Iron Plus C,b Complex Children's Chewable Multi-vitamin Multi-Vitamin with Fluoride Balanced B 125 Srt Kanga-B Vitamin B Group + C Multra Plex Nutri-Tab OB plus DHA Swical-energy-2 Liqui Vita Paramettes Chewable Multivits With Iron Tab Twin Ultra Liquid Orange Flavor Multivitamin & Multimineral Multiple Vitamins Childrens Chewable Vitachrom Gc Complete Mega B Paramettes Syrup Bewon Elixir 0.05mg/ml Formula Lf C-Nate DHA For Kids Only Chewable Multivitamins - Tab Forty Plus Vitamin Supplement Innersource Tab Multi Vitamin, Iron and Fluoride Stress B With 1000 Mg Vitamin C Strovite Forte Caplet Childrens Chewable Vitamins NovaFerrum Multivitamin with Iron Pediatric Drops Children's Chewable Multiple Vit.plus Iron Twin Opti Pwr Vitramyn Vitamin B Complex Tab B Plus C 300 mg CitraNatal Assure Foltabs Prenatal Plus DHA Stress Vitamin B With C Complex Tablets Kanga-V Multivitamins & Minerals Ferra Naka Plus Vitamins Multivitamins and Minerals for Men Prenatvite Stress B Complex With C, E & Iron B Complex W Vitamin C Fortis Cap Infuvite Pediatric Stress Tab With Zinc, Copper and Vitamin E Vita-B-75 Cap Thiamine Hydrochloride Injection, USP Nutra Boost Women's Biomultiple Vitamin and Mineral Supplement Prenatrix Vitamin B-Complex RayaVit B-Combo FolaMed DHA Nutra-clear Balanced B-100 Timed Release Multi Enfants Tab Multivitamin Prenatal Vitamin and Mineral Supplement -tab Taron-C DHA Tricare Prenatal Compleat Trinaz Animal Shapes Multivitamin with 0.25 mg Fluoride Zoo Chews Plus Iron Vitamine B1 Tab 100mg USP Dexatrim Tablets vitaMedMD One Rx B-plex 100 Multiple Vitamins W Iron Tab B-complex With Vitamin C, Biotin, Folic Acid Chewable Multiple Vitamins Tab Vit B Complex Plus Vit C 550mg Mega Plex IV - Pck B Vitamin Compound With B12 Thunas Cda-21 Vitamins With Non-medicinal Probiotic Complex Fizz Multivitamins for Kids W C Loz Folivane-OB Liqui B Complex Plus Thiamine Hydrochloride Garfield Chewable Multivits Plus Iron Tab Timed Release B-complex 100 Vitamin B Compound W Vit C 250mg Tab Virt-Nate DHA Thiamine HCl 100mg W C 20mg Multi Vitamin Plus Iron Paire OB Plus DHA Se-Natal Children's Multivitamins Virt Vite GT Active FE Hemarexin Liquid and Drinkable Ampoules Lipotropic Ctr Multivitamin with 1.0 mg Fluoride Vasculine Mvc 9+4 Inj Multi-12/k1 Pediatric Venexa FE Vitrexate FE Maxi 10 Tab L.C. Supplement B C Antistress Cap RenaPlex P.N. Vitamin-mineral Drink OB Complete Petite Alkadrenergy Tablets Vitamin B Complex Stress Complex 600 Avec Vit E Cuivre Zinc Tricare Prenatal B-plus - Tab Vitamin B Complex Suppl Complete-RF Prenatal Hi Potency Stress B Tension With C Thiamine HCl Tab 50mg Childrens Chewable Multivitamins W Iron Folet DHA Neo-vites & Minerals Tab Am Caps Se-Natal 19 Chewable Childrens Chewable Multiple Vitamins Formula B Vp-pnv-dha Bev 29 Tab Nutrol-B-complex Mor-vites Tab Manganese 50mg Plus B1 & E Tab Multi-actin Multi Vitamin with Fluoride B-50 Complex Tab Choice OB DHA Onccor Sopalamine/3b Tab Multipack II P.N.P. Vitamin Drink Formula Fm Vitamins & Minerals Tab Multisol Pediatric Infuvite Multiple Vitamins 24 Multivitamins + Minerals Centratex Natal-V RX Multi-vitamin/Multi-mineral Bal-Care DHA Essential Mega 13 Multivitamin Formula Hi Potency B52 B Complex Tab Orifer F Adult Formula 50+ Leritone Junior Pnv-OB-dha Vitaphil 90 DHA WesTab Plus Vitamin B Compound Tab Fortistress Tab Davimet-M Paramettes Multivits Plus Iron Tab (teens) B Totum 500 Ultimate OB DHA Multiple Vitamins Tab Neo Bex Elixir Complex-75 Thiamine HCl Tab 25mg Tender Age Multi Vitamins Prenatryl B50 B Complex Tab Hypo Vites Tab Super Vita-vim With Beta-carotene - Tab Cyroplex Formula Gly Genicin Vita-Q Somavit Brand Vitamins and Minerals Complex Allbee C 800 Tab Vitamin B Cpd W Vit C Tab Vitamin B Complex 100 Tab Potassium Plus Vit B Complex Thiamiject Injection - Liq Im IV 100mg/ml Men's Biomultiple Vitamin and Mineral Supplement Multivitamines Pour Enfants (chewable Tablets) Children Choice Multivit Chewable Tab Complexe B Compose 75 Daily Energy Brand B-complex Pro Hers Vanilla Multinate DHA Surbex-500 With Iron Mega-vim 75 With Beta-carotene - Tablets Stress B-complex Plus Iron With Vitamins C&e Vtb Vitamin and Mineral Supplement Lorid Escavite D Dialyvite 3000 Dermamed Nutrition for troubled skin Multi-Vitamin Drops with Fluoride and Iron Prenatal Vitamins Plus Super Vitalex Ampoule Buvable Vitamin & Mineral Formula 1 Dietary Supplement Formula Pro-B Prenatal Formula Tab Twin Ultra Liquid Lemon-lime Flavor Chromease Tab Master Key Multi Vitamin Multi Mineral Formula 2 One-A-day Advance Men's B1 Tab 100mg Vp-heme Ob DHA One A Day Advance Adults 50+ Vyqua Vinate AZ Women's Formula Super Stress Capsules Meplex T 750 Materna - Tab OB Complete DHA Vitamin B + C Cap Vitamin B1 Tablets 100mg Vitamin B Complex 50 Reno Caps FolaGent DHA Super Vita Vim Multivitamins and Minerals Super Pantoplex Children's Vitamins W Iron Chewable Distilpure Msm Poly-Vi-Flor Children's Chewable Multivitamins With Minerals RE Prenatal Multivitamin with Iron Cal M Tab Poly-Vite/Iron Oral Solution Floravit - Syr Provida OB Multivitamins and Minerals Tablets PNV Prenatal Vitamin Plus Vitamin A Adult Infuvite Multiple Vitamins Multi #2 Re Ob 90 DHA Thiamine HCl Inj 100mg/ml Mycelized Childrens Multi-vitamin Liq Nutri-Tab OB Venexa Usana Megavitamin Tablets - Tab Milltrium Senior Vitamin and Mineral Supplement Daily Balance Tab Poly-Vite Pediatric Oral Solution B Complex With C 300mg Tab Multiple Vitamin Plus Minerals Tab Gesticare DHA Kid's Choice Children's Chewable Vitamins - Tab Formula O.C. Nutra-Z Floriva Plus PR Natal 430 Premium Prenatal - Tablets Stress Formula Multi-B Comp + 500mg Vit C Cap B6 Plus Tab Numark Multivitamins Trinatal Rx 1 Super Stress Mega B Plus 1000mg Vit C Tab Childrens Chewable Multiple Vitamins Plus Fe B Complex W C and B12 Inj One Daily VITES SetonET-EC Dayavite Natalvirt 90dha Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Vitamine B1 100 Mg - Tablet Zoo Chews Materna Ellis Tonic Megavite Rx Vege Swiss One Multivitamin W Chel Mins Tab Adeks Tablets Folic-K Lipovite High Potency Multivitamins & Minerals Caplets MVC-Fluoride Nata Komplete Tonicol Et A-D-C Ampoules/comprimes CitraNatal 90 DHA Ziphex Stress Tab With Iron and Vitamin E Stress Formula Vit B With C Complex Envirocomplex Stress Forte Plus Lipotropic Factors MultiVitamin with Fluoride Cavan Alpha Natural Source Spectrum With Beta Carotene Quflora FE Vitamin B Compound W C Tab 500mg Multi Flow Tablets Chewable Multiple Vit Plus Iron for Children Vitaday Junior Tab Children's Chewable Multivitamins and Minerals Multivit Et Fer Ampoules Et Comprimes Multi B One A Day Advance Fem Multi 1000 Maxum Multi-vite Dynam Ampoule Et Tablet B-50 Hi Potency B Vitamins Tab Avon Vitadvance Multi-kids Complete B50 Complex Prenatabs FA Tini-cal Ampoules Viva CT Prenatal Virt Nate B Stress C + Iron & Vite TL-Folate Multiple Vitamin Tab NovaMV Multivitamin Duet DHA Multi Vitamin & Minerals Permathene-12 - Caplet Feminique W Iron and Calcium Tab Childrens Chewable Vitamins W Iron Bacmin 50 Plus Multiple Vitamins & Minerals Maxi 6 Liq Cavan Folate DHA Vitamin B Complex W C 300mg Tab Gestamine Comprimes Animal Shapes w/Iron Chewtabs Vitrexyl Chewable Adult Multivitamins With Minerals Vitalife - Capsule Phosthenine Vitamines Et Fer (ampoules Buvable) Prenatal and Post Partum Supplement Mvc Beminal Fortis Elx Card-floe II Tab Dexifol Multivitamins W Minerals Extra Strength Integra Plus Neonatal DHA Thiamine HCl Injection - Liq 100mg/ml Complete Multivitamins and Minerals for Children Vitafol Caplet One Tablet Daily Mens Formula Stress Tab Stresstabs + Zinc-copper Vitamin B-1 Thiamine HCl 100mg Childrens Chewable Vitamin Tab M.V.I.-12 Vitazyme L.G.I.T. TriAdvance B-complex Tablets B Complex 50 Vitamin Cap Vital-D Rx Vitamin B Complex W C Tab Vitamin B1 Tab 100mg USP Neonatal Plus Vitamin Hi Potency Balanced B-100 Complex - Tab Complete Natal DHA Vitamines Et Mineraux Vitamines Et Mineraux Comprimes Poly-Vi-Flor with Iron B-complex Tab Children's Chewable Multiple Vitamins - Tab HemeNatal OB Thiamine HCl Tab 100mg Natavite Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Cc II Childrens Chewable Tab PNV-First Ultimate Tab Vitamin B-1 100 Mg Tablets Replavite NESTABS Prenatal Multi-vitamin/Mineral Supplement Grand Master Formula Tab Natal PNV PureFe Plus Trinatal Ultra Multivitamine RE Nata Concept OB Gemvites Jr Tab Chewable Virt-Nate B-complex Swiss One PROTECT IRON Liquid C. Vit-min Formula Biovita Preplus Amladex Maltlevol 12 Liq B-complex 100 Vitranol Fe Enviroflex - Tab Multitam Natalvirt Ca Moms Choice Rx Childrens Chewable Multivitamins Twin G.F. Powder Davimet Multivitamins for Children SetonET Original Bioscal Forte Multi-vitamin Supplement Capsules Timed Release Vita-vim Srt Harvest Of Values All B Complex Tab Trinatal GT Balanced B-50 B-complex Vitamins, Timed Rele Century Complete Extra Once A Day Multra With Iron Foliflex Fem Time Tab Multi-Vit-Flor P.R.O. Complex Children's Vitamins Chewable Children's Chewable Multi Vit W Iron Geritol Liquid Toni Com Liq Vitamin B Complex 100 Vp-heme Ob Somarexin and C 1000 DuetDHA Complete Vitamine 110 Liq Select OB Vol-Nate Dialyvite Kanga-kid Vitamins & Iron Multi Vitamins & Minerals Multicaps Great Day/am Formula Tab Multitabs B-complex 50 Garfield Chewable Multivitamins Tab Acti-MN + B1 + C Caplet Neomultivite Azesco Paramettes Adults TL-Care DHA Stress Formula Tab Irospan 24/6 Duet DHA 400 ec Hylavite Prenatal, DHA Vitasure Essential Vitamins and Minerals Gynedyn Tab Neonatal19 Revit Multi-vitamins and Minerals Tricare Prenatal DHA One Rx Multivitamin PNV Prenatal Plus Multivitamin Virt-Bal DHA Plus Magnum-75 Vitamin and Mineral Supplement Multiple Vitamins With Minerals Tablets MultiVitamin Drops with Fluoride and Iron CompleteNate Chewable Fortamines-10 Comprimes M.V.I. Paediatric Multi Vite Liq Junior Kids Stuff Tablets Supravite Stress Avec Vit E B Complex Tablets Pro His Mint Multi-force for Women Tab Efferlife Multivitamins and Minerals Sopalamine/3b Plus C Spark Cap Complete One A Day Tab Sopalamine 3b Plus Multivitamin with Fluoride Phytoplex B Liq Folitin-Z Multi Vitamines - Liq TriphroCaps Vitafol OB Caplet M-Natal Plus Pregvit Folic 4 For-2 Central-vite 18 Essential Virt-Pn WesCap-C-DHA Multiple Vitamins & Minerals Tablets Zintrexyl-C Prenatol-M Multiple Vitamins With Iron Tablets Multivitamins and Minerals for Young Men Se-Plete DHA Se-Care Conceive Childrens Chewable Multiple Vitamins Tab Childrens Multiple Vit and Min Chew Tab Rocky Mountain Multiple Vit and Min Mega Tab Multivit with Fluoride Multi-Vitamin Fluoride tensioSAN Multivitamins Prenatal Plus Focalgin 90 DHA Men's B Complex W C Forte Cap RE Nata OB Davimet with Fluoride Kaydia Patch Revitalize Multi-vitamin and Mineral Complex Vitafol Plus Prim - Royal P.M.T. Multi Vitamin and Mineral vitamin Stress Formula Multivitamin Tablets USP One-A-day Advance Fem - Tablets Thiamine Prenara Balanced B100 AzesChew Multi 12 Injection TL-Fluorivite Everyday Multiple Vitamins Focalgin CA OB Complete 400 Abavite Prenatal Plus Multivitamin Plus DHA MiniCaps Stress B Complex With C, E and Iron Tab B Virol Essential B Tablets Multi Plex II - Tab Reaphirm Plant Source DHA Vitrexyl plus Iron Children's Chewable Multi Vitamins Multi-12 Pediatric Multi-Vitamin Fluoride and Iron Drops MultiVitamin, Iron and Fluoride Drops Multi Rol Daily-Vite V-Natal Super Daily No 2 Orange Flavored Crystal Chews Tab Complete One-A-day - Tab healthy mamaBE WELL ROUNDED BE WELL ROUNDED Children's Chewable Multivitamin Complete With Minerals D'pantothenic Acid-B1-B2 Tab Flintstones W Extra C Tab Multi-force for Adults Tab Strovite One Caplets Edge OB Balanced B-50 B-complex Vitamins Tab Multi-vitamins Multivitamines Et Mineraux Junior Regulier Gtf-vitamin-minerals & Pancreatin Tab Adeks - Dps Chewable Multivitamins Plus Iron Liqui Infant Vitamins NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Supravite Stress Avec Vit E Et Fer MultiVitamin with Fluoride Drops PR Natal 430 ec Chela Potassium Plus Polymine Avec Zinc Et Cuivre Multi Vitamin Drops with Fluoride and Iron Revival 1 Tab Stress B Complex With C and E Tab Vitamin B1 Tab 100mg Vita Vim With Beta Carotene-caplet Escavite Lq Multiple Vitamins W Minerals Tab Dothelle DHA Cavan Heme OB Hill.vite Hi Potency B Complex W Chelated Minerals 50 Plus Multi-kid Phytovim Cap Pregnancy Multivitamin PreNatal Vitamins Plus Multivitamines Plus Fer Pour Enfants (chewable Tablets) Vasodyn Tab M.V.I. Adult Complete Multivitamins and Minerals Tablets Timed Release Stress B&c Tab Zatean-Pn Multiple Vitamins and Minerals For Kids Only Chewable Multivitamins Mini-B Tab Dialyvite 5000 Megavites Tab Stress Formula Biovim Tab Stress Tablets Formula D.S. Tricare Prenatal DHA One With Folate One Per Day Vitamin and Mineral Dietary Supplement Omniquin One A Day Advance Adults Stress Ctr Srt Vitogen B Stress C600 Multi-11 Niva-Plus Formula Gm Everyday Multiple Vitamins With Iron Vit B Complex Ctr Palm Springs Multvit and Min Tab Children Choice Multivitamin W Iron Chew Tab Vita Day Tab Vyo Cylate - Pwr Multi Nt-OX Nephron FA NataChew B Compound 50mg Tab Sun-rype Vitaburst Fortaplex Inj PureVit DualFe Plus Active OB Surbex-500 With Zinc PR Natal 400 ec Prevital Tab Folika-V Vitamin B1 Appedrine Hemarexin Tab L-Methyl PNV DHA Multi-phyto Capsules Glyco Plus Ect Vitamin B1 Tab 2mg USP Tricare Prenatal 2-part Daily Prenatal Vitamin System B-plex Quflora FE Pediatric Drops Nitro Vites - Tab Bugs Bunny Chew Multi Vit Plus Iron Vol-Plus Ultra Enerforce B-1 Caps 500mg Prenatal Vitamins Plus Low Iron Vita-B Flintstones Multiple Vitamins Prenatal Vitamins and Minerals Tablets H.W. Children's Chewable Multi Vit & Mineral Neo-bex Injectable WesNate DHA Neo Vites Tab Multivit-liq NEONATAL Complete C.R.T. X Multivitamin & Mineral Powder Mix O-Cal FA multivitamin PreQue 10 Vita-vim With Beta-carotene - Tab PureFe OB Plus Vit B1 Ctr Srt 100mg C-force Multi-vitamins With Minerals Multivitamines Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Glyco-aide Tab Betaxin Multi-Nate 30 Betaxin Liq 100mg/ml Jenliva Vitamin B Complex Plus C 300mg Timed Release Olympian Multi Vit Plus Minerals Tab Novel Vita B Complex With C 300mg Virt-Advance Swiss One Timed Release Tab M.V.I. 12 Men's 50+ Multi II IV Vi Tab Surbex 500 Filmtab High Potency Vitamin B Complex + C Tab Vitamin B Tablets Zeldana Prenatal Mega Antioxidant Nephrocaps Zyvit Children's Chewable Multiple Vitamins (chewable Tablets) Multivitamin Drops with Fluoride VIL-Rx Vita B + C 500 Tab Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Prenatal Vitamin and Mineral Supplement Maintain Multiple Vitamin & Minerals Vitafer - Liq Wellness Formula Maximum Once A Day Chewable Multiple Vitamins Plus Extra C Corvite Free Glyco Lite Ect Xyzbac G V & M Vitamin and Mineral Supplement T.R.I. B-plex Src Penta-thion Pwr Prenatal Vitamin and Mineral Supplement Tab RenaPlex-D WesCaps Chewable Multiple Vitamins for Children Kenwood Liquid Supplement Ply Vi Sol Chewable Tab Ventrixyl Stressmates Multivitamins and Minerals for Young Women Q.T. #4 Vitamin and Mineral Dietary Supplement Renate DHA vitaMedMD Rx Plus Vita Balance 2000 Multi Vitamin and Fluoride Formula F L W Vitamin B Complex Plus 300mg Vitamin C Classic Swiss One 10 Multivitamin and Mineral Tab Methaver Prenate Elite Vitamin and Mineral Supplement - Liq Duet DHA Balanced Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Vege 1 Daily Tab Enrich Core Pack - Children Vitamin and Mineral Supplement TRONVite INATAL Ultra PrePLUS Poly Vi Flor Chewable Tab Oncovite Prenatal Supplement - Tab HemeNatal OB plus DHA Poly-Vi-Sol Beminal With C Fortis Cap Balanced B50 Complex Mega Capsules Mvc 9 Plus 3 Inj PNV Ferrous Fumarate Docusate Folic Acid FloraFol Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Hyporyl - Tab Multitol-M C-B Complex B Plus C 300mg Timed Release Right Choice A.M. Multi Formula - Caplet Super-pote Vitamin Supplement Escavite Prenatal Plus Vitamins Nutrilite Double X THIAMINE HCl Protect Plus SO 60 Time Release B 100 Compound - Tablet Omnivex Supravite Bouteille 250ml Omega-3 Rx Complete Doctor's Choice Brand for Men TriStart DHA Children's Multivitamins With Iron Beminal With C Fortis Pws VitaPhil Aide Multi-vitamines Enfants Comprime Xyzbac Revitex Ampoules Et Comprimes G.A.S. Complex Multi-Vit with Fluoride and Iron Zavitrol Prenatal Plus Iron Vitaplex Chela-manganese 50 Plus Mega Balance Bewon Elixir PM Caps Vigem 12 Liquid Revit Tab Materna-tab Kanga-kid Multi-vitamin & Mineral Nrg Plus Liq One A Day Tab Vitafant Kids Stuff With Iron Tablets Flinstones Multiple Plus Iron THIAMINE HYDROCHLORIDE injection, solution Vita-amine Cap 100mg Folivane-Plus with Ascorbic Acid Precursors Multi-vitamin Dietary Supplement Iron, Vit & Min Supp Marnatal F Tandem OB Soluvit N Tonimol Cap Liq Renal Caps Dialysis/Stress Vitamin Supplement Synergistic Manganese Capsules Kanga Sport Vitamins B & C Plus Minerals Prenatvite Complete Prenatvite Plus Osteo-force CitraNatal Essence Mebolic Childrens Chewab Vitamin W Chel Minerals PreferaOB Acti-thiamine Caplet 100mg Prometa Supravite C 1000 Maxine Vitamin and Mineral Supplement Quflora Pediatric Drops Z Bec Tab Cavan-EC SOD DHA Children's Chewable Multi Vitamins With Iron Tablets Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Stress B & C Caplet OBTREX DHA Combo Pack PreGen DHA Alertonic Supravite Stress Avec Vit E Cuivre Et Zinc Fibrik MI-Vite RX Obstetrix EC Vitamin B Complex + C 600mg Tab Complexe B 75mg Sibergin B - Cap Bal-Care DHA Childrens Chew Multi Vitamin Tab Finazol Infant Multivitamin Drops B-100 Vitamin Supplement Multivitamins and Minerals With Betacarotene Tablets Floriva Low Potency B Complex Tab Multivitamins and Minerals - Complete Folika-NC Pnv-VP-U Xvite Supravite Pour Enfants Se-Natal 19 Vitamine Du Groupe B Plus Fer - Liq Children's Chewable Tab Dalivit Junior Multi Vitamins - Regular MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Luna Vitamin and Mineral Bar for Women Phytofortis + Calcium A-D bioJET Select-OB Plus DHA Prenatal Supplement Plus DHA Tendera-OB Mega Vitaminerals Opti-manganese + B1 + C Caplet Thiamine HCL 100 mg Complex 5 - Pwr NeuroBion Chew.multiple Vits.with Extra C for Children Balanced B-50 Complex Orti B PNV Tabs 29-1 Prena1 Plus Prefera OB plus DHA Q.T. Vitamin and Mineral Drink Mix Synergistic Manganese Cap Vitafol Fe Plus NephPlex Rx Multi-Vitamin Fluoride Drops Stress B Capsules With Vitamin C Multi Vitamin Drops with Fluoride B-100 Complex Tablets Multiple Vitamins Plus Iron Tab Se-Tan PLUS Virt-C DHA Vol-Care Rx Prenate Star Cedevita Sugar-free Vitamin Supplement Vita-worth B-complex Tablets Balanced B-complex Vit + Vit C&e Tab Flintstones Multiple Vitamins Tab Tricare Prenatal Quick Dissolve Multinate DHA Extra Multiple Vitamins Plus Iron for Women Vita-vim - Tab Vitamin B Complex + C 300mg Cap B-100 Caps CitraNatal DHA Thiamine Hydrochloride Inj 100mg/ml USP Fusion Plus Supravite 10ml Ampoule Vimeral Tab Mega Plex III - Pck Multi Vite Liq Adult Multiple Vitamins With Iron Vigo Multivitamins Drops/lozenge Vita-Pac WesNatal DHA Complete Antlerviron Vita-Rx Diabetic Vitamin Vitabanks Vitamin Tab PreNatal 19 Folica BE Viamon Ampoules Et Comprimes Thrivite Rx E.S.T. Complex Infuvite Adult Multi-Vitamin Multivitamins and Minerals for Women N.E.U. Complex Flintstones Multiple Vitamins Plus Iron Hormodausse Plus Calc Et D Tab Inatal Advance B-complex-50 Tab Maltlevol Liq Ultra Hr Vita Vim Multivitamins and Minerals Tab Carbassist Tablets Renate Childrens Chewable Multiple Vitamins W.iron Neo-bex Multiple Vitamins and Minerals Tab Revit Plus Cap Liquid B Complex 50 Multi-Vit with Fluoride Davimet with Iron DuetDHA Balanced Multi-Vitamin With Fluoride Kindervites Livita Adults Iron Polysaccharides Folic Acid DHA hormaSAN forte Pregvit Folic 5 Vc II Allbee With Vitamin C Cap Fortamines 10 Capsules Multi Vitamin - Mineral Multi Vitamin-mineral Formula Dexivite Formula Hh B 50 Capsules Poly-VI-sol Drops Infa Drops Multivitamins Virt-Vite Plus Vasula Tab PNV Prenatal Vitamin Spectrum 2 Cap Concept DHA Provida DHA Ventrixyl Fe Vitogen B Stress C Vit E Zinc & Cop RE FAC-x B-100 Hi Potency B Vitamins Tab PreTAB Kimchi Vitamin chewable multivitamin Elite OB Prenatal Multivitamin Multivitamin with fluoride Vitafol Ultra Corvite TM-Vite RX B With C 500 Cap Vitaphil DHA Vol-Tab Rx Timed Release B Complex 100 Srt Multivitamines Et Mineraux ahoSAN NataFort Children's Chewable Vit and Min Tab Multiple Vitamins Timed Release B-complex 50 Twin Ultra Liquid Grape Flavor Multiple Vitamins Plus Iron - Tab Multi Pro Multi Plex I - Tab Relnate DHA Isotonix Multitech Vitamin Mineral Supplemen PreferaOB plus DHA Genicin Vita-S Quflora Pediatric Multi - N.T.O.x Formula - Tab Balanced B-100 B-complex Vitamins Tab Bugs Bunny and Friends Multiple Vitamins Deriton Hemocyte Plus Nephrocaps-QT DaVITE Multiple Vitamins - Tablet Vita B Complex Tab Vitamin B1 100mg Tablet Thiamine Hydrochloride Inj 100mg/ml Men's Multi Master Formula
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682