VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB00152 ?
Name	Thiamine
Groups	approved vet_approved investigational nutraceutical
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	thiaminium Thiamine chloride Tiamina thiamine(1+) ion Thiamine Aneurin Thiamine mononitrate Antiberiberi factor Thiaminum Thiamine hydrochloride Thiamin Vitamin B1 thiamine(1+)
Brand Names	B-complex-50 Tab M-Natal Plus Poly Vi Flor Chewable Tab Se-Natal 19 Vitamin B1 100mg Tablet Nephrocaps Hemarexin Amp Children's Chew Multi & Min Tab Formula Gm Childrens Chewable Vitamins W Iron Medi Msm (methyl Sulfonyl Methane) Multiple Vitamins and Minerals Maltlevol Liq Multivitamin with 1.0 mg Fluoride vitaMedMD One Rx Twin Ultra Liquid Lemon-lime Flavor Super Pantoplex Nutri-Tab OB Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass Keylosa Ferra Naka Plus Vitamins Super Vitalex Ampoule Buvable Se-Tan PLUS Poly-Vite Pediatric Oral Solution Prenatal PR Natal 430 Multi-Vit with Fluoride Right Choice A.M. Multi Formula - Caplet INATAL Ultra Ultra Enerforce B Plus C 300 mg Neonatal DHA Multi Tabs Chela-chromium 200 WesNatal DHA Complete Multra With Iron MultiVitamin with Fluoride Drops Betaxin Liq 100mg/ml B Complex 500 Tab Multra Plex TRONVite Vita-B-75 Cap Multiple Vitamins W Minerals Tab RE FAC-x Stress B Capsules With Vitamin C Multitabs PrePLUS Mor-vites Tab B-complex 100 P.R.O. Complex Timed Release B-complex 100 Choice OB DHA Folica-V One Daily Vitamin and Mineral Dietary Supplement Quflora FE Pediatric Drops Pnv Ob DHA Hill.vite Vinate AZ Folivane-OB Balanced B-100 B-complex Vitamins Tab Revit Plus Cap Glyco Lite Ect RenaPlex-D Stress B Complex With C and E Tab Multi Vite Liq Adult Prenatal Supplement - Tab B-50 Hi Potency B Vitamins Tab Chela Iron Plus C,b Complex Men's NESTABS Prenatal Multi-vitamin/Mineral Supplement Stress Formula Tandem Plus One A Day Advance Fem RE Prenatal Multivitamin with Iron Vitamin B Complex Plus C 300mg Timed Release Centratex Natavite Poly-VI-sol Drops Complete Mega B Paire OB Plus DHA Balanced B-100 Timed Release Children's Chewable Multivitamins and Minerals Multi-Vitamin Fluoride and Iron Drops Phytoplex B Liq Poly-Vitamin with Fluoride Vita-Pac Vita-Rx Diabetic Vitamin Maltlevol 12 Liq Permathene-12 - Caplet Beminal With C Fortis Cap Vit B Complex Plus Vit C 550mg Time Release B 100 Compound - Tablet hormaSAN forte Multivitamin & Multimineral Tricare Prenatal DHA One Dexifol B6 Plus Tab Prenatvite Complete Vitamin B1 Tablets 100mg Twin Ultra Liquid Fruit Punch Flavor Stress Tab MultiVitamin with Fluoride Quflora FE Genicin Vita-S Cedevita Plus Vitamin Supplement Virt-Pn Puralor Thiamine Hydrochloride Inj 100mg/ml USP Vita-B M.V.I.-12 Diaplex Infant Multivitamin Drops Vol-Care Rx Multiple Vitamins Mega Vitaminerals Prenatal Vitamin and Mineral Supplement Tab Lipotropic Ctr Folika-T Myhephron Dialysis and Stress Supplement Xyzbac G Active FE Megavites Tab Multi Vitamin, Iron and Fluoride Thiamine Hydrochloride Injection USP, 100mg/ml Osteo-force Prenatryl Tonicol Et A-D-C Ampoules/comprimes Vita B + C 500 Tab Duet DHA 400 healthy mamaBE WELL ROUNDED BE WELL ROUNDED Men's 50+ 50 Plus Marnatal F Flintstones Multiple Vitamins Tab Multi #2 Dialyvite with Zinc Prenatal Plus Iron PNV Prenatal Vitamin Plus Vitamin A Lipovite Kanga-kid Multi-vitamin & Mineral D'pantothenic Acid-B1-B2 Tab Lorid Bewon Elixir 0.05mg/ml Formula Hh Thrivite Rx FloraFol Vitafol Fe Plus Vitamin B + C Cap Chela Potassium Plus Balanced B-50 B-complex Vitamins Tab Children's Chewable Multiple Vitamins - Tab Beminal W C Fortis Inj Body Rox Pregvit Folic 4 Vita-vim - Tab Twin G.F. Powder Croq-vit Pour Enfants Stress Complex 600 Avec Vit E Cuivre Zinc Vitasure Women's Biomultiple Vitamin and Mineral Supplement Multi Enfants Tab Super Daily No 2 PreNatal Vitamins Plus Prenatal Plus Vitamins Jenliva Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Replavite Zyvit B Stress C + Iron & Vite Liqui Infant Vitamins Vital-D Rx Fusion Plus Pro Hers Vanilla PR Natal 400 ec vitaMedMD Rx Plus Stress Formula Multi-B Comp + 500mg Vit C Cap M.V.I. 12 Century Complete B Totum 500 Complete-RF Prenatal Twin Ultra Liquid Grape Flavor Supplement De Multivitamines Infusion Arome Fruits Rouges Timed Release B-complex 50 NEONATAL Complete Novel Vita Mega 13 Multivitamin Formula Kids Stuff With Iron Tablets Vasculine Cavan Folate OB Vitamin B Compound W Vit C 250mg Tab Neo Bex Elixir Vita Vim Multivitamins and Minerals Tab Vita Balance 2000 Multivitamins and Minerals for Young Women Vtb Vitamin and Mineral Supplement Multinate DHA Extra Multicaps Neo-bex Neonatal Plus Vitamin Feminique W Iron and Calcium Tab Vege Swiss One Multivitamin W Chel Mins Tab Balanced B-complex Vit + Vit C&e Tab Vitrexyl plus Iron Acti-MN + B1 + C Caplet Adult Infuvite Multiple Vitamins Corvite Swical-energy 3e Age TriAdvance Vitafer - Liq Balanced B50 Complex Mini-B Tab One Tablet Daily Mens Formula DaVITE Ultimate OB DHA Swiss One Multivitamin and Mineral Caplet Childrens Chewable Vitamins Mangadyn Inatal Advance OBTREX DHA Combo Pack Hypo Vites Tab Children's Vitamins W Iron Chewable Multivitamins and Minerals - Complete Oncovite Multivitamin with fluoride Multivitamines Pour Enfants (chewable Tablets) Cavan Folate DHA Vita Vim With Beta Carotene-caplet Revit Tab Childrens Chewable Multiple Vitamins Tab Formula F L W L.C. Supplement Duet DHA Balanced Iron Folate Plus Multi 12 Injection One A Day Advance Adults 50+ Vitamin B-1 Thiamine HCl 100mg Vitamin B1 Multivitamins and Multiminerals Formula Regular Tablet Multiple Vitamins With Minerals Tablets Orange Flavored Crystal Chews Tab Prenatrix Quflora Pediatric Trinatal Ultra Stress B-complex Plus Iron With Vitamins C&e Hemarexin Tab Fortamines 10 Capsules Childrens Chewab Vitamin W Chel Minerals Childrens Chewable Multiple Vitamins Plus Fe Hi Potency Multi Tab Focalgin CA Appedrine Vimeral Tab Complex-75 AzesChew Azesco Thiamiject Injection - Liq Im IV 100mg/ml Distilpure Msm Dia-vite Virt-Caps Supravite Stress Avec Vit E Cuivre Et Zinc Nutra Boost Thiamine HCL 100 mg Multivitamins Vol-Nate Adeks - Dps Escavite Multi Nt-OX Renate Omega-3 Rx Complete K.L. Vitamin-mineral Timed Release B Complex 100 Srt Zintrexyl-C Biovim Tab Tender Age Multi Vitamins Stress Tab With Zinc, Copper and Vitamin E Vitamin B Complex Plus 300mg Vitamin C Zeldana Sopalamine 3b Plus Vitafol-OB Plus DHA Prenatal Supplement Plus DHA NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Multi-Nate 30 MVC-Fluoride Complexe B 75mg Davimet with Iron B With C 500 Cap Derma-force Prenatal, DHA Materna - Tab Stress B Complex With C, E & Iron One Per Day Vitamin and Mineral Dietary Supplement Card-floe II Tab Cavan-EC SOD DHA Supravite 10ml Ampoule Escavite D Iberet 500 NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Dynam Ampoule Et Tablet Dexivite Provida DHA Prenatal Vitamin and Mineral Supplement Vita-amine Cap 100mg Folic-K Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Thiamine Finazol Alertonic Complex 5 - Pwr DuetDHA Balanced Chewable Multivitamins Plus Iron Multi-11 One-A-day Advance Men's Orifer F PureFe Plus Chromease Tab Children's Chewable Multivitamin and Multimineral Supravite Stress Avec Vit E Vitafol Caplet Tricare Prenatal DHA One Rx Multivitamin Poly-Vi-Flor with Iron Phytofortis + Calcium A-D For-2 Liquid B Complex 50 Super Charged Energy Kid's Choice Children's Chewable Vitamins - Tab Tonimol Cap Liq Liqui B Complex Livron Plus Ampoule THIAMINE HCl Viva Kids - Tab Vitamin B Complex 50 Children's Chewable Multi-vitamin Premium Prenatal - Tablets Children's Chewable Multi Vit W Iron Meplex T 750 Avon Vitadvance Multi-kids Complete Multi Flow Tablets PreferaOB plus DHA Davimet with Fluoride Thiamine Hydrochloride Injection, USP For Kids Only Chewable Multivitamins - Tab Natalvirt 90dha Pregnancy Multivitamin Prenatal Mega Antioxidant Children's Chewable Multi-vitamin Complete With Minerals Vitamin B Complex Suppl Spectrum Performa Multivitamins and Minerals Tablets Manganese 50mg Plus B1 & E Tab Multi II IV Vi Tab Prenatal Vitamin and Mineral Supplement -tab H.W. Children's Chewable Multi Vit & Mineral Vitamin B Compound W C Tab 500mg Dexatran Multivitamines Et Mineraux B Plus C 300mg Timed Release Mega Balance Pediatric Infuvite Multiple Vitamins Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Childrens Chewable Multiple Vitamins W.iron Fem Time Tab B1 400mg Ctr Tab Insur-all Vitamin Supplement Vitamin B-Complex Cal M Tab Vitamin B1 Tab 100mg Chewable Multiple Vit Plus Iron for Children Nitro Vites - Tab Tricare Prenatal DHA One With Folate Allbee C 800 Tab Multiple Vit Plus Iron Tab Prena1 TL-Care DHA Childrens Chewable Multivitamins Multi Vitamin-mineral Formula Q.T. #4 Vitamin and Mineral Dietary Supplement CitraNatal Rx Vitamin B Compound With Vitamin C Fortis Capsule Dtc Gtf Support Caplet Vitamin & Mineral Formula 1 Dietary Supplement Sibergin B - Cap Pnv-VP-U Wellness Formula Zalvit Multi Pro Relnate DHA Multi-actin Fortaplex Inj SetonET-EC Opti-manganese + B1 + C Caplet Vita B Complex Tab Vitamin B1 Tab 100mg USP Vitamin B Complex 100 Tab Vasula Tab Multi-12/k1 Pediatric Maxum Multi-vite Nutra-clear Extra P.N. Vitamin-mineral Drink Mix Junior Multi Vitamins - Regular Glyco-aide Tab Complete Natal DHA Stress Tablets Vitamin B Complex + C 300mg Cap WestGel DHA Multi-force for Adults Tab Mvc 9 Plus 3 Inj Animal Shapes w/Iron Chewtabs Multitol-M NephPlex Rx M.V.I. Adult Multitam Vitramyn Reno Caps DuetDHA Complete Kimchi Vitamin chewable multivitamin Kenwood Liquid Supplement PNV Ferrous Fumarate Docusate Folic Acid Formula Pro-B V & M Vitamin and Mineral Supplement Vitamin B Complex 100 Women's Formula Re Ob 90 DHA Vitafol One Vit-HA Multi Vitamin and Zinc Supplement Livron Plus Tab Multi Vitamin with Fluoride Multiple Vitamins - Tablet Prenatal Plus Multivitamin Plus DHA MiniCaps Renate DHA Essential B Tablets Vege 1 Daily Tab Paramettes Chewable Multivitamins Plus Iron Lipo-B-C Tab Select-OB Plus DHA Prenatal Supplement Plus DHA Chew.multiple Vits.with Extra C for Children Lysamine Diet Supp Amp-tab Grand Master Formula Tab B Complex W Vitamin C Fortis Cap Somarexin and C 1000 Daily-Vite Infantol Drops Master Key Multi Vitamin Multi Mineral Formula 2 Mega Plex IV - Pck Vena-Bal DHA Abavite Se-Natal 19 Chewable Kids Stuff Tablets Vitamine B1 100 Mg - Tablet Nutrol-B-complex MI-Vite RX Stress Vitamin B With C Complex Tablets Vitamin B Complex Tab OB Complete DHA Childrens Chewable Tab Multiple Vitamins and Minerals Tab Tricare Prenatal Megavite Rx Cavan Prenatal Geritol Liquid Super Vita Vim Multivitamins and Minerals Vigem 12 Liquid Children's Chewable Multi Vitamins Multi 1000 PreferaOB Prenatal Plus Spark Cap TL-Folate Vigo Multivitamins Drops/lozenge Children's Chewable Multivitamins With Minerals Potassium Plus Vit B Complex Concept OB Virt-Vite Plus Preplus B Complex With C 550mg Vital Be-100 Vitogen B Stress C600 Carbassist Tablets Multiple Vitamin Tab PM Caps Thiamine Hydrochloride Inj 100mg/ml Beminal Fortis Elx Chela-manganese 50 Plus Obstetrix EC Prenatabs FA Prenatal and Post Partum Supplement Vitafol Ultra B-50 Complex Stress Formula B-comp + 500mg Vit C Tab Vitamines Et Mineraux Comprimes Garfield Chewable Multivitamins Tab Vitazyme 50 Plus Multiple Vitamins & Minerals Revitalize Multi-vitamin and Mineral Complex Bugs Bunny Chew Multi Vit Plus Iron Edge OB Vinacal Vitrexate Folitin-Z bioJET Multi Vitamin Drops with Fluoride and Iron CitraNatal Assure Dialyvite Supreme D Multi-vitamins With Minerals Antlerviron One A Day Tab Surbex 500 Filmtab Trinatal Rx 1 Pretrate Vitalife - Capsule Multiple Vitamins & Minerals Tablets Toni Com Liq Multi-phyto Capsules Advanced B & T Formula Multi Vitamin - Mineral Vitamin B Complex Vp-heme Ob DHA Super B Compound W 500mg Vit C Multi Vitamin Drops with Fluoride with Iron Multivitamines Paramettes Syrup Ply Vi Sol Chewable Tab Rocky Mountain Multiple Vit and Min Mega Tab Vitamin B-1 100 Mg Tablets One Daily VITES Hi Potency B52 B Complex Tab Cedevita Sugar-free Vitamin Supplement B Complex 50+ Caplet Swical-energy-2 Thiamine HCl Inj 100mg/ml Vitaflex Dietary Suplement PreNatal 19 Supravite Pour Enfants OB Complete Prenatal WesCaps Formula D.S. Glyco Plus Ect For Kids Only Chewable Multivitamins B-complex 50 Natalvirt Ca Stress Forte Plus Lipotropic Factors Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) C. Vit-min Formula Multivitamins W Minerals Extra Strength Vit B1 Ctr Srt 100mg PNV Tabs 29-1 Original Bioscal Forte Multi-vitamin Supplement Capsules Stresstabs + Zinc-copper Super-pote Vitamin Supplement B1 Tab 100mg Neomultivite Tandem OB Bugs Bunny and Friends Multiple Vitamins Chewable Multiple Vitamins Tab Magnum-75 Vitamin and Mineral Supplement Acti-thiamine Caplet 100mg Renal Caps Dialysis/Stress Vitamin Supplement Hi Potency B Complex W Chelated Minerals Amladex TL-Fluorivite Vitranol Doctor's Choice Brand for Men Bev B-150 B C Antistress Cap Olympian Multi Vit Plus Minerals Tab Kanga Sport Vitamins B & C Plus Minerals C.R.T. X Multivitamin & Mineral Powder Mix Liqui B Complex Plus Multivitamins and Minerals for Young Men P.N.P. Vitamin Drink PNV-First CitraNatal 90 DHA Children's Chewable Multiple Vit.plus Iron Iron Polysaccharides Folic Acid DHA Maxi 10 Tab Vita Plex Tab Supravite Bouteille 250ml Neo-bex Injectable Complete Multivitamins and Minerals for Children Children's Chewable Multi Vitamins With Iron Tablets Swiss One Timed Release Tab Twin Opti Pwr Ultimate Tab B-plex Protect Plus SO 60 B-complex Tablets Folica BE Flintstones Multiple Vitamins Infuvite Pediatric Bewon Elixir Multiple Vitamins With Iron NovaFerrum Multivitamin with Iron Pediatric Drops Prenate Elite Folika-NC Stressmates Flintstones Multiple Vitamins Plus Iron Super Stress Mega B Plus 1000mg Vit C Tab Chewable Multiple Vitamins for Children Poly-Vite/Iron Oral Solution CitraNatal Essence Virt-C DHA B Complex W C and B12 Inj Foltabs Prenatal Plus DHA Thiamine HCl Tab 100mg PureVit DualFe Plus Natural Source Spectrum With Beta Carotene O-Cal FA multivitamin Nutri-Tab OB plus DHA Livita Children Mega Capsules Vitogen B Stress C Vit E Zinc & Cop Multiple Vitamins With Iron Tablets Natal-V RX Multi-vitamin/Multi-mineral High Potency Vitamin B Complex + C Tab Multivit with Fluoride P.N. Vitamin-mineral Drink Surbex-500 With Zinc Vitabanks Vitamin Tab V-Natal Corvite Free Fortistress Tab Paramettes Multivits Plus Iron Tab (teens) Multiple Vitamins Plus Iron for Women B 6 Plus Gtf-vitamin-minerals & Pancreatin Tab Harvest Of Values All B Complex Tab Twin G.F. Powder Vanilla Flavor Stress Ctr Srt Multivitamins W Iron Obstetrix DHA Combo Pack Floravit - Syr Senior Multi One Kanga-kid Vitamins & Iron Vitaphil 90 DHA B50 Complex Poly-VI-flor Zatean-Pn Pregvit MultiVitamin with Fluoride Chewable Men's Multi Master Formula Nata Komplete Forty Plus Vitamin Supplement Multiple Vitamin Plus Minerals Tab Men's Biomultiple Vitamin and Mineral Supplement Hylazinc Multi Vitamin & Minerals B-plus - Tab Children Choice Multivitamin W Iron Chew Tab CitraNatal DHA Childrens Chewable Multiple Vitamins Dermamed Nutrition for troubled skin Twin Ultra Liquid Orange Flavor Multi Vite Liq Junior Vitamin B Compound Tab Virt Vite GT Vitaphil DHA Materna-tab Thrivite 19 Genicin Vita-Q FolaMed DHA Flintstones W Extra C Tab SetonET Vitamine Du Groupe B Plus Fer - Liq Enrich Core Pack - Children Vitamin and Mineral Supplement Betaxin Niva-Plus MultiVitamin Drops with Fluoride and Iron Zavitrol Davimet Cda-21 Vitamins With Non-medicinal Probiotic Complex Multivitamin & Minerals (iron Free) Hormodausse Plus Calc Et D Tab Multivitamins and Minerals for Women Stress B&c Tab Stress Tab With Iron and Vitamin E PNV Prenatal Vitamin Children's Multivitamins With Iron Neo-vites & Minerals Tab PreGen DHA Balanced B-50 B-complex Vitamins, Timed Rele Orti B Hi Potency Stress B Tension With C Children's Chewable Multivitamin Complete With Minerals B Complex Tablets B-100 Caps Gesticare DHA Vitaday Junior Tab Prefera OB plus DHA Allbee With Vitamin C Cap Multi Vitamins & Minerals Omniquin One A Day Multiple Vit W Minerals Cavan Alpha Virt-Tabs Duet DHA Supravite Stress Avec Vit E Et Fer Everyday Multiple Vitamins With Iron Vitamin and Mineral Supplement - Liq Concept DHA Formula B Garfield Chewable Multivits Plus Iron Tab Multi-vitamines Enfants Comprime For Kids Only Chewable Multivit. Plus Iron Poly-Vi-Flor Prenatal Vitamins Plus Low Iron tensioSAN Vitachrom Gc B Virol Children's Chewable Vit and Min Tab Virt-Bal DHA Plus Vitamin B Complex + C 600mg Tab Floriva WesNate DHA Childrens Chew Multi Vitamin Tab Ziphex Davimet-M Mega Plex III - Pck Multivitamins and Minerals With Betacarotene Tablets Vitamines Et Mineraux Enfants 970 Multivitamin Drops with Fluoride Synergistic Manganese Cap Neonatal Vitamin Revival 1 Tab Prim - Royal P.M.T. Xyzbac C-Nate DHA Complexe B-75 Multiple Vitamins W Iron Tab Onccor VP-Vite Rx Biovita Sopalamine/3b Tab PNV Prenatal Plus Multivitamin One-A-day Advance Fem - Tablets Vp-heme Ob Cavan Heme OB Moms Choice Rx B Complex With C 300mg Reaphirm Plant Source DHA Dialyvite 5000 Multiple Vitamins Plus Iron Tab Prenate Star Totalvit Plus Tricare Prenatal Quick Dissolve B-50 Complex Tab B-complex Tab One A Day Advance Adults Balanced B 125 Srt NeuroBion Prevital Tab Neo Vites Tab B-plex 100 Virt-Nate Stress B Complex With C, E and Iron Tab B-100 Complex Tablets Integra Plus NataFort Bal-Care DHA Complexe B Compose 75 Flinstones Multiple Plus Iron OB Complete Petite Dialyvite 3000 Multi - N.T.O.x Formula - Tab Gynedyn Tab Nrg Plus Liq Liqui Vita Multiple Vitamins Childrens Chewable Se-Care Conceive Lexazin Sopalamine/3b Plus C Multi-Vitamin With Fluoride Total Living Concepts Formula One - Tab TM-Vite RX Multivitamin with 0.25 mg Fluoride Prenatal Vitamins and Minerals Tablets Fibrik B Complex W C Forte Cap Active OB Multi-force for Women Tab Thiamine HCl Tab 25mg Pro His Mint Multi-kid L-Methyl PNV DHA Multivitamins and Minerals for Men M.V.I. Pediatric Prenara Numark Multivitamins Multi-Vit-Flor Adult Formula 50+ Irospan 24/6 B50 B Complex Tab Formula O.C. PROTECT IRON Liquid RE Nata OB New Chapter's D'adamo 4 Your Type Multiple for Type O Vitamines Pour Bebes Et Enfants Childrens Chewable Vitamin Tab Vasodyn Tab Isotonix Multitech Vitamin Mineral Supplemen Dexatrim Tablets OB Complete 400 Multi Plex I - Tab Soluvit N Prena1 Plus Multi B Somavit Brand Vitamins and Minerals Complex Multi-vitamin Dietary Supplement Palm Springs Multvit and Min Tab E.S.T. Complex Thiamine HCl Tab 50mg Nutrilite Double X Multi-Vitamin Nutrifer Plus Tablets Multivitamines Plus Fer Pour Enfants (chewable Tablets) Prometa Stress B & C Caplet Multiple Vitamins and Minerals Capsules B Complex With C 300mg Tab Multipack II Multi-Vitamin Fluoride Drops Zoo Chews HemeNatal OB Vitamin B Tablets B-complex With Vitamin C, Biotin, Folic Acid Vitafant Vitamin B1 100 mg Vol-Plus Synergistic Manganese Capsules Mvc Kanga-V Multivitamins & Minerals Chewable Multiple Vitamins Plus Extra C Multi-Vitamin with Fluoride Mvc 9+4 Inj Animal Shapes Provida OB Nephrocaps-QT Paramettes Adults Prenatal Vitamins Plus Viva CT Prenatal Folivane-Plus with Ascorbic Acid Precursors Hyporyl - Tab Vita-vim With Beta-carotene - Tab Childrens Chewable Multivitamins W Iron RE Nata WesTab Plus Tendera-OB Vitafol OB Caplet VitaXyme Vitrexyl Multi-12 Pediatric Vitamin B Cpd W Vit C Tab Chewable Multivitamins B-1 Caps 500mg Sun-rype Vitaburst Efferlife Multivitamins and Minerals Materna Multisol Virt-PN Balanced B100 Mega-vim 75 With Beta-carotene - Tablets ahoSAN Vitamin B Complex W C Tab Revit Multi-vitamins and Minerals Foltabs Prenatal Stress Formula + Iron Alkadrenergy Tablets Everyday Multiple Vitamins Supravite C 1000 Hi Potency Balanced B-100 Complex - Tab Super Multi Children's Vitamins Chewable Classic Swiss One 10 Multivitamin and Mineral Tab PR Natal 430 ec Select OB O-Cal Prenatal Vitamin Vitrexate FE Vita Day Tab Beminal 500 Tab Dalivit Multi Plex II - Tab Am Caps B Complex 50 Vitamin Cap Natal PNV Formula Gly B Complex 25mg Vitamin Supplement Viamon Ampoules Et Comprimes Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Alsimine W Vitamins A D Leritone Junior Super Vita-vim With Beta-carotene - Tab Virt-Nate DHA Multiple Vitamins Plus Iron - Tab Multiple Vitamins Tab Vitamin B Complex W C 300mg Tab Multivitamine Multivit Et Fer Ampoules Et Comprimes Mycelized Childrens Multi-vitamin Liq VitaPhil Aide Folika-V Cyroplex Venexa Thiamine Hydrochloride Se-Natal Pregnancy Multivitamin Folic 5 Stress B Complex With C,e, Zinc and Copper Prenatol-M Tricare Prenatal Compleat Vyqua Thiamine HCl 100mg W C 20mg Ventrixyl B 50 Capsules B Vitamin Compound With B12 Thunas Dayavite Allbee With C 550 Cap Children's Multivitamins High Potency Multivitamins & Minerals Caplets Stress Formula Vit B With C Complex Swiss Total One FolaGent DHA Pregvit Folic 5 Multivit-liq M.V.I. Paediatric Chewable Children's Complete Multivitamins With Essential Minerals MultiVitamin, Iron and Fluoride Drops Gemvites Jr Tab Chewable Deriton TriStart DHA Infuvite Adult Vc II Stress Formula Multivitamin Tablets USP Complete One A Day Tab Maxi 6 Liq Enviroflex - Tab Bacmin N.E.U. Complex PreTAB Vitamin B1 Tab 2mg USP WesCap-C-DHA TriphroCaps Duet DHA 400 ec Focalgin 90 DHA B-100 Hi Potency B Vitamins Tab C-force Daily Balance Tab Cc II Hemocyte Plus Vol-Tab Rx Foliflex Phytopure Daily Energy Brand B-complex B-complex Venexa FE Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Luna Vitamin and Mineral Bar for Women Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA PureFe OB Plus Stress B With 1000 Mg Vitamin C Z Bec Tab PreQue 10 Super Kids Chewable Multivitamin Multimineral (chewable Tablets) Tricare Prenatal 2-part Daily Prenatal Vitamin System Children's Chewable Tab Corvita Central-vite 18 Essential Adeks Tablets 24 Multivitamins + Minerals Hemarexin Liquid and Drinkable Ampoules Escavite Lq Nephron FA Usana Megavitamin Tablets - Tab Prenatvite Swiss One Low Potency B Complex Tab Envirocomplex Livita Adults Multivitamin with Fluoride PNV-Select Ultra Hr Chewable Adult Multivitamins With Minerals Formula Fm Vitamins & Minerals Tab Infa Drops Multivitamins Omnivex Vitaday Tab Kanga-B Vitamin B Group + C Multi Vitamin and Fluoride Vyo Cylate - Pwr Multivitamines Et Mineraux Junior Regulier C-B Complex Floriva Plus Se-Natal One Milltrium Senior Vitamin and Mineral Supplement Children's Chewable Multiple Vitamins (chewable Tablets) Hylavite Vitamin B1 100mg Balanced B-50 Complex B-100 Vitamin Supplement Children's Chewable With Iron Vitamine B1 Tab 100mg USP Mebolic Childrens Multiple Vit and Min Chew Tab Multivitamins for Children Beminal With C Fortis Pws Chewable Multiple Vitamins Plus Iron Tab Great Day/am Formula Tab Maintain Multiple Vitamin & Minerals Maximum Once A Day Multinate DHA Vita-worth B-complex Tablets THIAMINE HYDROCHLORIDE injection, solution B Complex Plus C 300mg Tab Formula Lf Neonatal19 Spectrum 2 Cap Iron, Vit & Min Supp Vitafol Plus T.R.I. B-plex Src Se-Plete DHA Vitranol Fe Innersource Tab Multi-vitamins Ribotin-E Trinatal GT Zoo Chews Plus Iron Premium Prenatal Stress Formula Tab Quflora Pediatric Drops Bal-Care DHA Essential Ellis Tonic Multi Spectrum - Tablet Methaver NataChew Multivitamin Vitamines Et Mineraux Only One - Tablet RayaVit L.G.I.T. Kaydia Patch Swiss One Multi Vit & Chel Min Tab Dialyvite Tini-cal Ampoules Elite OB Prenatal Multivitamin Kindervites Gestamine Comprimes Multi Vitamines - Liq Multivitamins and Minerals Tablets Bev 29 Tab Multi Vitamin and Mineral vitamin Virt-Advance Q.T. Vitamin and Mineral Drink Mix Surbex-500 With Iron Poly-Vi-Sol PR Natal 400 Maxine Vitamin and Mineral Supplement Timed Release Vita-vim Srt Phosthenine Vitamines Et Fer (ampoules Buvable) Xvite Folet DHA G.A.S. Complex Penta-thion Pwr Children Choice Multivit Chewable Tab Multi-Vitamin Fluoride Prenatal Formula Tab Ventrixyl Fe Women's Change Formula Multi Rol B Compound 50mg Tab Triveen-Duo DHA VIL-Rx Multi-Vitamin Drops with Fluoride and Iron Vitamine 110 Liq Multi Vitamin Plus Iron Taron-C DHA B Complex W Vit C W Non-med Yeast&liver Tab Multi Vitamin Drops with Fluoride NovaMV Multivitamin Prenatal Vi-min B-Combo Fizz Multivitamins for Kids W C Loz Prenatvite Plus Vp-pnv-dha Virt Nate Pnv-OB-dha Vit B Complex Ctr Super Stress Capsules Complete One-A-day - Tab Phytovim Cap Polymine Avec Zinc Et Cuivre Paramettes Chewable Multivits With Iron Tab RenaPlex Dothelle DHA MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Strovite Forte Caplet Vitaplex Strovite One Caplets Multi-Vit with Fluoride and Iron HemeNatal OB plus DHA Extra Once A Day Revitex Ampoules Et Comprimes Thiamine HCl Injection - Liq 100mg/ml Nutra-Z Trinaz CompleteNate Chewable Fortamines-10 Comprimes Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Essential Vitamins and Minerals Complete Multivitamins and Minerals Tablets Timed Release Floradix Formula Liq
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682