1DKQ

CRYSTAL STRUCTURE OF PHYTATE COMPLEX ESCHERICHIA COLI PHYTASE AT PH 5.0. PHYTATE IS BOUND WITH ITS 3-PHOSPHATE IN THE ACTIVE SITE. HG2+ CATION ACTS AS AN INTERMOLECULAR BRIDGE

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1dkqa_	Alpha and beta proteins (a/b)	Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	Histidine acid phosphatase	Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Histidine acid phosphatase	8019868	4000627	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Histidine phosphatase-like	8032248	3000781	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	His_Phos_2	e1dkqA1	A: a/b three-layered sandwiches	X: Phosphoglycerate mutase-like (From Topology)	H: Phosphoglycerate mutase-like (From Topology)	T: Phosphoglycerate mutase-like	F: His_Phos_2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1240	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Phosphoglycerate mutase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00328	Histidine phosphatase superfamily (branch 2) (His_Phos_2)	Histidine phosphatase superfamily (branch 2)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	PHYTASE	phosphoric ester hydrolase activity nucleotidase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity catalytic activity acid phosphatase activity 4-phytase activity carbohydrate phosphatase activity sugar-phosphatase activity inositol phosphate phosphatase activity pyrophosphatase activity GTPase activity ribonucleoside triphosphate phosphatase activity phosphoric ester hydrolase activity nucleotidase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity catalytic activity acid phosphatase activity 4-phytase activity carbohydrate phosphatase activity sugar-phosphatase activity inositol phosphate phosphatase activity pyrophosphatase activity GTPase activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides	cellular response to stimulus response to decreased oxygen levels response to stimulus cellular response to oxygen levels cellular response to decreased oxygen levels cellular response to anoxia cellular response to chemical stimulus cellular response to stress response to anoxia response to chemical response to stress response to oxygen levels response to abiotic stimulus cellular process cellular response to stimulus response to decreased oxygen levels response to stimulus cellular response to oxygen levels cellular response to decreased oxygen levels cellular response to anoxia cellular response to chemical stimulus cellular response to stress response to anoxia response to chemical response to stress response to oxygen levels response to abiotic stimulus cellular process cellular response to nutrient levels response to nutrient levels cellular response to phosphate starvation response to starvation cellular response to starvation	cellular anatomical structure outer membrane-bounded periplasmic space cell envelope periplasmic space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR000560	Histidine phosphatase superfamily, clade-2	Family
A	IPR029033	Histidine phosphatase superfamily	Homologous Superfamily
A	IPR050645	Histidine Acid Phosphatase	Family
A	IPR033379	Histidine acid phosphatase active site	Active Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.