Annotations: 1GYB

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1gyba_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	NTF2-like	Nuclear transport factor-2 (NTF2)	BAKER'S YEAST (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)
C	d1gybc_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	NTF2-like	Nuclear transport factor-2 (NTF2)	BAKER'S YEAST (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)
D	d1gybd_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	NTF2-like	Nuclear transport factor-2 (NTF2)	BAKER'S YEAST (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)
B	d1gybb_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	NTF2-like	Nuclear transport factor-2 (NTF2)	BAKER'S YEAST (Saccharomyces cerevisiae ) [TaxId: 4932 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	NTF2-like	8039268	3000472	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	NTF2-like	8039268	3000472	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	NTF2-like	8039268	3000472	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	NTF2-like	8039268	3000472	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	NTF2	e1gybA1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: NTF2	ECOD (1.6)
C	NTF2	e1gybC1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: NTF2	ECOD (1.6)
D	NTF2	e1gybD1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: NTF2	ECOD (1.6)
B	NTF2	e1gybB1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: NTF2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.450.50	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
C	3.10.450.50	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
D	3.10.450.50	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
B	3.10.450.50	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF02136	Nuclear transport factor 2 (NTF2) domain (NTF2)	Nuclear transport factor 2 (NTF2) domain	This family includes the NTF2-like Delta-5-3-ketosteroid isomerase proteins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	NUCLEAR TRANSPORT FACTOR 2	small GTPase binding protein binding binding enzyme binding GTPase binding nuclear import signal receptor activity nucleocytoplasmic carrier activity molecular carrier activity	localization cellular localization nucleocytoplasmic transport transport nuclear transport establishment of localization in cell intracellular transport cellular process establishment of localization protein localization establishment of protein localization nitrogen compound transport protein localization to nucleus import into nucleus localization cellular localization nucleocytoplasmic transport transport nuclear transport establishment of localization in cell intracellular transport cellular process establishment of localization protein localization establishment of protein localization nitrogen compound transport protein localization to nucleus import into nucleus establishment of protein localization to organelle protein transport cellular macromolecule localization macromolecule localization protein localization to organelle protein import into nucleus intracellular protein transport	membrane-bounded organelle intracellular organelle organelle envelope cellular anatomical structure intracellular anatomical structure organelle nuclear envelope nucleus intracellular membrane-bounded organelle endomembrane system cytoplasm protein-containing complex nuclear protein-containing complex nuclear pore membrane-bounded organelle intracellular organelle organelle envelope cellular anatomical structure intracellular anatomical structure organelle nuclear envelope nucleus intracellular membrane-bounded organelle endomembrane system cytoplasm protein-containing complex nuclear protein-containing complex nuclear pore nuclear pore central transport channel
E, F, G, H	NUCLEOPORIN	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR032710	NTF2-like domain superfamily	Homologous Superfamily
A, B, C, D	IPR045875	Nuclear transport factor 2	Family
A, B, C, D	IPR002075	Nuclear transport factor 2 domain	Domain
A, B, C, D	IPR018222	Nuclear transport factor 2, eukaryote	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.