E. coli Thymidylate Synthase Bound to dUMP and LY338529, A Pyrrolo(2,3-d)pyrimidine-based Antifolate
External Resource: Annotation
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
A | SCOP2B Superfamily | Thymidylate synthase/dCMP hydroxymethylase | 8041736 | 3000544 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Thymidylate synthase/dCMP hydroxymethylase | 8041736 | 3000544 | SCOP2B (2022-06-29) |
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
A | Thymidylat_synt | e1jutA1 | A: a+b two layers | X: Thymidylate synthase/dCMP hydroxymethylase (From Topology) | H: Thymidylate synthase/dCMP hydroxymethylase (From Topology) | T: Thymidylate synthase/dCMP hydroxymethylase | F: Thymidylat_synt | ECOD (1.6) |
B | Thymidylat_synt | e1jutB1 | A: a+b two layers | X: Thymidylate synthase/dCMP hydroxymethylase (From Topology) | H: Thymidylate synthase/dCMP hydroxymethylase (From Topology) | T: Thymidylate synthase/dCMP hydroxymethylase | F: Thymidylat_synt | ECOD (1.6) |
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|
| THYMIDYLATE SYNTHASE | | | |
Protein Modification Annotation
Modified Residue(s) |
---|
Chain | Residue(s) | Description |
---|
| CXM | Parent Component: MET
RESID:  AA0363 , AA0493
PSI-MOD :  N-carboxy-L-methionine MOD:00368 , N-(dihydroxymethyl)-L-methionine (fMet) MOD:01446 , N-(dihydroxymethyl)-L-methionine (Met) MOD:01447 |