1POI

CRYSTAL STRUCTURE OF GLUTACONATE COENZYME A-TRANSFERASE FROM ACIDAMINOCOCCUS FERMENTANS TO 2.55 ANGSTOMS RESOLUTION

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C	d1poic_	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	CoA transferase alpha subunit-like	Glutaconate:CoA transferase alpha	(Acidaminococcus fermentans ) [TaxId: 905 ],	SCOPe (2.08)
A	d1poia_	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	CoA transferase alpha subunit-like	Glutaconate:CoA transferase alpha	(Acidaminococcus fermentans ) [TaxId: 905 ],	SCOPe (2.08)
B	d1poib_	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	CoA transferase beta subunit-like	Glutaconate:CoA transferase beta	(Acidaminococcus fermentans ) [TaxId: 905 ],	SCOPe (2.08)
D	d1poid_	Alpha and beta proteins (a/b)	NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	CoA transferase beta subunit-like	Glutaconate:CoA transferase beta	(Acidaminococcus fermentans ) [TaxId: 905 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	NagB/RpiA/CoA transferase-like	8032268	3000693	SCOP2B (2022-06-29)
A	SCOP2 Family	CoA transferase alpha subunit-like	8019888	4001854	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	NagB/RpiA/CoA transferase-like	8032268	3000693	SCOP2 (2022-06-29)
B	SCOP2 Family	CoA transferase beta subunit-like	8019889	4001857	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	NagB/RpiA/CoA transferase-like	8032269	3000693	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	NagB/RpiA/CoA transferase-like	8032269	3000693	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	CoA_trans	e1poiC1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: CoA_trans	ECOD (1.6)
A	CoA_trans	e1poiA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: CoA_trans	ECOD (1.6)
B	CoA_trans_1	e1poiB1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: CoA_trans_1	ECOD (1.6)
D	CoA_trans_1	e1poiD1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: CoA_trans_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	3.40.1080.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaconate Coenzyme A-transferase	Glutaconate Coenzyme A-transferase	CATH (4.3.0)
C	3.30.30.40	Alpha Beta	2-Layer Sandwich	Defensin A-like		CATH (4.3.0)
A	3.40.1080.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaconate Coenzyme A-transferase	Glutaconate Coenzyme A-transferase	CATH (4.3.0)
A	3.30.30.40	Alpha Beta	2-Layer Sandwich	Defensin A-like		CATH (4.3.0)
B	3.40.1080.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaconate Coenzyme A-transferase	Glutaconate Coenzyme A-transferase	CATH (4.3.0)
D	3.40.1080.10	Alpha Beta	3-Layer(aba) Sandwich	Glutaconate Coenzyme A-transferase	Glutaconate Coenzyme A-transferase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF01144	Coenzyme A transferase (CoA_trans)	Coenzyme A transferase	-	Domain
B, D	PF01144	Coenzyme A transferase (CoA_trans)	Coenzyme A transferase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	GLUTACONATE COENZYME A-TRANSFERASE	glutaconate CoA-transferase activity transferase activity, transferring sulphur-containing groups transferase activity catalytic activity CoA-transferase activity	catabolic process oxoacid metabolic process energy derivation by oxidation of organic compounds glutamine family amino acid catabolic process glutamate catabolic process via 2-hydroxyglutarate amino acid metabolic process organic acid metabolic process dicarboxylic acid catabolic process organic acid catabolic process alpha-amino acid metabolic process anaerobic glutamate catabolic process fermentation glutamine family amino acid metabolic process cellular catabolic process nitrogenous compound fermentation catabolic process oxoacid metabolic process energy derivation by oxidation of organic compounds glutamine family amino acid catabolic process glutamate catabolic process via 2-hydroxyglutarate amino acid metabolic process organic acid metabolic process dicarboxylic acid catabolic process organic acid catabolic process alpha-amino acid metabolic process anaerobic glutamate catabolic process fermentation glutamine family amino acid metabolic process cellular catabolic process nitrogenous compound fermentation carboxylic acid catabolic process glutamate metabolic process small molecule metabolic process amino acid catabolic process glutamate catabolic process dicarboxylic acid metabolic process carboxylic acid metabolic process L-amino acid catabolic process primary metabolic process generation of precursor metabolites and energy L-amino acid metabolic process anaerobic amino acid catabolic process proteinogenic amino acid metabolic process alpha-amino acid catabolic process proteinogenic amino acid catabolic process metabolic process cellular process small molecule catabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm
B, D	GLUTACONATE COENZYME A-TRANSFERASE	glutaconate CoA-transferase activity transferase activity, transferring sulphur-containing groups transferase activity catalytic activity CoA-transferase activity	catabolic process oxoacid metabolic process energy derivation by oxidation of organic compounds glutamine family amino acid catabolic process glutamate catabolic process via 2-hydroxyglutarate amino acid metabolic process organic acid metabolic process dicarboxylic acid catabolic process organic acid catabolic process alpha-amino acid metabolic process anaerobic glutamate catabolic process fermentation glutamine family amino acid metabolic process cellular catabolic process nitrogenous compound fermentation catabolic process oxoacid metabolic process energy derivation by oxidation of organic compounds glutamine family amino acid catabolic process glutamate catabolic process via 2-hydroxyglutarate amino acid metabolic process organic acid metabolic process dicarboxylic acid catabolic process organic acid catabolic process alpha-amino acid metabolic process anaerobic glutamate catabolic process fermentation glutamine family amino acid metabolic process cellular catabolic process nitrogenous compound fermentation carboxylic acid catabolic process glutamate metabolic process small molecule metabolic process amino acid catabolic process glutamate catabolic process dicarboxylic acid metabolic process carboxylic acid metabolic process L-amino acid catabolic process primary metabolic process generation of precursor metabolites and energy L-amino acid metabolic process anaerobic amino acid catabolic process proteinogenic amino acid metabolic process alpha-amino acid catabolic process proteinogenic amino acid catabolic process metabolic process cellular process small molecule catabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR037171	NagB/RpiA transferase-like	Homologous Superfamily
A, C	IPR004165	Coenzyme A transferase family I	Family
B, D	IPR037171	NagB/RpiA transferase-like	Homologous Superfamily
B, D	IPR004165	Coenzyme A transferase family I	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.