1Y79

Crystal Structure of the E.coli Dipeptidyl Carboxypeptidase Dcp in Complex with a Peptidic Inhibitor

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth 1]	SCOP2 Family	Neurolysin-like	8101530	4001613	SCOP2 (2022-06-29)
A [auth 1]	SCOP2 Superfamily	Metalloproteases (zincins), catalytic domain	8101531	3001975	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth 1]	Peptidase_M3	e1y7911	A: mixed a+b and a/b	X: Zincin-like	H: Metalloproteases (zincins) catalytic domain (From Topology)	T: Metalloproteases (zincins) catalytic domain	F: Peptidase_M3	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth 1]	1.10.1370.40	Mainly Alpha	Orthogonal Bundle	Neurolysin	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth 1]	PF01432	Peptidase family M3 (Peptidase_M3)	Peptidase family M3	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth 1]	Peptidyl-Dipeptidase Dcp	peptidase activity catalytic activity, acting on a protein hydrolase activity exopeptidase activity catalytic activity carboxypeptidase activity cation binding ion binding binding metal ion binding small molecule binding metalloendopeptidase activity metallopeptidase activity endopeptidase activity	proteolysis metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol outer membrane-bounded periplasmic space cell envelope periplasmic space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth 1]	IPR024079	Metallopeptidase, catalytic domain superfamily	Homologous Superfamily
A [auth 1]	IPR001567	Peptidase M3A/M3B catalytic domain	Domain
A [auth 1]	IPR034005	Peptidyl-dipeptidase DCP	Family
A [auth 1]	IPR024077	Neurolysin/Thimet oligopeptidase, domain 2	Homologous Superfamily
A [auth 1]	IPR045090	Peptidase M3A/M3B	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.