3A0K

Crystal structure of an antiflamatory legume lectin from Cymbosema roseum seeds

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3a0ka_	All beta proteins	Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	Legume lectins	automated matches	(Cymbosema roseum ) [TaxId: 202239 ],	SCOPe (2.08)
B [auth C]	d3a0kc_	All beta proteins	Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	Legume lectins	automated matches	(Cymbosema roseum ) [TaxId: 202239 ],	SCOPe (2.08)
C [auth E]	d3a0ke_	All beta proteins	Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	Legume lectins	automated matches	(Cymbosema roseum ) [TaxId: 202239 ],	SCOPe (2.08)
D [auth G]	d3a0kg_	All beta proteins	Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	Legume lectins	automated matches	(Cymbosema roseum ) [TaxId: 202239 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Legume lectins	8073911	4000327	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Concanavalin A-like lectins/glucanases	8073912	3000120	SCOP2 (2022-06-29)
B [auth C]	SCOP2B Superfamily	Concanavalin A-like lectins/glucanases	8073912	3000120	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	Concanavalin A-like lectins/glucanases	8073912	3000120	SCOP2B (2022-06-29)
D [auth G]	SCOP2B Superfamily	Concanavalin A-like lectins/glucanases	8073912	3000120	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Lectin_legB	e3a0kA1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Concanavalin A-like lectins/glucanases	F: Lectin_legB	ECOD (1.6)
B [auth C]	Lectin_legB	e3a0kC1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Concanavalin A-like lectins/glucanases	F: Lectin_legB	ECOD (1.6)
C [auth E]	Lectin_legB	e3a0kE1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Concanavalin A-like lectins/glucanases	F: Lectin_legB	ECOD (1.6)
D [auth G]	Lectin_legB	e3a0kG1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Concanavalin A-like lectins/glucanases	F: Lectin_legB	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.120.200	Mainly Beta	Sandwich	Jelly Rolls		CATH (4.3.0)
B [auth C]	2.60.120.200	Mainly Beta	Sandwich	Jelly Rolls		CATH (4.3.0)
C [auth E]	2.60.120.200	Mainly Beta	Sandwich	Jelly Rolls		CATH (4.3.0)
D [auth G]	2.60.120.200	Mainly Beta	Sandwich	Jelly Rolls		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B [auth C], C [auth E], D [auth G]	PF00139	Legume lectin domain (Lectin_legB)	Legume lectin domain		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B [auth C], C [auth E], D [auth G]	Cymbosema roseum mannose-specific lectin	binding carbohydrate binding cation binding ion binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B [auth C], C [auth E], D [auth G]	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	Homologous Superfamily
A, B [auth C], C [auth E], D [auth G]	IPR001220	Legume lectin domain	Domain
A, B [auth C], C [auth E], D [auth G]	IPR000985	Legume lectin, alpha chain, conserved site	Conserved Site
A, B [auth C], C [auth E], D [auth G]	IPR050258	Leguminous Lectin	Family
A, B [auth C], C [auth E], D [auth G]	IPR019825	Legume lectin, beta chain, Mn/Ca-binding site	Binding Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.