4LK6

Crystal Structure of Pseudomonas aeruginosa Lectin LecA Complexed with Chlorophenol Red-b-D-galactopyranoside at 2.86 A Resolution

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4lk6a_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
B	d4lk6b_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
C	d4lk6c_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
D	d4lk6d_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
F	d4lk6f_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
G	d4lk6g_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
H	d4lk6h_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
I	d4lk6i_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
K	d4lk6k_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
L	d4lk6l_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
E	d4lk6e_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
J	d4lk6j_	All beta proteins	Galactose-binding domain-like	Galactose-binding domain-like	PA-IL, galactose-binding lectin 1	PA-IL, galactose-binding lectin 1	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PA-IL	e4lk6A1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
B	PA-IL	e4lk6B1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
C	PA-IL	e4lk6C1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
D	PA-IL	e4lk6D1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
F	PA-IL	e4lk6F1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
G	PA-IL	e4lk6G1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
H	PA-IL	e4lk6H1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
I	PA-IL	e4lk6I1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
K	PA-IL	e4lk6K1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
L	PA-IL	e4lk6L1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
E	PA-IL	e4lk6E1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
J	PA-IL	e4lk6J1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
B	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
C	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
D	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
F	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
G	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
H	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
I	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
K	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
L	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
E	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
J	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF07828	PA-IL-like protein (PA-IL)	PA-IL-like protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PA-I galactophilic lectin	binding carbohydrate binding	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules cell adhesion cell-cell adhesion cellular process cell-cell adhesion via plasma-membrane adhesion molecules	cell surface cellular anatomical structure periplasmic space intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR012905	PA-IL-like	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR008979	Galactose-binding-like domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.