6BUQ | pdb_00006buq

Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica complexed with barbituric acid

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6buqa_	Alpha and beta proteins (a+b)	Bacillus chorismate mutase-like	YjgF-like	Amidohydrolase ring-opening protein-like	automated matches	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
B	d6buqb1	Alpha and beta proteins (a+b)	Bacillus chorismate mutase-like	YjgF-like	Amidohydrolase ring-opening protein-like	automated matches	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
B	d6buqb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
C	d6buqc_	Alpha and beta proteins (a+b)	Bacillus chorismate mutase-like	YjgF-like	Amidohydrolase ring-opening protein-like	automated matches	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)
D	d6buqd_	Alpha and beta proteins (a+b)	Bacillus chorismate mutase-like	YjgF-like	Amidohydrolase ring-opening protein-like	automated matches	(Moorella thermoacetica ATCC 39073 ) [TaxId: 264732 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Amido_AtzD_TrzD_1st	e6buqA1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_1st	ECOD (1.6)
A	Amido_AtzD_TrzD_2nd	e6buqA3	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_2nd	ECOD (1.6)
A	Amido_AtzD_TrzD_3rd	e6buqA2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_3rd	ECOD (1.6)
B	Amido_AtzD_TrzD_1st	e6buqB3	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_1st	ECOD (1.6)
B	Amido_AtzD_TrzD_2nd	e6buqB2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_2nd	ECOD (1.6)
B	Amido_AtzD_TrzD_3rd	e6buqB1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_3rd	ECOD (1.6)
C	Amido_AtzD_TrzD_1st	e6buqC3	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_1st	ECOD (1.6)
C	Amido_AtzD_TrzD_2nd	e6buqC1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_2nd	ECOD (1.6)
C	Amido_AtzD_TrzD_3rd	e6buqC2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_3rd	ECOD (1.6)
D	Amido_AtzD_TrzD_1st	e6buqD1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_1st	ECOD (1.6)
D	Amido_AtzD_TrzD_2nd	e6buqD2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_2nd	ECOD (1.6)
D	Amido_AtzD_TrzD_3rd	e6buqD3	A: a+b three layers	X: Bacillus chorismate mutase-like	H: YjgF-like (From Topology)	T: YjgF-like	F: Amido_AtzD_TrzD_3rd	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.1330.170	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
A	3.30.1330.160	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
B	3.30.1330.170	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
B	3.30.1330.160	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
C	3.30.1330.170	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
C	3.30.1330.160	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
D	3.30.1330.170	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)
D	3.30.1330.160	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF09663	Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) (Amido_AtzD_TrzD)	Amidohydrolase ring-opening protein (Amido_AtzD_TrzD)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Cyanuric acid amidohydrolase	hydrolase activity cyanuric acid amidohydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides catalytic activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds cation binding ion binding binding metal ion binding small molecule binding	cellular response to stimulus catabolic process response to stimulus atrazine metabolic process cellular response to xenobiotic stimulus polyamine metabolic process s-triazine compound catabolic process xenobiotic catabolic process biogenic amine catabolic process xenobiotic metabolic process response to xenobiotic stimulus amine metabolic process cellular response to chemical stimulus organohalogen metabolic process s-triazine compound metabolic process cellular response to stimulus catabolic process response to stimulus atrazine metabolic process cellular response to xenobiotic stimulus polyamine metabolic process s-triazine compound catabolic process xenobiotic catabolic process biogenic amine catabolic process xenobiotic metabolic process response to xenobiotic stimulus amine metabolic process cellular response to chemical stimulus organohalogen metabolic process s-triazine compound metabolic process response to chemical atrazine catabolic process metabolic process cellular process polyamine catabolic process biogenic amine metabolic process amine catabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR043006	Cyanuric acid hydrolase/Barbiturase, repeating unit B	Homologous Superfamily
A, B, C, D	IPR043007	Cyanuric acid hydrolase/Barbiturase, repeating unit C	Homologous Superfamily
A, B, C, D	IPR014086	Cyanuric acid hydrolase/Barbiturase	Family
A, B, C, D	IPR043008	Cyanuric acid hydrolase/Barbiturase, repeating unit A	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.