8BK2
X-ray structure of meningococcal factor H binding protein variant 2 in complex with a specific and bactericidal human monoclonal antibody 1B1
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
D [auth H], F [auth D], H [auth F] | Heavy Chain | IGHV3 | - | factor h-binding protein | SAbDab (2024-11-15) |
E [auth L], G [auth E], I [auth G] | Light Chain | IGKV3 | Kappa | factor h-binding protein | SAbDab (2024-11-15) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF08794 | Factor H binding protein, C-terminal (FHBP_C) | Factor H binding protein, C-terminal | Factor H binding protein (also known as GNA1870) is a surface exposed lipoprotein in Neisseria meningitidis that is a potent antigen and a potential candidate for a vaccine against meningococcal disease [1-4]. The structure of the C-terminal domain c ... | Domain | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
Factor H-binding protein | - | - | ||
D [auth H], F [auth D], H [auth F] | Fab Heavy chain | - | - | - |
E [auth L], G [auth E], I [auth G] | Fab light Chains | - | - | - |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR011250 | Outer membrane protein/outer membrane enzyme PagP, beta-barrel | Homologous Superfamily | |
IPR014902 | Factor H binding protein-like, C-terminal | Domain | |
IPR049377 | Factor H binding protein, N-terminal | Domain | |
IPR049378 | Factor H binding protein | Family |