8RDE

STRUCTURE OF THE MOUSE FCGBP DIMER PROTEIN IN ITS COMPACT CONFORMATION

External Resource: Annotation

Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B [auth D]	PF08742	C8 domain (C8)	C8 domain	This domain contains 8 conserved cysteine residues, but this family only contains 7 of them to overlaps with other domains. It is found in disease-related proteins including von Willebrand factor, Alpha tectorin, Zonadhesin and Mucin. It is often fo ...	This domain contains 8 conserved cysteine residues, but this family only contains 7 of them to overlaps with other domains. It is found in disease-related proteins including von Willebrand factor, Alpha tectorin, Zonadhesin and Mucin. It is often found on proteins containing Pfam:PF00094 and Pfam:PF01826.	Domain
A, B [auth D]	PF01826	Trypsin Inhibitor like cysteine rich domain (TIL)	Trypsin Inhibitor like cysteine rich domain	This family contains trypsin inhibitors as well as a domain found in many extracellular proteins. The domain typically contains ten cysteine residues that form five disulphide bonds. The cysteine residues that form the disulphide bonds are 1-7, 2-6, ...	This family contains trypsin inhibitors as well as a domain found in many extracellular proteins. The domain typically contains ten cysteine residues that form five disulphide bonds. The cysteine residues that form the disulphide bonds are 1-7, 2-6, 3-5, 4-10 and 8-9.	Domain
A, B [auth D]	PF00094	von Willebrand factor type D domain (VWD)	von Willebrand factor type D domain	Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods. This domain is structurally homologous to the C-terminal domain of repulsive guidance molecules (RGM) despite low sequence identity [2 ...	Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods. This domain is structurally homologous to the C-terminal domain of repulsive guidance molecules (RGM) despite low sequence identity [2].	Domain
A, B [auth D]	PF12714	TILa domain (TILa)	TILa domain	This cysteine rich domain occurs along side the TIL Pfam:PF01826 domain and is likely to be a distantly related relative.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B [auth D]	Fc fragment of IgG binding protein	-	-	cell periphery extracellular matrix cellular anatomical structure external encapsulating structure

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B [auth D]	IPR036084	Serine protease inhibitor-like superfamily	Homologous Superfamily
A, B [auth D]	IPR025615	TILa domain	Domain
A, B [auth D]	IPR003645	Follistatin-like, N-terminal	Domain
A, B [auth D]	IPR002919	Trypsin Inhibitor-like, cysteine rich domain	Domain
A, B [auth D]	IPR001007	VWFC domain	Domain
A, B [auth D]	IPR001846	von Willebrand factor, type D domain	Domain
A, B [auth D]	IPR052749	Alpha-tectorin	Family
A, B [auth D]	IPR014853	VWF/SSPO/Zonadhesin-like, cysteine-rich domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.