8W3Z | pdb_00008w3z

Crystal structure of a computationally designed metalloprotein containing the metal-chelating, fluorogenic, non-canonical amino acid 3-(8-hydroxyquinolin-3-yl)-L-alanine: magnesium-bound form

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Ribulose-phoshate binding barrel	8043259	3000216	SCOP2B (2022-06-29)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Hydroxyquinoline fluorescent protein	indole-3-glycerol-phosphate synthase activity carboxy-lyase activity lyase activity catalytic activity carbon-carbon lyase activity phosphoribosylanthranilate isomerase activity isomerase activity intramolecular oxidoreductase activity, interconverting aldoses and ketoses intramolecular oxidoreductase activity	oxoacid metabolic process indole-containing compound metabolic process amino acid metabolic process organic acid biosynthetic process organic acid metabolic process alpha-amino acid metabolic process carboxylic acid biosynthetic process biogenic amine biosynthetic process indole-containing compound biosynthetic process L-tryptophan metabolic process indolalkylamine metabolic process small molecule metabolic process erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process indolalkylamine biosynthetic process oxoacid metabolic process indole-containing compound metabolic process amino acid metabolic process organic acid biosynthetic process organic acid metabolic process alpha-amino acid metabolic process carboxylic acid biosynthetic process biogenic amine biosynthetic process indole-containing compound biosynthetic process L-tryptophan metabolic process indolalkylamine metabolic process small molecule metabolic process erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process indolalkylamine biosynthetic process aromatic amino acid family biosynthetic process aromatic amino acid metabolic process small molecule biosynthetic process carboxylic acid metabolic process primary metabolic process L-amino acid biosynthetic process L-amino acid metabolic process L-tryptophan biosynthetic process proteinogenic amino acid metabolic process amine metabolic process amino acid biosynthetic process biosynthetic process amine biosynthetic process proteinogenic amino acid biosynthetic process metabolic process cellular process erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process biogenic amine metabolic process alpha-amino acid biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR013798	Indole-3-glycerol phosphate synthase domain	Domain
A	IPR011060	Ribulose-phosphate binding barrel	Homologous Superfamily
A	IPR001468	Indole-3-glycerol phosphate synthase, conserved site	Conserved Site
A	IPR013785	Aldolase-type TIM barrel	Homologous Superfamily
A	IPR045186	Indole-3-glycerol phosphate synthase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.