Annotations: 9AWE

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C [auth A]	SCOP2B Superfamily	ASF1-like	8055363	3002057	SCOP2B (2022-06-29)
D [auth C]	SCOP2B Superfamily	Immunoglobulin-binding domains-like	8072912	3000399	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C [auth A]	PF04729	ASF1 like histone chaperone (ASF1_hist_chap)	ASF1 like histone chaperone	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth B]	Fab Heavy Chain	-	-	-
B [auth D]	Fab Light Chain	-	-	-
C [auth A]	Histone chaperone ASF1	protein binding binding histone binding enzyme regulator activity enzyme activator activity molecular function activator activity acetyltransferase activator activity molecular function regulator activity	cellular response to stimulus cellular response to stress response to stimulus response to stress cellular process protein-containing complex organization protein-DNA complex assembly cellular component organization protein-DNA complex organization cellular component biogenesis cellular component assembly chromatin organization protein-containing complex assembly chromatin remodeling cellular response to stimulus cellular response to stress response to stimulus response to stress cellular process protein-containing complex organization protein-DNA complex assembly cellular component organization protein-DNA complex organization cellular component biogenesis cellular component assembly chromatin organization protein-containing complex assembly chromatin remodeling cellular component organization or biogenesis nucleosome assembly nucleosome organization regulation of cellular process regulation of cell cycle phase transition negative regulation of biological process regulation of cellular response to stress negative regulation of cell cycle regulation of signal transduction intracellular signal transduction cell communication regulation of cell cycle checkpoint negative regulation of cell cycle phase transition signal transduction cell cycle regulation of biological process regulation of cell cycle process DNA integrity checkpoint signaling regulation of response to stimulus negative regulation of DNA damage checkpoint negative regulation of cell cycle checkpoint DNA damage checkpoint signaling signaling negative regulation of signaling negative regulation of intracellular signal transduction positive regulation of biological process cell cycle phase transition negative regulation of cell communication regulation of intracellular signal transduction regulation of response to stress negative regulation of cellular process positive regulation of cell cycle process regulation of cell cycle positive regulation of cellular process cell cycle process regulation of signaling negative regulation of response to stimulus biological regulation negative regulation of cell cycle process negative regulation of signal transduction positive regulation of cell cycle cell cycle checkpoint signaling DNA damage response positive regulation of cell cycle phase transition signal transduction in response to DNA damage regulation of cell communication regulation of DNA damage checkpoint macromolecule modification metabolic process primary metabolic process protein metabolic process macromolecule metabolic process protein modification process subtelomeric heterochromatin formation negative regulation of macromolecule metabolic process regulation of biosynthetic process heterochromatin formation epigenetic regulation of gene expression negative regulation of metabolic process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process regulation of gene expression negative regulation of gene expression constitutive heterochromatin formation biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process negative regulation of gene expression, epigenetic regulation of macromolecule biosynthetic process regulation of metabolic process DNA replication-dependent chromatin assembly RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process transcription by RNA polymerase II regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of transcription by RNA polymerase II nucleobase-containing compound biosynthetic process nucleic acid metabolic process regulation of DNA-templated transcription silent mating-type cassette heterochromatin formation transcription elongation by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription elongation by RNA polymerase II positive regulation of macromolecule biosynthetic process positive regulation of metabolic process positive regulation of biosynthetic process positive regulation of DNA-templated transcription, elongation positive regulation of macromolecule metabolic process regulation of DNA-templated transcription elongation positive regulation of nucleobase-containing compound metabolic process regulation of transcription elongation by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of RNA metabolic process DNA-templated transcription elongation positive regulation of RNA biosynthetic process cellular component disassembly protein-DNA complex disassembly protein-containing complex disassembly nucleosome disassembly DNA repair DNA metabolic process regulation of DNA repair regulation of DNA metabolic process	protein-containing complex intracellular anatomical structure catalytic complex intracellular membraneless organelle chromatin chromosome transferase complex H3 histone acetyltransferase complex histone acetyltransferase complex acetyltransferase complex intracellular organelle cellular anatomical structure organelle membraneless organelle protein-containing complex intracellular anatomical structure catalytic complex intracellular membraneless organelle chromatin chromosome transferase complex H3 histone acetyltransferase complex histone acetyltransferase complex acetyltransferase complex intracellular organelle cellular anatomical structure organelle membraneless organelle protein acetyltransferase complex intracellular protein-containing complex cytoplasm cytosol chromosome, telomeric region chromosomal region membrane-bounded organelle nucleus intracellular membrane-bounded organelle
D [auth C]	Immunoglobulin G-binding protein G	protein-containing complex binding binding immunoglobulin binding IgG binding	-	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C [auth A]	IPR017282	Histone deposition protein Asf1	Family
C [auth A]	IPR036747	Histone chaperone ASF1-like superfamily	Homologous Superfamily
C [auth A]	IPR006818	Histone chaperone ASF1-like	Family
D [auth C]	IPR009063	Immunoglobulin/albumin-binding domain superfamily	Homologous Superfamily
D [auth C]	IPR019950	M protein-type anchor domain	Domain
D [auth C]	IPR005877	YSIRK Gram-positive signal peptide	Domain
D [auth C]	IPR000724	IgG-binding B	Domain
D [auth C]	IPR035152	GA-like domain	Domain
D [auth C]	IPR019931	LPXTG cell wall anchor domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.