9QPR | pdb_00009qpr

Single particle cryo-EM structure of the multidrug efflux pump MdtF from Escherichia coli

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C], B [auth A], C [auth B]	Multidrug resistance protein MdtF	lipid transporter activity lipid transmembrane transporter activity transporter activity monocarboxylic acid transmembrane transporter activity carboxylic acid transmembrane transporter activity organic acid transmembrane transporter activity transmembrane transporter activity organic anion transmembrane transporter activity bile acid transmembrane transporter activity efflux transmembrane transporter activity xenobiotic transmembrane transporter activity identical protein binding protein binding binding	response to stimulus response to chemical response to antibiotic localization xenobiotic transport transport establishment of localization transmembrane transport xenobiotic transmembrane transport cellular process response to toxic substance organic anion transport carboxylic acid transport lipid localization response to stimulus response to chemical response to antibiotic localization xenobiotic transport transport establishment of localization transmembrane transport xenobiotic transmembrane transport cellular process response to toxic substance organic anion transport carboxylic acid transport lipid localization bile acid and bile salt transport lipid transport organic hydroxy compound transport organic acid transport monocarboxylic acid transport macromolecule localization	cellular anatomical structure membrane cell periphery plasma membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth C], B [auth A], C [auth B]	IPR027463	Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains	Homologous Superfamily
A [auth C], B [auth A], C [auth B]	IPR001036	Acriflavin resistance protein	Family
A [auth C], B [auth A], C [auth B]	IPR004764	Multidrug resistance protein MdtF-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.