5GP
GUANOSINE-5'-MONOPHOSPHATE
Find entries where: 5GP
is present as a standalone ligand in 163 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 21 entries
is present in a polymer sequence 4 entries
Chemical Component Summary | |
|---|---|
| Name | GUANOSINE-5'-MONOPHOSPHATE |
| Identifiers | [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate |
| Formula | C10 H14 N5 O8 P |
| Molecular Weight | 363.221 |
| Type | NON-POLYMER |
| Isomeric SMILES | c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N=C(NC2=O)N |
| InChI | InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1 |
| InChIKey | RQFCJASXJCIDSX-UUOKFMHZSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 38 |
| Chiral Atom Count | 4 |
| Bond Count | 40 |
| Aromatic Bond Count | 5 |
Drug Info: DrugBank
| DrugBank ID | DB01972? |
|---|---|
| Name | Guanosine-5'-Monophosphate |
| Groups | experimental |
| Description | Guanosine 5'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. [PubChem] |
| Synonyms | Guanosine-5'-Monophosphate |
| CAS number | 85-32-5 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Guanylate kinase | MSGPRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENG... | unknown | |
| Response regulator PleD | MSARILVVDDIEANVRLLEAKLTAEYYEVSTAMDGPTALAMAARDLPDII... | unknown | |
| DNA polymerase | MKEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYF... | unknown | |
| Disks large homolog 4 | MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGY... | unknown | |
| GMP reductase 1 | MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPI... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 5280325, 6804, 135398631 |
| ChEMBL | CHEMBL283807 |
| ChEBI | CHEBI:17345 |
