5UD

5-FLUOROURIDINE

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is present as a standalone ligand in 4 entries

is present in a polymer sequence 1 entries

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Chemical Component Summary
Name	5-FLUOROURIDINE
Identifiers	1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-pyrimidine-2,4-dione
Formula	C₉ H₁₁ F N₂ O₆
Molecular Weight	262.192
Type	NON-POLYMER
Isomeric SMILES	C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)F
InChI	InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChIKey	FHIDNBAQOFJWCA-UAKXSSHOSA-N

Chemical Details
Formal Charge	0
Atom Count	29
Chiral Atom Count	4
Bond Count	30
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB01629 ?
Name	5-fluorouridine
Groups	experimental
Description	5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine base attached to a sugar. 5-fluorouridine is known to target uridine phosphorylase. FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.
Synonyms	5-Fluorouracil 1beta-D-ribofuranoside 5-fluorouridine 5-Fur 5-Fluoro-uridine
Categories	Fluorouracil and prodrugs Nucleic Acids, Nucleotides, and Nucleosides Nucleosides Pyrimidine Nucleosides Pyrimidines Ribonucleosides Thyroxine-binding globulin inducers
CAS number	316-46-1

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Superoxide dismutase [Cu-Zn]	MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHE...	unknown
Uridine phosphorylase	MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLAShref...	unknown
Thyroxine-binding globulin	MSPFLYLVLLVLGLHATIHCASPEGKVTACHSSQPNATLYKMSSINADFA...	unknown	inducer

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682