ACH
ACETYLCHOLINE
Find entries where: ACH
is present as a standalone ligand in 23 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 1 entries
Chemical Component Summary | |
|---|---|
| Name | ACETYLCHOLINE |
| Identifiers | 2-acetyloxyethyl-trimethyl-azanium |
| Formula | C7 H16 N O2 |
| Molecular Weight | 146.207 |
| Type | NON-POLYMER |
| Isomeric SMILES | CC(=O)OCC[N+](C)(C)C |
| InChI | InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1 |
| InChIKey | OIPILFWXSMYKGL-UHFFFAOYSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 1 |
| Atom Count | 26 |
| Chiral Atom Count | 0 |
| Bond Count | 25 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB03128? |
|---|---|
| Name | Acetylcholine |
| Groups |
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| Description | A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, but it is useful in some ophthalmological applications. |
| Synonyms |
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| Brand Names |
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| Indication | Used to obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. |
| Categories |
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| ATC-Code | S01EB09 |
| CAS number | 51-84-3 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISF... | unknown | |
| Muscarinic acetylcholine receptor M2 | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKV... | unknown | |
| Muscarinic acetylcholine receptor M3 | MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFS... | unknown | |
| Muscarinic acetylcholine receptor M4 | MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGN... | unknown | |
| Neuronal acetylcholine receptor subunit alpha-7 | MRCSPGGVWLALAASLLHVSLQGEFQRKLYKELVKNYNPLERPVANDSQP... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL667 |
| PubChem | 187 |
| ChEMBL | CHEMBL667 |
| ChEBI | CHEBI:15355 |
| CCDC/CSD | ACHOLC01, ACTART11, JOKROS, ACCHOB11, GEBMEF, ACHTPB, IXOYIF, UVIYUW |
