AIC

(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID

Find entries where: AIC

is present as a standalone ligand in 8 entries

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Chemical Component Summary
Name	(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
Synonyms	AMPICILLIN; D(-)-ALPHA-AMINOBENZYLPENICILLIN; 6-[D(-)-ALPHA-AMINOPHENYLLACETAMIDO]PENICILLANIC ACID
Identifiers	(2S,5R,6R)-6-[[(2R)-2-amino-2-phenyl-ethanoyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Formula	C₁₆ H₁₉ N₃ O₄ S
Molecular Weight	349.405
Type	NON-POLYMER
Isomeric SMILES	CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](c3ccccc3)N)C(=O)O)C
InChI	InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1
InChIKey	AVKUERGKIZMTKX-NJBDSQKTSA-N

Chemical Details
Formal Charge	0
Atom Count	43
Chiral Atom Count	4
Bond Count	45
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB00415 ?
Name	Ampicillin
Groups	approved vet_approved
Description	Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Synonyms	Ampicilline Ampicillin sodium D-(?)-ampicillin Ampicillin acid Ampicillin (anhydrous) D-(?)-6-(α-aminophenylacetamido)penicillanic acid Anhydrous ampicillin AP Aminobenzylpenicillin Ampicilina Ampicillin, anhydrous Ampicillin trihydrate ABPC Ampicillin anhydrous Ampicillinum Ampicillin
Brand Names	Jaa Amp Tab 125mg Penbritin-1000 Pws 1000mg/vial Ampicin Inj 2000mg Penbritin Inj 2000mg Ampicillin Sodium for Injection, USP Ampicin Inj 1gm Penbritin Pws 250mg/5ml Penbritin Inj 250mg Apo Ampi Liq 125mg/5ml Nu-ampi Capsules 500mg AMPICILLIN and SULBACTAM Penbritin Cap 250mg Apo Ampi Capsules 500mg Ampicillin Sodium and Sulbactam Sodium Ampicillin Ampicillin Sodium Penbritin Cap 500mg Unasyn Novo-ampicillin Pws 500mg/5ml Ampicillin and Sulbactam Pro Biosan Kit Penbritin-125 Pws 125mg/vial Sterile Ampicillin Sodium 250mg USP Ampicin Inj 125mg/vial Ampicillin Sodium for Injection, BP Ampicin for Injection 250mg Ampicin Inj 500mg Nu-ampi Sus 125mg/5ml Pro Ampi 500 Cap 500mg Taro-ampicillin Cap 500mg Nu-ampi Suspension 250mg/5ml Novo-ampicillin Sus 125mg/5ml Teva-ampicillin Novo-ampicillin Sus 250mg/5ml Ampicillin Sodium for Injection BP Penbritin-250 Pws Im/iv 250mg/vial Ampicillin for Injection, USP Ampicillin for Injection Penbritin Inj 500mg Penbritin Inj 1000mg Apo Ampi Liq 250mg/5ml Pro Ampi 250 Cap 250mg Ampicillin sodium Ampicillin Trihydrate Taro-ampicillin Cap 250mg Nu-ampi Capsules 250mg Apo Ampi Capsules 250mg
Indication	For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc
Categories	Amides Aminopenicillins Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Beta-Lactam Antibacterials beta-Lactams Drugs that are Mainly Renally Excreted Heterocyclic Compounds, Fused-Ring Lactams Ophthalmologicals Penicillin G Penicillins Penicillins With Extended Spectrum Sensory Organs Sulfur Compounds
ATC-Code	J01CR50 J01CA51 J01CA01 S01AA19
CAS number	69-53-4

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Penicillin-binding protein 2a	MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGPIRKFWR...	unknown	inhibitor
Penicillin-binding protein 1b	MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKSAIFPAI...	unknown	inhibitor
Penicillin-binding protein 3	MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILYEKDATQ...	unknown	inhibitor
Penicillin-binding protein 1A	MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSESKLVAT...	unknown	inhibitor
Penicillin-binding protein 2B	MRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNKDFYEKKLASAS...	unknown	inhibitor
Solute carrier family 15 member 1	MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDN...	unknown
Solute carrier family 15 member 2	MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIV...	unknown
Angiopoietin-1 receptor	MDSLASLVLCGVSLLLSGTVEGAMDLILINSLPLVSDAETSLTCIASGWR...	unknown
Serum albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	other/unknown
Solute carrier family 22 member 5	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Solute carrier family 15 member 1	MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDN...	unknown	inhibitor
Solute carrier family 15 member 2	MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIV...	unknown	inhibitor
Monocarboxylate transporter 1	MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGI...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682