AIN

2-(ACETYLOXY)BENZOIC ACID

Created:	2004-04-08
Last modified:	2020-05-26

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8 entries where AIN is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	21
Chiral Atom Count	0
Bond Count	21
Aromatic Bond Count	6

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Chemical Component Summary
Name	2-(ACETYLOXY)BENZOIC ACID
Synonyms	ACETYLSALICYLIC ACID; ASPIRIN
Systematic Name (OpenEye OEToolkits)	2-acetyloxybenzoic acid
Formula	C₉ H₈ O₄
Molecular Weight	180.157
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(Oc1ccccc1C(=O)O)C
SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
Canonical SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
InChI	InChI	1.03	InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
InChIKey	InChI	1.03	BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00945 ?
Name	Acetylsalicylic acid
Groups	vet_approved approved
Description	Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
Synonyms	Aspirin ASA o-carboxyphenyl acetate Acetylsalicylic acid Azetylsalizyls?ure 2-Acetoxybenzenecarboxylic acid Salicylic acid acetate Acidum acetylsalicylicum Acide acétylsalicylique Acetylsalicyls?ure Lysine acetylsalicylate Acetylsalicylate o-acetoxybenzoic acid O-acetylsalicylic acid Polopiryna ácido acetilsalicílico acide 2-(acétyloxy)benzo?que 2-Acetoxybenzoic acid Aspirina
Brand Names	Ana-dent Hydrocodone Bitartrate and Aspirin Basic Care Headache Relief Fiorinal-C 1/4 Anacin Extra Strength GENUINE FIRST AID Emergency Preparedness Contains 167 PIECES HARDCASE ENTERIC COATED ASPIRIN Regular Strength Mountain Series Weekender Medical Plus Pharma NSAID Aspirin Pain Away Plus 4225 First Aid Kit Asa Tablets USP 325 mg Circle K Headache Relief Low Dose Aspirin Chewable SohMed Pain Reliever Leader Cardinal Health Aspirin Goodys Cool Orange Headache Up and Up Antacid and Pain Relief Entrophen 650mg Caplet Ect Sedal3x Bc Coricidin Tab Leader migraine formula CVS All Purpose First Aid Kit Halfprin Low Dose Aspirin Asa 325 Mg Tablets Regular Strength Aspirin Extra Strength Plus Kirkland Signature Migraine Relief TopCare Effervescent Antacid and Pain Relief pain relief back and body EXTRA STRENGTH Zee Pain Aid HEALTH SENSE Adult Chewable Low Strength Aspirin Asadol 650mg PhysiciansCare Extra Stregth Pain Reliever Aspirin Low Dose Sound Body Migraine Relief Chewable Low Dose Aspirin Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy Aspirin Thin coated Butalbital Compound FIRST AID Contains 101 PIECES Bayer Genuine Aspirin Coated Aspirin - Ect 80mg Alka-Seltzer Plus Night Cold Medicine Dg Health Headache Relief Coricidin D Tab Coryphen 650 Codeine 30 Tab Quality Choice Effervescent Antacid and Pain Relief Chewable Low Dose Leader Low Dose Aspirin Norgesic Tab Muscle and Back Pain Relief Extra Strength St. Joseph Chewable Aspirin Aspirin Coated Caplets 500mg Lil Drug Store Headache Relief Extra Strength Artrifin 24 Caplets Miniprin Ru-21 Hangover Relief Instantine Tab Leader Extra Strength Effervescent Antacid and Pain Reliever Green Guard Tri Buffered Aspirin relief Teva-tecnal Blowfish 4214 First Aid Kit Asa Chewable Tablets Zee Aspirin Pain Relief Fast Relief Bayer Advanced Aspirin Extra Strength Caring Mill Aspirin 7 Select Aspirin A.C. & C. 8mg Genuine First Aid Industrial First Aid Smart Sense Chewable Aspirin Good Sense Headache Relief Biovanta Trip Action Green Apple and Honey Goodys PM Pain Reliever 282 Tab Excedrin Back and Body 4142 First Aid Kit Acetylsalicylic Acid, Caffeine and 8 Mg Codeine Phosphate Entrophen Chewable Natural Aspirin plus Tart Cherry Dietary Supplement Vida Mia Pain Relief Adventure Medical Kits 1-4 Person First Aid Arthriten Inflammatory Pain Formula Ecotrin Regular Strength Family Wellness Effervescent Cold Relief Original Effervescent Pain Relief Fast Relief ARC FIRST AID Contains 101 PIECES Hardcase Alka-Seltzer Plus Day and Night Cold Asa Suppositories 650mg Enteric Coated Aspirin regular strength Geritrex Aspirin Low Strength Chewable Aspirin Lowprin 80mg Medi First Plus Pain Ache Asadol 325mg FormuCare Aspirin Entrophen Bio-asa Fasprin C2 Buffered Tab Pain Terminator DG Health migraine relief Aspirin 325 Mg EC Dr Pausins Low Dose Chewable Aspirin Cherry Flavor Adult Low strength Aspirin 4248 First Aid Kit Aspirin Plus Stomach Guard Extra Strength Acetaminophen, Aspirin, Caffeine Anacin Caplets Equate Effervescent Cold Relief Exaprin HyVee Health Effervescent Cold Relief Cardiospirina 81 mg Tabletas con cubierta enterica Pain Free Plus Anacin Effervescent Pain Relief Fast Relief Fast Relief Extra Strength Muscle & Back Pain Relief With Asa Aspirin 325mg Effervescent Pain Relief Excedrin PM Triple Action Caplets Family Care Effervescent Antacid and Pain Relief Robaxisal C-1/8 Tablets Alka Seltzer Evt Aspirin Enteric Coated Low Dose Excedrin Extra Strength Geltabs Alka-Seltzer Plus Cold Sparkling Original Equate Migraine Relief Amazon Basic Care Migraine Relief Rivasa 80 Mg EC Asa 80mg Tylo Migraine (Acetaminophen) 10 Person ANSI 4216 First Aid Kit Rivasa 81 Mg EC Topcare Migraine Formula A.C. & C. 8 mg Nezger Tab Buffered Aspirin Regular Strength Berkley and Jensen Migraine Relief EXTRA STRENGTH Headache Relief geltabs Asaphen Plus 325 Medi First Plus Aspirin Excedrin Menstrual Complete 282 Tablets Aspir-81 Equate Extra Strength Effervescent Antacid and Pain Relief Alka-Seltzer Plus Cold Formula (Orange Zest) Acetaminophen, Aspirin and Caffeine Calmine Tab Phenaphen No.2 Cap Equaline migraine formula Norgesic Forte Aspirin Backache Pain Aid Coraspirina 81 mg Tabletas con cubierta enterica 4227 First Aid Kit Aspirin Adult low dose Aspirin Low Dose Enteric Coated Extra Strength Muscle & Back Pain Asa 500 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 500 mg MEDIQUE Aspirin Rapid Comfort Aspirin Goodys Back and Body Pain Rite Aid Antacid and Pain Relief Aspergum Orange 325 mg Asatab EC 650mg Extra Pain Reliever Good Sense Aspirin Enteric Safety Coated Family Wellness Effervescent Cold Relief Orange Pronal C1/4 Capsules Asprin Aspirin 81 MG Extra Strenght Headache Relief Pronal Tablets Aspirin Enteric Aspirin Low Dose Chewable Orange Aspergum 325 Mg (cherry) Aspirin 81mg Adult Low Dose Coryphen 325 Codeine 30 Tab Extra Strength Midol Relief Berkley and Jensen Migraine Formula Ag-asa Chew Cove Migraine Relief Physicians Care Aspirin Rexall Coated Daily Low Dose Asa FIRST AID Contains 303 PIECES HARDCASE Aspirin Coated for Delayed Release Regular Strength Axisal-C1/8 Alka-Seltzer Plus Cold Sparkling Original PowerFast Fizz 4356 First Aid Kit Aspirin Plus Stomach Guard Tab Best Choice Pain Relief Powder PMS-pharnal-C1/2 Capsules Adult Chewable Aspirin Aspirin EC Low dose aspirin 81mg Robaxisal Tablets Uline Aspirin Health Mart Aspirin Asa Extra Strength Tab 500mg Pro-aas EC Asa Ect 650mg Coated Aspirin Low-dose 217 Strong Tab 81 mg Low Dose Aspirin Pravigard Pac Medi First Pain Ache 4139 First Aid Kit Phenaphen No.3 Cap Safety Coated Aspirin 325 mg Regular Strength Ac&c Tablets Neutra-seltzer Picot Plus Effervescent Value Pharma Aspirin Pain Reliever Physicians Care Extra Strength Pain Reliever Extra Strength Asa 500mg Rx Act Aspirin Alka Seltzer Pro-aas EC - 80 Aspirin 5 grain Value PharmaPain Reliever Extra Strength Bayer Migraine Formula Pain Stoppers EX Relief Asa Extra Strength Green Guard Extra Strength Pain Relief Low dose Chewable Aspirin 222 Tablets 4211 First Aid Kit BackAid Inflammatory Pain Formula Asa Tab 325mg ASPIRIN Low Dose Bufferin Extra -strength Aspirin Regular Strength Bubbles R Better Effervescent Cold Relief Extraprin Asa Acetylsalicylic Acid Vanquish Good Neighbor Pharmacy aspirin orange flavor chewable Equaline Effervescent Antacid and Pain Relief Fiorinal-C 1/2 Drug Mart Effervescent Pain Relief Fiorinal Tab Publix Super Markets Inc Xpect Pain Away Extra Strength Enteric coated aspirin Regular strength Alka-Seltzer Plus Severe Cold Powerfast Fizz Night Aspirin Low Strength, Enteric Cardiaspirin Protect Rexall Aspirin Walgreens Effervescent Cold Relief Plus ShopRite Migraine Formula Acetaminophen 250mg Aspirin 250mg Caffeine 65mg Health Mart Migraine Formula 4230 First Aid Kit Low Dose Chewable Aspirin 4246 First Aid Kit Enteric Coated Aspirin Regular Strength Asa-caffeine-codeine Health Mart Regular Strength Enteric Coated Aspirin Kroger Effervescent Cold Relief Nra-asa 80 Mg Croquable Alka-Seltzer Plus Severe Cold and Flu FIRST AID Contains 404 PIECES Aspirin 325 mg Care One headache relief added strength Aspirin Aspirin Chewable Low Dose Asatab EC 325mg Asa 325mg PHL-asa E.C. PMS-pharnal Tablets Rugby Adult Aspirin Pharbest Aspirin 325mg Alka Seltzer Original Ag-asa EC Aspir Low A.S.A. PMS-asa EC Aspirin Rapid Relief Dr Pausins Low Dose Chewable Aspirin Orange Flavor Ascriptin Regular Strength Buffered Aspirin Rapidol Aspirin Display 2x25 692 Tablet Alka-seltzer Flavoured Aramark Pain-Free Extra Strength Asa Daily Low Dose Good Sense Effervescent Cold Relief Asa-650 Comprimes Retard Medique at Home Aspirin Acetylsalicylic Acid, Caffeine & 8 Mg Codeine Phosphate Tablets Alka-Seltzer Original Flavor 4389 First Aid Kit Aspirin Extra Strength Asaphen E.C. 80 mg Back and Body Extra Strength Direct Safety Aspirin Trianal C? Safety Coated Aspirin 81 mg Low Dose Trianal Capsules Uricalm Intensive 4249 First Aid Kit Bufferin Alka Seltzer Plus Cold Sunmark aspirin adult low strength Darvon N Compound Pulvule 405 Sunmark Aspirin Adult Low Strength GOODYS Extra Strength Headache Mixed Fruit Blast A.C.& C Tablets Bayer Aspirin Aspirin Chewable Tablets 325mg Enteric Coated Asa 325 mg Medique Products Aspirin Aspirin 81mg Enteric coated Delayed Release Equagesic Rivasa Fc Headache Relief PM Extra Strength Headache Aspirin 81mg Quick Chews Bayer Headache Relief Added Strength Pain Stoppers Tri-Buffered Aspirin Taro-dipyridamole/ Asa Muscle Relaxant and Analgesic Seedalmerk 4251 First Aid Kit Acetaminophen Aspirin and Caffeine Alka-seltzer Original Equate Effervescent Antacid and Pain Relief Aspirin Extra Strength With Stomach Guard Pain Relief Aspirin Soma Low Dose Miniprin Enteric Safety Coated Assured Aspirin Pain Reliever Rivasa 80mg Croquable - Tab Dollar General Headache Powders Low Dose Aspirin Low Dose Migraine Formula Crane Safety Aspirin Aspirin Low Strength Adult Dolodol Genuine Bayer Aspirin GFA First Aid 75 Person Metal Case Medi-First Plus Aspirin MEDI-FIRST Tri Buffered Aspirin Pain Reliever Plus Signature Care Migraine Relief Sunmark Aspirin Berkley and Jensen Aspirin 4346 First Aid Kit 4365 First Aid Kit Alka-Seltzer Plus Severe Cold and Cough PowerFast Fizz Aspirin and Extended-release Dipyridamole Sunmark aspirin low dose Adult Low Dose Aspirin Euro Asa 325mg Chewable Tablet Up and Up aspirin Phenaphen No 3 Cap Bayer Advanced Aspirin Regular Strength Pronal Capsules Quality Choice Pain Relief Powder Aspirin to Go Quality Choice Extra Strength Effervescent Antacid and Pain Relief ASPIRIN 81 MG Low Dose Phenaphen No.4 Cap Care One Original Antacid and Pain Relief 4224 First Aid Kit Aspirin Chewable, Low Dose CVS Health Extra Strength Antacid and Pain Reliever Leader Effervescent Antacid and Pain Relief Acetylsalicylic Acid Tab 325mg BP Aspirin Safety coated Methoxisal-C 1/8 Chewable Aspirin Aspirin 81 mg Enteric Coated Pronal - C1/2 Capsules Lil Drug Store Aspirin 325 50 Person ANSI WinCo Foods Effervescent Cold Relief Coachs First Aid Contains 102 Pieces Market Basket Effervescent Antacid and Pain Relief 4134 First Aid Kit Equaline Aspirin Ready America First Aid Pocket - 33 Pieces Teva-tecnal C 1/2 Aspirin 325 Enteric Aspirin Tri-buffered Asa Tab GenCare Headache Relief Apo Asa Tab 325mg Nervine Tab Goodys Cool Orange C2 Tab With Codeine 692 Tab Pain Reliever Extra Strength Dr Pausins Low Dose Aspirin BC Arthritis Topcare Aspirin Adalat XL Plus Medi First Plus Pain Zapper Norgesic Percodan Aspirin 50 CT Low Dose Aspirin Enteric Safety Coated Aspirin Adult Low Strength Dg Health Migraine Relief Robaxisal Extra Strength Adult Low Strength Aspirin Coryphen 325 Tab Enteric Coated Asa Tablets 325mg Painex Tab 0.25gr Alka-seltzer Flavoured - Evt Good Neighbor Pharmacy Aspirin Easy Care First Aid Kit - Comprehensive Medi-First Aspirin Anacin AF 4215 First Aid Kit Nervine Dristan Capsules 7 Select Adult Chewable Aspirin Alka-Seltzer Plus Cold Day and Night Family Wellness Migraine Alka-Seltzer Plus Severe Cold PowerFast Fizz Orange Zest Aspirin Regular Strength Regular Strength Valumeds Aspirin Headache Relief to Go A.S.A. Tablets 5gr BP Alka-Seltzer Plus Night Cold Formula (Lemon) Meijer Effervescent Cold Relief Muscle & Back Pain Asa 325 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 325 mg Protection ARC FIRST AID Contains 303 PIECES ARC Emergency Preparedness FIRST AID Contains 202 PIECES Oxycodone and Aspirin Aspirin enteric coated low dose Sns-asa EC Up and Up Aspirin Acetylsalicylic Acid 325mg Tablets USP Coated Aspirin Butalbital, Aspirin, Caffeine and Codeine Phosphate Excedrin Migraine Geltabs Alka-Seltzer Lemon Lime ARC FIRST AID Emergency Preparedness Contains 167 PIECES Extra Strength Pain Relief Extra Strength Back and Body Family Wellness Migraine Relief Ecotrin Bufferin Low Dose Buffered Aspirin Madelon Acetylsalicylic Acid Extra Strength 500mg Tablets USP Yosprala Dg Health Headache Relief Added Strength Chewable Daily Low Dose Asa First Aid Direct Aspirin 4154 First Aid Kit Aggrenox 4395 First Aid Kit Asa, Caffeine & 8mg Codeine Phosphate Pro-aas - 80 (croquable) C2 Buffered With Codeine Tab 4221 First Aid Kit Tabcin 500 Alka-Seltzer Plus Cold Medicine Sparkling Original Smart Sense Effervescent Cold Relief Ac and C Tab 1/8gr EC-81Aspirin Enteric Coated ARC FIRST AID Contains 404 PIECES Endodan Orphenadrine Citrate Aspirin Caffeine GFA First Aid Kit Essentials - 33 Pieces Smart Sense Effervescent Antacid and Pain Relief Acetylsalicylic Acid Coated Alka-Seltzer Plus Multi-Symptom Cold Night Aspirin adult low strength Effervescent Cold Relief - Orange Excedrin Extra Strength and Excedrin Tension Headache Basic Dental Emergency Kit Adults Low Strength Aspirin Midol Regular Asa 975 Tab Goodys Thompson XS Pain Ache Aspirin - Children's Size 80mg Aspirin Chewable Tablets Regular strength aspirin Alka-Seltzer Extra Strength Dollar General Effervescent Cold Relief Aspirin and Dipyridamole Coricidin Nd Tab ALKA SELTZER PLUS Cold Day and Night Effervescent Acetaminophen Aspirin Caffeine Walgreens Effervescent Pain Relief Genuine Aspirin Caring Mill Migraine Relief Novo-propoxyn Compound Cap Methoxisal Aspirin Express Pack Duoplavin Flanax Aspirin Pain Reliever Fiorinal Effervescent Antacid and Pain Relief Jamp-asa 81mg EC Xpect Pain Away Topcare Headache Relief Aspirin Stomach Guard Regular Strength Sunmark Aspirin Regular Strength Coated Daily Low-dose Asa Adult Low Dose Asa-325 Comprimes Retard Enteric Coated Daily Low Dose Asa 81 mg Smart Sense Migraine Formula Pal-pravastatin-asa Aspirin Regimen Clopidogrel/acetylsalicylic Acid Zentiva Aspirin Enteric Coated, Regular Strength St. Joseph Safety Coated Aspirin ConRx pain Reliever Dg Health Aspirin 4250 First Aid Kit Enteric Coated Low Dose Aspirin Excedrin PM Triple Action Caplets and Excedrin Extra Strength Pain Reliever Aspirin 81 mg Low Dose Vanquish Digital Headache Medpurine Sunmark Migraine Relief 4342 First Aid Kit Acetylsalicylic Acid Tab 325mg Handy Solutions GENUINE ASPIRIN BAYER 4240 First Aid Kit Chewable Aspirin Low Dose Pain Free Pamprin Max Menstrual Pain Relief Aramark Aspirin Asaphen EC Bayer Aspirin Regimen enteric coated Adventure Medical Kits 1-2 Person First Aid Rapidol Aspirin Biovanta Trip Action Lemon and Honey 292 Tab Regular Strength Asa Chronic Pain/Fever Relief Excedrin Extra Strength HEB Extra Strength Effervescent Antacid and Pain Relief Oxycodone Hydrochloride and Aspirin Headache Formula Added Strength St. Joseph Low Dose Aspirin Aspirin Stomach Guard Extra Strength Best Choice Effervescent Cold Relief Herbopyrine Tab 325mg Butalbital, Aspirin, Caffeine, and Codeine Phosphate Aspirin Coated for Delayed Release Extra Strength Arco Pain Tab MEDI-FIRST Aspirin Norgesic Forte Tab Careone Aspirin WinCo Foods Effervescent Antacid and Pain Relief aspirin Regular strength M-asa 80 Mg Croquable Alka-Seltzer Plus Cold and Cough Smart Sense migraine relief ACME FIRST AID Contains 404 PIECES Top Value Effervescent Pain Relief Equaline headache formula added strength Asatab 80 Mg Chewable Tablets Sunmark Adult Aspirin Pain Stopper Extra Bayer Fast Release Bayer Headache Bayer Womens MICRO-COATED ASPIRIN 325 mg Good Neighbor Pharmacy Aspirin Enteric Safety Coated Leader Migraine Relief Chewable Adult Low Dose Aspirin 4032 First Aid Kit Enteric Coated A.S.A. MEDIQUE Tri Buffered Aspirin Kroger Effervescent Antacid and Pain Relief Anacin Extra Strength Tablet Anacin Tablet 4340 First Aid Kit Solves - aspirin Cherry Headache, Circle K BioElectro Day 4217 First Aid Kit Harris Teeter Migraine Relief Chewable Aspirin Adult low dose Headache Tab 300mg Excedrin Migraine, CVP HEALTH 4332 First Aid Kit Signature Care Aspirin Muscle Relaxant and Back Pain Relief Regular Strength Tablets DG Health Effervescent Antacid and Pain Relief Unishield Pain Ache Alka Seltzer Plus 2s Blister Pack Added Strength Pain Reliever Pain Stoppers Regular Extra Strength Headach Relief Carisoprodol and Aspirin Basic Care Aspirin Lo-asa 80mg Chewable - Tab Alka-Seltzer Original BUTALBITAL, ASPIRIN, CAFFEINE and CODEINE PHOSPHATE Robaxisal C 1/2 Safety Coated Low Dose Aspirin FIRST AID Contains 101 PIECES HARDCASE Extra Strength Midol Acetylsalicylic Acid A.S.A. Tablets 325mg Regular Strength Pain Relief Aramark Pain Free Biovanta Double Action PMS-asa Childrens Low Dose Aspirin Asa EC Enteric Coated A.S.a (caplet) CVS Health Antacid and Pain Reliever Good Sense Aspirin Lowprin 4196 First Aid Kit Enteric Coated Asa Tablets 650mg Sunmark migraine relief Alka-Seltzer Plus Severe Cold Night PowerFast Fizz A.S.A. Enteric Coated Tab 650mg Alka-Seltzer Plus Severe Cold PowerFast Fizz Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange Aspirin, Caffeine, and Dihydrocodeine Bitartrate Aspirin Tablets 325mg Bufferin Arthritis Critical Care Aspirin to Go Headache Pain Reliever Advanced Aspirin Adult Low Dose Enteric Coated Aspirin Muscle and Back Pain Relief Entrophen 325mg Tablets K-Mart SmartSense First Aid Contains 303 Pieces Enteric Coated Asa 650 mg Butalbital, aspirin, and caffeine Extra Strength Headache, Circle K Bc Max Aspirin-dipyridamole Apo-asa Ld FIRST AID Contains 303 PIECES Thrulife Extra Strength Headache Relief Handy Solutions Headache Pain Relief Headache Relief Walgreens Antacid Pain Relief Extra Strength Migralex Dr. Mauskop 25 Person ANSI Green Guard Pain and Ache Relief Safety Coated Aspirin Teva-tecnal C 1/4 BLUE ACME SLEEVE FIRST AID Contains 1000 PIECES Good Neighbor Pharmacy Migraine Relief Pain Stoppers Extra Alka-seltzer Morning Relief Muscle Relaxant and Back Pain Relief Extra Strength Tablets Muscle and Back Pain Relief With Asa Phenaphen No 4 Cap Aspirin - Children's Size - Tablets Aspirin Pain Relief Euro-asa EC Robaxisal C 1/4 Rx Act headache formula added strength Enteric Coated Aspirin Aspirin Enteric Safety Coated Bc Cherry Aspirin Safety Coated Adult Low Dose Unishield Aspirin 4313 First Aid Kit Extra Pain Relief Durlaza 365 Everyday Value Aspirin Coryphen 650 Tab Splizz Pain Reliever - Grapefruit-flavored Topcare Migraine Relief Medi First Plus Tri Buffered Aspirin Moore Medical Aspirin Asprin and Extended-release Dipyridamole Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces Percodan-demi Lab Safety Supply Aspirin Care One migraine relief Rivacodan BAYER Aspirin Extra Strength Caplets ULINE Aspirin Pain Terminator 2 Severe Muscle & Back Pain Relief Extra Strength Plus Pharma NSAID 325 mg Entrophen Ect 650mg Alka-Seltzer Plus Day Non Drowsy Cold Medicine Citrus Aspirin Pain reliver Asa Extra Strength Caplet 500mg Aspirin and Extended-Release Dipyridamole Novasen dihydrocodeine bitartrate and aspirin and caffeine DC Bufferin Regular Strength Pain Relief Aspirin chewable low dose 4229 First Aid Kit Pain Reliever Added Strength Top Value Effervescent Cold Relief - Orange Pain Relief Aspirin Chewable, Low Dose BAYER 500 mg Bayer PM Bayer Rapid Relief Right Remedies Aspirin Low Dose 81 mg 217 Enteric Coated A.S.a Low dose Aspirin Signature Care Effervescent Antacid and Pain Relief Advanced Pain Reliever Alka-Seltzer Plus Cold Formula (Cherry Burst) Anacin With Codeine Tab Pain Relief Maximum Strength Acido Acetilsalicilico With enteric coat Trianal C? 7 Select Migraine Formula Carisoprodol, Aspirin and Codeine Phosphate Entrophen Ect 975mg Up and Up Migraine Relief A.S.A. Enteric Coated Tab 325mg Regular Strength Tri-Buffered Aspirin Adult Low Dose Aspirin Enteric Coated Aspirin Low Dose Safety Coated Asa 500 Mg Tablets Extra Strength K-Mart SmartSense First Aid Contains 101 Pieces Asa Suppositories 150mg Aspirin Safety Coated Enteric, Regular Strength Extra Strength Aspirin Backache Uncoated Aspirin Anacin Extra Strength Caplets Ache and Pain Relief to Go Alka-Seltzer XTRA STRENGTH Alka-Seltzer Plus Cold and Cough Formula Dolex Forte Extra Strength Headache, Caseys 4good Bayer Plus Extra Strength Splizz Pain Reliever - Orange-flavored Meijer Effervescent Antacid and Pain Relief Super Extra Strength Aspirin Backache Walmart Pain Relief Powder Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored Extra Strength Pain Aid Exact Coated Daily Low-dose Asa Viva Asa 325 mg Asa 80 Bayer Low Dose PMS-pharnal-C 1/4 Capsules Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mg Clopidogrel/acetylsalicylic Acid Mylan Excedrin Migraine, TRAVEL BASIX Adult Low Dose Aspirin Enteric Safety Coated Asasantine Cap Healthy Accents headache relief added strength Alka-Seltzer Plus Multi-Symptom Cold and Cough Lowprin 325 Chewable Tablet Only For FIRST AID MEDICINE Aspirin and Dipyridamole Extended Release Regular Strength Enteric coated aspirin Aspirin With Stomach Guard Extra Strength - Tab Robaxisal Caplets Enteric coated aspirin Aspirin Enteric Coated Caplet 325mg 4304 First Aid Kit Entrophen 325mg Caplets A & C Tablets With Codeine 30mg ARC FIRST AID Contains 1000 PIECES Acetylsalicylic Acid Stomach Protection 325mg Tablets 4209 First Aid Kit Bayer Headache Relief ASPIRIN Regular Strength Equaline Effervescent Cold Relief Migraine Relief Astrin 5gr Excedrin Migraine Family Wellness Pain Relief Powder Orphengesic Forte 4213 First Aid Kit Trianal Tablet Enteric Coated Asprin Low Dose 4387 First Aid Kit ASPIRIN Low Strength Dye-Free Aspirin 81 Good Sense headache formula added strength First Aid Only Aspirin Asa Ect 325mg AspirinLow Dose Low Dose Aspirin Delayed Release Alka Seltzer Plus 1s Blister Pack 4291 First Aid Kit Good Sense Effervescent Antacid and Pain Relief Painex Tab 0.5gr Freds Effervescent Antacid Pain Relief Leader Headache Formula Added Strength Smart Sense Aspirin Low Dose Aspirin Enteric Safety-Coated Teva-oxycodan Methoxisal-C 1/2 TopCare Aspirin Jamp-asa Chew Butalbital, Aspirin, and Caffeine Healthy Accents migraine formula Regular Strength Aspirin EC Pain Reliever 2 Aspirin Enteric Coated Healthy Accents Aspirin C T Acetylsalicylic Acid Codeine and Caf Tab HyVee Health Effervescent Antacid and Pain Relief 4228 First Aid Kit Pain Aid ESF Antidol Tablets Adult Aspirin Regimen Low Dose Premier Value Antacid and Pain Relief Medicine Sunmark Headache Relief Childrens Aspirin Equagesic Tablets Aspirin Adult Low Dose Good Neighbor Pharmacy Headache Relief 282 Mep Tab A.S.A. 325 Mg Tablet Aspirin Low Dose Chewable Henry Schein Aspirin Fiorinal with Codeine Good Sense aspirin Extra Strength Pain Reliever Alka Seltzer Flavoured Ascomp with Codeine Auto 157 Bromo Seltzer Pharbest Regular Strength Aspirin Micro-Coated Aspirin Aspirin 81 Aspirin and Omeprazole Delayed-release Tab Ascriptin Maximum Strength Buffered Aspirin 4333 First Aid Kit Anacin ES ARC FIRST AID Contains 101 PIECES Lab Safety and Supply Tri Buffered Aspirin PHL-asa Family Wellness Aspirin Equate Daily Low-dose Methoxisal Extra Strength Dr. Juans Santo Remedio PARA LA ACIDEZ Natural Aspirin plus Lemon and Honey Dietary Supplement 4232 First Aid Kit Aspirin regular strength Headache Formula Extra Strength Publix Fast Relief Effervescent 4303 First Aid Kit Formu Care pain reliever added strength Health Mart Adult Aspirin Lowprin 325 Enteric Aspirin Regular Strength Alka-Seltzer Plus Excedrin PM Triple Action Caplets and Excedrin Tension Headache Aspirin Plus Stomach Guard Ext.stgth.caplet ShopRite Aspirin 4244 First Aid Kit Bayer Back and Body Extra Strength CVS Health Medication and Topical Refill Pouch Entrophen Ect 500mg Dolomine 37 EXCEDRIN MIGRAINE acetaminophen, aspirin (nsaid) and caffeine Aspirin Coated Caplets 325 mg Equate Aspirin Chewable First Aid Direct Chewable Aspirin ARC FIRST AID Contains 303 PIECES HARDCASE Muscle and Back Pain Relief With Asa Extra Strength North Aspirin Asaphen Quality Choice Effervescent Cold Relief - Orange Biovanta Trip Action Tart Cherry and Honey Zee-Seltzer Antacid and Pain Reliever Citramon Adventure Medical Kits 1-2 Person National Ski Patrol First Aid Equate Aspirin Alka-Seltzer Plus Multi-Symptom Cold Day and Night Medique Medi Seltzer Up and Up Chewable Aspirin Quality Choice Effervescent Cold Relief Plus Asa Ect 600mg Bi Electro Extra Strength CAREALL Aspirin Regular Strength Enteric Coated Aspirin GOOD NEIGHBOR PHARMACY FIRST AID Contains 202 PIECES Aspirin Arthritis Pain Relief 650 mg Novo Ac and C 8mg Tab enteric coated aspirin Regular Strength A.C. & C 8mg Tab Asa Aspirin Tab 325mg USP BioElectro Extra Strength Daytime Pain Relief Health Mart Migraine Relief Enteric Safety Coated Aspirin MooreBrand Aspirin Effervescent Orange Cold Relief Aspirin Safety Coated Excedrin Extra Strength Headache Entrophen 80mg Aspirin enteric safety coated Halfprin Low Dose Medi First Pain Relief Aspirin Adult Low Strength Aspirin Aspirin E-C Low Dose Safety Coated Butalbital, Aspirin and Caffeine Instantine - Tablets Conney Aspirin Only for Headache Ready America First Aid Outdoor- 107 Pieces Effervescent Cold Relief Jamp-asa EC Kirkland Signature Migraine Headache Relief Travel Savvy Aspirin Aspirin Low Dose Sugar Free Dr. Waynes Aspirin Low Dose Methoxisal-C 1/4 Alka-Seltzer Plus Cold Night Aspirin Chewable Crane Safety XS Pain Relief FIRST AID Contains 1000 PIECES Circle K Headache Relief Extra Strength Exaprin-AC Pain Relief PM Best Choice Effervescent Antacid Pain Relief A & C Tablets With Codeine 15mg 4305 First Aid Kit FIRST AID Contains 202 PIECES A.S.A. 80mg Acetylsalicylic Acid Tablets Adult Aspirin Regimen Alka-Seltzer Plus Cold Orange Zest Neo Tigol Tab Equaline aspirin adult low dose Aspirin Night-time Leader Aspirin Walgreens Pain Relief Powder Aspirin 81mg Enteric coated Low Strength Aspirin Regimen Aspirin Chewable Tablets - 325mg Bayer AM extra stength 4355 First Aid Kit Arthriten Max 292 Tablets Aspirin Granules Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Top Value Effervescent Cold Relief Dr Pausins Aspirin Topcare Headache Formula Rugby Aspirin Acetylsalicylic Acid 325mg Tab Foster and Thrive Migraine Relief Acetylsalicylic Acid Tab 300mg Aspirin 81mg Aspirin Migraine Signature Care Aspririn Stanback Circle K Aspirin 325 Deluxe Dental Emergency Kit Family Wellness Effervescent Antacid and Pain Relief Good Sense Migraine Formula Praxis Asa EC 81 Mg Daily Low Dose Excedrin Extra Strength Caplets Spasmhalt-asa-8 Smart Health Aspirin Regular Strength Alka-Seltzer Goodys Migraine Relief Asa 81 mg A.S.A. (acetylsalicylic Acid) Tab 325mg USP Alka Seltzer Originial 1s Blister Pack Asa EC 80 Asa Tab 325mg Enteric Coated Excedrin Extra Strength Pain Reliever Methocarbamol and Aspirin pain relief aspirin Low Dose Low Dose Aspirin 81 mg Safety Coated Basic Care Migraine Relief Tri-Buffered Aspirin Regular Strength Extra Strength Aspirin PMS-pharnal Capsules GENUINE FIRST AID Emergency Preparedness Contains 167 Pieces Health Sense Aspirin 81 Goodys Extra Strength London Drugs Coated Daily Low-dose Asa Aspirin Extra Strength 500mg Tab USP Aspirin Enteric Safety-Coated Aspica (Aspirin) 4388 First Aid Kit GOODYS Hangover Extra Strength Headache Relief NobleAid PAIN RELIEVER Orphenadrine Citrate, Aspirin and Caffeine Alka-Seltzer Hangover Relief Pain Relief Aspirin Low Dose Reese Headache Powders Vazalore C-2 Buffered With Codeine Headache relief Extra Strength McKesson Aspirin Pain Relief Extra Strength Kroger Value Aspirin Enteric Coated Asa Daily Low Dose Clopidogrel Kit Aspirin NSAID Low Dose Aspirin Phenaphen No 2 Cap 4376 First Aid Kit BC Cherry Dry Socket Paste Acetaminophen, Aspirin and Codeine Phosphate A.S.A. With Methocarbamol Night-time Extra Strength St. Joseph Chewable Low Dose Aspirin Unishield Pain Zapper Care One Aspirin Natural Aspirin plus Immune Supporting Dietary Supplement Fairfield Health Products Extra Strength MYGRIN Nighttime Aspirin With Stomach Guard Pain Relief Added Strength Asa 80 mg Asa and Caffeine Synalgos Acetylsalicylic Acid Extra Strength Stomach Protection 500mg Caplets Coated Daily Low Dose Asa 81 mg Excinol Migraine (Acetaminophen) Headache Relief Extra Strength Aspirin 81 mg Euro Asa Health Sense Ecpirin Buffered Aspirin Aspi-Cor Aspirin Adult low strength Medique Pain Off Regular Strength Aspirin
Indication	Pain, fever, and inflammation Acetylsalicylic acid (ASA), in the regular tablet form (immediate-release), is indicated to relieve pain, fever, and inflammation associated with many conditions, including the flu, the common cold, neck and back pain, dysmenorrhea, headache, tooth pain, sprains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, and various injuries. It is also used for symptomatic pain relief after surgical and dental procedures [FDA label]. The _extra strength_ formulation of acetylsalicylic acid is also indicated for the management migraine pain with photophobia (sensitivity to light) and phonophobia (sensitivity to sound)[FDA label]. Other indications ASA is also indicated for various other purposes, due to its ability to inhibit platelet aggregation. These include: Reducing the risk of cardiovascular death in suspected cases of myocardial infarction (MI) [FDA label]. Reducing the risk of a first non-fatal myocardial infarction in patients, and for reducing the risk of morbidity and mortality in cases of unstable angina and in those who have had a prior myocardial infarction [FDA label]. For reducing the risk of transient ischemic attacks (TIA) and to prevent atherothrombotic cerebral infarction (in conjunction with other treatments) [FDA label]. For the prevention of thromboembolism after hip replacement surgery [FDA label]. For decreasing platelet to platelet adhesion following carotid endarterectomy, aiding in the prevention of transient ischemic attacks (TIA) [FDA label]. Used for patients undergoing hemodialysis with a silicone rubber arteriovenous cannula inserted to prevent thrombosis at the insertion site [FDA Label]. Important note regarding use of the extended-release formulation [F4405] In the setting of acute myocardial infarction, or before percutaneous interventions, the extended-release form of acetylsalicylic acid should not be used. Use immediate-release formulations in scenarios requiring rapid onset of action [Label, F4405]. The extended-release form is taken to decrease the incidence of mortality and myocardial infarction (MI) for individuals diagnosed with chronic coronary artery disease (CAD), including patients with previous myocardial infarction (MI) or unstable angina or with chronic stable angina. Additionally, the extended-release form is used to decrease the risk of death and recurrent episodes of stroke in patients with a history of stroke or TIA [F4405].
Categories	Acids, Carbocyclic Agents causing angioedema Agents causing hyperkalemia Agents that produce hypertension Alimentary Tract and Metabolism Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) Antiinflammatory and Antirheumatic Products Antiplatelet agents Antipyretics Benzene Derivatives Blood and Blood Forming Organs Cardiovascular Agents Cyclooxygenase Inhibitors Cytochrome P-450 CYP2C19 Inducers Cytochrome P-450 CYP2C19 Inducers (strength unknown) Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Decreased Platelet Aggregation Decreased Prostaglandin Production Drugs that are Mainly Renally Excreted Hematologic Agents Hydroxybenzoates Musculo-Skeletal System Nephrotoxic agents Non COX-2 selective NSAIDS OAT1/SLC22A6 inhibitors OAT3/SLC22A8 Inhibitors P-glycoprotein inducers P-glycoprotein substrates Peripheral Nervous System Agents Platelet Aggregation Inhibitors Excl. Heparin Salicylates Salicylic Acid and Derivatives Sensory System Agents Stomatological Preparations UGT1A6 substrate
ATC-Code	B01AC06 C07FX04 C10BX04 M01BA03 C10BX02 N02BA71 B01AC56 N02AJ07 N02AJ02 N02BA01 B01AF51 C10BX05 N02BA51 A01AD05 C10BX01 C07FX03 N02AJ18 C10BX12 C10BX08 C10BX06 C07FX02
CAS number	50-78-2

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Prostaglandin G/H synthase 1	MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...	unknown	inhibitor
3-hydroxy-3-methylglutaryl-coenzyme A reductase	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYEC...	unknown	inhibitor
Prostaglandin G/H synthase 2	MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFY...	unknown	inhibitor
Aldo-keto reductase family 1 member C1	MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHID...	unknown	inhibitor
5'-AMP-activated protein kinase	MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTG...	unknown	activator
Endothelin-1 receptor	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVT...	unknown	inhibitor
Cellular tumor antigen p53	MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDI...	unknown	inducer
Endoplasmic reticulum chaperone BiP	MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRV...	unknown	inhibitor,binder
Ribosomal protein S6 kinase alpha-3	MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEI...	unknown	inhibitor
NF-kappa-B inhibitor alpha	MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQ...	unknown	inhibitor
Tumor necrosis factor-inducible gene 6 protein	MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYHREARSGKYKLT...	unknown	inhibitor,downregulator
Caspase-1	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATV...	unknown	inhibitor,downregulator
Caspase-3	MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIII...	unknown	inhibitor,downregulator
Inhibitor of nuclear factor kappa-B kinase subunit beta	MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQEL...	unknown
Extracellular signal-regulated kinase (ERK)	MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR...	unknown
G1/S-specific cyclin-D1	MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQK...	unknown	downregulator
Myc proto-oncogene protein	MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQ...	unknown	downregulator
Proliferating cell nuclear antigen	MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQL...	unknown	downregulator
Cyclin A	-	unknown	downregulator
Sialidase-1	MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAEND...	unknown	inhibitor
Cytochrome P450 2C19	MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDV...	unknown	inducer
Cytochrome P450 2C9	MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI...	unknown	substrate
UDP-glucuronosyltransferase 1-6	MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLS...	unknown	substrate
Arylamine N-acetyltransferase 2	MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMEL...	unknown	substrate
Solute carrier family 22 member 6	MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCR...	unknown	inhibitor
ATP-dependent translocase ABCB1	MDLEGDRNGGAKKKNFFKLNNKSEKDKKEKKPTVSVFSMFRYSNWLDKLY...	unknown	substrate,inducer,modulator
Organic anion transporter 3	MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCR...	unknown	inhibitor
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL25
PubChem	2244
ChEMBL	CHEMBL25
ChEBI	CHEBI:15365
CCDC/CSD	ACSALA21, ACSALA23, ACSALA14, TAZRAO01, DIFQAK, ACSALA20, DIPJAQ, VUGMIT, ACSALA26, ACSALA15, ARIFOX, KEWNOQ, ACSALA17, ACSALA25, ACSALA01, ACSALA19, SIBYUA, ACSALA27, TAZRAO, HUNJEH, ACSALA28, SIBYUA01, ACSALA02, ACSALA08, ACSALA07, ACSALA05, ACSALA03, ACSALA04, ACSALA06, ACSALA11, ACSALA09, SIBYUA02, ACSALA29, GARYEH, HAPCOU
COD	4100978, 1515581, 1515582, 1516479, 1516480, 1516481, 2104857, 7050897, 7050898, 7050899, 7050901, 7050900, 7050902, 7050903