AIN

2-(ACETYLOXY)BENZOIC ACID

Created:	2004-04-08
Last modified:	2020-05-26

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8 entries where AIN is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	21
Chiral Atom Count	0
Bond Count	21
Aromatic Bond Count	6

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Chemical Component Summary
Name	2-(ACETYLOXY)BENZOIC ACID
Synonyms	ACETYLSALICYLIC ACID; ASPIRIN
Systematic Name (OpenEye OEToolkits)	2-acetyloxybenzoic acid
Formula	C₉ H₈ O₄
Molecular Weight	180.157
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(Oc1ccccc1C(=O)O)C
SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
Canonical SMILES	CACTVS	3.341	CC(=O)Oc1ccccc1C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CC(=O)Oc1ccccc1C(=O)O
InChI	InChI	1.03	InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
InChIKey	InChI	1.03	BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00945 ?
Name	Acetylsalicylic acid
Groups	approved vet_approved
Description	Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
Synonyms	Acetylsalicylic acid o-carboxyphenyl acetate Aspirin ácido acetilsalicílico Lysine acetylsalicylate Acetylsalicylate Acide acétylsalicylique Acetylsalicyls?ure acide 2-(acétyloxy)benzo?que 2-Acetoxybenzenecarboxylic acid Salicylic acid acetate Polopiryna Acidum acetylsalicylicum ASA Aspirina O-acetylsalicylic acid 2-Acetoxybenzoic acid Azetylsalizyls?ure o-acetoxybenzoic acid
Brand Names	Rivasa 80 Mg EC Low Dose Miniprin Enteric Safety Coated Entrophen Ect 650mg Extra Strength Muscle & Back Pain Relief With Asa Quality Choice Effervescent Cold Relief Plus Nervine Bayer Headache Relief Safety Coated Low Dose Aspirin Zee Aspirin Asaphen Alka-Seltzer Plus Severe Cold and Flu Sunmark migraine relief Lowprin 325 Aspirin Extra Strength M-asa 80 Mg Croquable ConRx pain Reliever Lil Drug Store Headache Relief Extra Strength Excedrin PM Triple Action Caplets and Excedrin Extra Strength Pain Reliever A.S.A. Enteric Coated Tab 325mg Methoxisal 222 Tablets Aspirin Low Strength, Enteric Asa Tablets USP 325 mg Foster and Thrive Migraine Relief Conney Aspirin Medique Pain Off Endodan Alka-Seltzer Plus Cold Day and Night Publix Super Markets Inc Alka Seltzer Plus 1s Blister Pack 7 Select Adult Chewable Aspirin Anacin With Codeine Tab Acetaminophen Aspirin Caffeine Dr Pausins Low Dose Chewable Aspirin Cherry Flavor Equagesic Tablets GENUINE FIRST AID Emergency Preparedness Contains 167 PIECES HARDCASE Bayer Aspirin Adult Low Dose Novo Ac and C 8mg Tab Aspirin Low Dose Enteric Coated Equagesic Excedrin Extra Strength Caplets Bayer Back and Body Extra Strength Enteric Coated Asa Tablets 650mg Biovanta Trip Action Green Apple and Honey Equaline headache formula added strength Good Neighbor Pharmacy Headache Relief Aspirin Enteric Safety Coated HyVee Health Effervescent Antacid and Pain Relief Asa 80 mg MEDIQUE Aspirin 50 Person ANSI Extra Strength Aspirin Backache Extra Strength Headache, Circle K Geritrex Aspirin Aspergum Orange 325 mg Value Pharma Aspirin Pain Reliever Asa EC Smart Health Aspirin Regular Strength Walmart Pain Relief Powder Best Choice Effervescent Antacid Pain Relief Sunmark Aspirin Adult Low Strength Lab Safety Supply Aspirin 7 Select Migraine Formula Regular Strength Aspirin EC pain relief aspirin Low Dose Aspirin and Omeprazole Delayed-release Tab Pain Away Plus Halfprin Low Dose Aspirin NobleAid PAIN RELIEVER A.C.& C Tablets Alka Seltzer Evt Aspica (Aspirin) Aspirin 81 MG Adult Low Dose Aspirin Enteric Safety Coated Rapid Comfort Aspirin Excinol Migraine (Acetaminophen) Up and Up Antacid and Pain Relief Harris Teeter Migraine Relief Bayer Migraine Formula Aspirin - Children's Size - Tablets A.S.A. (acetylsalicylic Acid) Tab 325mg USP Aspirin - Children's Size 80mg 4303 First Aid Kit Pronal C1/4 Capsules 4304 First Aid Kit Headache, Circle K Aspirin 325 mg Aspirin Tablets 325mg Extra Strenght Headache Relief Aspirin Enteric Coated Praxis Asa EC 81 Mg Daily Low Dose Aramark Pain Free Chewable Low Dose Market Basket Effervescent Antacid and Pain Relief Alka-Seltzer Plus Cold and Cough EXTRA STRENGTH Headache Relief geltabs Alka-Seltzer Plus Multi-Symptom Cold Day and Night Extra Strength Aspirin Equaline Aspirin Walgreens Effervescent Cold Relief Plus Alka-Seltzer Plus Cold Sparkling Original Deluxe Dental Emergency Kit Rugby Aspirin Kirkland Signature Migraine Relief Natural Aspirin plus Tart Cherry Dietary Supplement Reese Headache Powders Tylo Migraine (Acetaminophen) Adult Chewable Aspirin Bc Cherry Arthriten Max Asa 500 Mg Tablets Extra Strength Bayer Genuine Aspirin C2 Buffered Tab Enteric Coated Low Dose Aspirin Headache Relief Extra Strength Critical Care Aspirin to Go Sunmark Migraine Relief Neutra-seltzer Alka-Seltzer Plus Cold Night Aspirin Enteric Coated Low Dose Calmine Tab Asaphen Plus 325 Low Dose Aspirin Chewable Acetylsalicylic Acid, Caffeine and 8 Mg Codeine Phosphate Enteric Coated Asa 325 mg Midol Regular Headache Formula Extra Strength Low dose aspirin 81mg Methoxisal Extra Strength Topcare Aspirin Coryphen 325 Codeine 30 Tab Ascriptin Regular Strength Buffered Aspirin HyVee Health Effervescent Cold Relief Health Mart Adult Aspirin Family Wellness Pain Relief Powder Pro-aas EC Crane Safety XS Pain Relief Nervine Tab Butalbital Compound Leader Effervescent Antacid and Pain Relief Circle K Headache Relief Extra Strength Tabcin 500 Equaline Effervescent Antacid and Pain Relief Aspirin Chewable Effervescent Pain Relief Fast Relief Fast Relief Dolomine 37 Asa Extra Strength Tab 500mg Signature Care Migraine Relief Asa Ect 600mg Sunmark Headache Relief Asa 81 mg Phenaphen No.4 Cap Rexall Aspirin BC Cherry FIRST AID Contains 101 PIECES Muscle & Back Pain Asa 325 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 325 mg 217 282 Tab BLUE ACME SLEEVE FIRST AID Contains 1000 PIECES Norgesic Aspirin 81 K-Mart SmartSense First Aid Contains 303 Pieces Jamp-asa Chew Health Mart Migraine Formula Best Choice Effervescent Cold Relief Lowprin 325 Chewable Tablet A.S.A. Enteric Coated Tab 650mg 4215 First Aid Kit Aspirin 5 grain First Aid Direct Aspirin Alka-Seltzer Plus Cold Sparkling Original PowerFast Fizz BUTALBITAL, ASPIRIN, CAFFEINE and CODEINE PHOSPHATE Medi-First Aspirin Basic Care Aspirin FIRST AID Contains 404 PIECES Alka-seltzer Original Up and Up aspirin Alka-Seltzer Plus Cold Orange Zest Apo-asa Ld Extraprin Green Guard Extra Strength Pain Relief Entrophen 80mg Pain Aid ESF Sound Body Migraine Relief Alka-Seltzer Original Flavor 292 Tablets Alka-Seltzer Plus Multi-Symptom Cold and Cough TopCare Aspirin Dr Pausins Aspirin Aspirin Migraine Tri-Buffered Aspirin BioElectro Extra Strength Daytime Pain Relief Kroger Value Aspirin A & C Tablets With Codeine 30mg Top Value Effervescent Pain Relief 4248 First Aid Kit 4332 First Aid Kit Butalbital, Aspirin and Caffeine Equate Daily Low-dose Aspirin Stomach Guard Regular Strength Leader migraine formula PHL-asa E.C. 4230 First Aid Kit Effervescent Cold Relief - Orange Alka Seltzer Plus 2s Blister Pack Medique Medi Seltzer 217 Strong Tab Muscle and Back Pain Relief Extra Strength Rivasa 80mg Croquable - Tab Excedrin Extra Strength Headache Regular Strength Pain Relief Pain Stoppers Extra Robaxisal Caplets Berkley and Jensen Migraine Formula ShopRite Migraine Formula Up and Up Aspirin Fiorinal with Codeine Dg Health Aspirin Bayer AM extra stength ARC FIRST AID Contains 101 PIECES Hardcase Equaline aspirin adult low dose Sns-asa EC Chronic Pain/Fever Relief Ache and Pain Relief to Go Dg Health Migraine Relief Excedrin Migraine Geltabs Henry Schein Aspirin Phenaphen No 3 Cap Robaxisal C 1/2 Excedrin Extra Strength Geltabs St. Joseph Safety Coated Aspirin Uricalm Intensive Aspirin With Stomach Guard Extra Strength - Tab Alka-Seltzer Plus Severe Cold PowerFast Fizz Day and Night Good Sense Aspirin Basic Care Headache Relief Extra Strength Back and Body Clopidogrel/acetylsalicylic Acid Mylan Pain Relief Maximum Strength Vanquish Digital Headache FormuCare Aspirin Orphengesic Forte Bayer Aspirin Regimen enteric coated Aspirin Enteric Safety-Coated A.S.A. 80mg Acetylsalicylic Acid Tablets Alka-Seltzer Plus Cold Medicine Sparkling Original Excedrin Extra Strength Micro-Coated Aspirin Protection Asprin Tri-Buffered Aspirin Regular Strength Painex Tab 0.25gr Robaxisal C-1/8 Tablets Aspirin Regular Strength Regular Strength Regular Strength Enteric coated aspirin Biovanta Trip Action Tart Cherry and Honey Orphenadrine Citrate Aspirin Caffeine Aspirin 81mg Goodys Migraine Relief Synalgos Pain Stoppers Sunmark Adult Aspirin Aspirin Safety Coated Acetaminophen 250mg Aspirin 250mg Caffeine 65mg Enteric coated aspirin Regular strength Leader Headache Formula Added Strength Asa-325 Comprimes Retard Adalat XL Plus Extra Strength Pain Aid Adult Aspirin Regimen Low Dose 4032 First Aid Kit Adventure Medical Kits 1-2 Person National Ski Patrol First Aid GFA First Aid 75 Person Metal Case 4142 First Aid Kit Antidol Tablets Apo Asa Tab 325mg Circle K Aspirin 325 Handy Solutions GENUINE ASPIRIN BAYER Caring Mill Migraine Relief Euro Asa Enteric Safety Coated Aspirin Aspirin, Caffeine, and Dihydrocodeine Bitartrate Alka-Seltzer Plus Cold and Cough Formula Topcare Migraine Formula BAYER 500 mg Alka-Seltzer Plus Cold Formula (Orange Zest) Pro-aas EC - 80 Asa Extra Strength Caplet 500mg Spasmhalt-asa-8 CVS All Purpose First Aid Kit Aspirin Thin coated Ecotrin Regular Strength Butalbital, Aspirin, Caffeine and Codeine Phosphate Chewable Adult Low Dose Aspirin Duoplavin Acetylsalicylic Acid 325mg Tab ARC FIRST AID Contains 1000 PIECES Extra Strength Headache Good Sense aspirin Thrulife Extra Strength Headache Relief Aspirin Low Dose Safety Coated Goodys Tri-buffered Asa Tab Adult Aspirin Regimen 4346 First Aid Kit Alka-Seltzer 4333 First Aid Kit Muscle Relaxant and Analgesic Natural Aspirin plus Immune Supporting Dietary Supplement Aspirin to Go Asa Acetylsalicylic Acid Dg Health Headache Relief 81 mg Low Dose Aspirin Ag-asa Chew Asa, Caffeine & 8mg Codeine Phosphate Health Sense Aspirin 81 Muscle and Back Pain Relief With Asa Picot Plus Effervescent Rexall Coated Daily Low Dose Asa Muscle Relaxant and Back Pain Relief Regular Strength Tablets Pain Stopper Extra Pain Aid Aspirin Express Pack Orphenadrine Citrate, Aspirin and Caffeine Phenaphen No.2 Cap DG Health migraine relief Blowfish Family Wellness Effervescent Cold Relief Original Leader Migraine Relief Leader Aspirin Aspirin With Stomach Guard Excedrin Extra Strength and Excedrin Tension Headache Quality Choice Effervescent Cold Relief - Orange Vazalore 4217 First Aid Kit Darvon N Compound Pulvule 405 Careone Aspirin Relief Asa Extra Strength Aspirin Enteric Coated, Regular Strength Basic Dental Emergency Kit Safety Coated Aspirin 325 mg Regular Strength C2 Buffered With Codeine Tab Pain Reliever 2 A & C Tablets With Codeine 15mg HEALTH SENSE Adult Chewable Low Strength Aspirin Alka Seltzer Lowprin 80mg Cardiospirina 81 mg Tabletas con cubierta enterica Astrin 5gr 4211 First Aid Kit GOOD NEIGHBOR PHARMACY FIRST AID Contains 202 PIECES Adventure Medical Kits 1-2 Person First Aid Effervescent Cold Relief Bio-asa Extra Strength Pain Reliever Neo Tigol Tab Pain Relief PM Sunmark aspirin adult low strength Good Sense Effervescent Cold Relief Exaprin-AC Acetylsalicylic Acid Tab 325mg BP Miniprin Bc Max Phenaphen No 4 Cap 4395 First Aid Kit Fiorinal-C 1/2 Zee-Seltzer Antacid and Pain Reliever Physicians Care Extra Strength Pain Reliever Advanced Aspirin Robaxisal Extra Strength Ana-dent Plus Pharma NSAID 325 mg Auto 157 Dollar General Headache Powders 4387 First Aid Kit Aspirin 81 mg Low Dose Coated Daily Low Dose Asa 81 mg Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mg Aspirin Extra Strength Plus Low Dose Aspirin Enteric Safety Coated Bayer Womens Pamprin Max Menstrual Pain Relief Clopidogrel/acetylsalicylic Acid Zentiva ASPIRIN Low Dose Bayer Advanced Aspirin Extra Strength aspirin Regular strength Good Sense Headache Relief Rivasa Fc 4227 First Aid Kit Headache Tab 300mg Extra Strength Asa 500mg North Aspirin Teva-tecnal C 1/2 Easy Care First Aid Kit - Comprehensive A.S.A. 325 Mg Tablet A.S.A. Tablets 5gr BP Low dose Aspirin Aspirin Plus Stomach Guard Extra Strength Regular Strength Enteric Coated Aspirin Pravigard Pac Aspirin Extra Strength With Stomach Guard Crane Safety Aspirin Aspirin EC EXCEDRIN MIGRAINE acetaminophen, aspirin (nsaid) and caffeine Aspirin Regular Strength Enteric Coated Asa Tablets 325mg Exact Coated Daily Low-dose Asa Excedrin PM Triple Action Caplets Pain Stoppers EX Super Extra Strength Aspirin Backache Family Wellness Migraine Relief Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces Effervescent Antacid and Pain Relief Good Sense Effervescent Antacid and Pain Relief GENUINE FIRST AID Emergency Preparedness Contains 167 Pieces Ac and C Tab 1/8gr PMS-pharnal-C1/2 Capsules Bayer Low Dose Medi First Plus Pain Ache 4244 First Aid Kit Bufferin Extra -strength Asasantine Cap Enteric Coated Aspirin Regular Strength Only for Headache Extra Pain Relief Flanax Aspirin Pain Reliever Acetylsalicylic Acid Coated Medique at Home Aspirin Oxycodone and Aspirin Bayer Good Neighbor Pharmacy Migraine Relief CAREALL Aspirin FIRST AID Contains 202 PIECES Aspirin 4214 First Aid Kit Asa Enteric Coated Daily Low Dose Asa 81 mg FIRST AID Contains 101 PIECES HARDCASE Aggrenox Thompson XS Pain Ache Aspirin Chewable Tablets 325mg Excedrin Migraine Pain Reliever Added Strength Aspirin-dipyridamole Splizz Pain Reliever - Grapefruit-flavored Coricidin D Tab Publix Fast Relief Effervescent Coricidin Nd Tab 25 Person ANSI Headache Relief PMS-pharnal-C 1/4 Capsules Aspirin Night-time Aspirin Safety Coated Enteric, Regular Strength Coryphen 650 Codeine 30 Tab Jamp-asa 81mg EC Migralex Dr. Mauskop Medi First Pain Ache Alka-Seltzer Plus 282 Mep Tab Xpect Pain Away Asa Tab 325mg Aspirin Pain reliver Pain Free Plus Anacin Extra Strength Anacin Asa and Caffeine Rx Act Aspirin Headache relief Extra Strength Migraine Formula Unishield Pain Zapper Alka-Seltzer Plus Severe Cold and Cough PowerFast Fizz ShopRite Aspirin 4376 First Aid Kit Aspirin Chewable Low Dose Smart Sense Migraine Formula 10 Person ANSI 292 Tab 4249 First Aid Kit Acetylsalicylic Acid Stomach Protection 325mg Tablets Acido Acetilsalicilico With enteric coat Bayer Headache Acetylsalicylic Acid A.S.A. Tablets 325mg Leader Low Dose Aspirin Enteric Coated A.S.a (caplet) Euro Asa 325mg Chewable Tablet A.S.A. Extra Strength Midol Relief MICRO-COATED ASPIRIN 325 mg 4229 First Aid Kit Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored Good Neighbor Pharmacy aspirin orange flavor chewable ACME FIRST AID Contains 404 PIECES Quality Choice Extra Strength Effervescent Antacid and Pain Relief Vida Mia Pain Relief Travel Savvy Aspirin Coryphen 325 Tab Methoxisal-C 1/8 Bayer Plus Extra Strength Excedrin Menstrual Complete MooreBrand Aspirin Plus Pharma NSAID Aspirin CVS Health Extra Strength Antacid and Pain Reliever Aspirin Adult low dose Clopidogrel Kit Effervescent Orange Cold Relief enteric coated aspirin Regular Strength Extra Strength Midol Carisoprodol, Aspirin and Codeine Phosphate Ascriptin Maximum Strength Buffered Aspirin Alka-Seltzer Plus Multi-Symptom Cold Night Xpect Pain Away Extra Strength Lab Safety and Supply Tri Buffered Aspirin Solves - aspirin Cherry MEDIQUE Tri Buffered Aspirin Acetylsalicylic Acid Extra Strength Stomach Protection 500mg Caplets Top Value Effervescent Cold Relief Aspirin Coated for Delayed Release Extra Strength Cardiaspirin Protect Kroger Effervescent Antacid and Pain Relief ARC FIRST AID Contains 101 PIECES Headache Relief Added Strength Regular Strength Aspirin A.S.A. With Methocarbamol Night-time Extra Strength Pharbest Regular Strength Aspirin PHL-asa Aspirin Chewable Tablets - 325mg Enteric Coated Aspirin regular strength Entrophen Ect 500mg Aspi-Cor Rx Act headache formula added strength London Drugs Coated Daily Low-dose Asa Healthy Accents headache relief added strength FIRST AID Contains 303 PIECES HARDCASE Aspirin 325 Mg EC Aspir Low Butalbital, Aspirin, Caffeine, and Codeine Phosphate Aspirin 325 Coraspirina 81 mg Tabletas con cubierta enterica AspirinLow Dose Low Dose Berkley and Jensen Aspirin A.C. & C. 8mg Coated Daily Low-dose Asa Zee Pain Aid Adult Low Strength Aspirin Equaline migraine formula Methoxisal-C 1/4 PMS-asa EC Alka-Seltzer Plus Day and Night Cold Topcare Headache Formula Aspir-81 Aspirin regular strength Coated Aspirin - Ect 80mg Family Care Effervescent Antacid and Pain Relief Low Dose Aspirin Enteric Safety-Coated 4232 First Aid Kit Pronal - C1/2 Capsules Enteric Coated Aspirin FIRST AID Contains 1000 PIECES Good Sense headache formula added strength Regular Strength Asa Arthriten Inflammatory Pain Formula Robaxisal Tablets Teva-tecnal C 1/4 Trianal C? 4305 First Aid Kit BAYER Aspirin Extra Strength Caplets Carisoprodol and Aspirin Low dose Chewable Aspirin Bi Electro Extra Strength Aspirin chewable low dose Aspirin Stomach Guard Extra Strength Alka-Seltzer Hangover Relief Moore Medical Aspirin Aspirin and Extended-release Dipyridamole Equate Migraine Relief Percodan Physicians Care Aspirin Care One migraine relief ASPIRIN 81 MG Low Dose HEB Extra Strength Effervescent Antacid and Pain Relief Citramon Pronal Tablets Instantine - Tablets Fiorinal Tab Leader Extra Strength Effervescent Antacid and Pain Reliever PhysiciansCare Extra Stregth Pain Reliever SohMed Pain Reliever Aspirin Chewable Tablets ARC FIRST AID Emergency Preparedness Contains 167 PIECES Best Choice Pain Relief Powder Rapidol Aspirin Arco Pain Tab 4154 First Aid Kit Aspirin NSAID Premier Value Antacid and Pain Relief Medicine Alka-Seltzer Plus Severe Cold Powerfast Fizz Night Lo-asa 80mg Chewable - Tab Methocarbamol and Aspirin Dye-Free Aspirin 81 4228 First Aid Kit Alka-Seltzer Plus Severe Cold PowerFast Fizz Non Drowsy St. Joseph Low Dose Aspirin 4291 First Aid Kit Smart Sense Chewable Aspirin Bufferin Low Dose Buffered Aspirin Extra Strength Headache, Caseys 4good Alka-seltzer Morning Relief Halfprin Low Dose Anacin Extra Strength Tablet Asa 325mg Bc Chewable Aspirin Oxycodone Hydrochloride and Aspirin ARC FIRST AID Contains 404 PIECES Artrifin 24 Caplets Aspirin Extra Strength 500mg Tab USP 4251 First Aid Kit Alka-Seltzer Lemon Lime Medi-First Plus Aspirin 4340 First Aid Kit Topcare Migraine Relief First Aid Direct Chewable Aspirin Asa Suppositories 150mg Trianal C? WinCo Foods Effervescent Cold Relief Family Wellness Aspirin Signature Care Aspirin Trianal Capsules Walgreens Effervescent Pain Relief Aspirin adult low strength Low Dose Aspirin Alka-seltzer Flavoured ARC FIRST AID Contains 303 PIECES Extra Strength Headach Relief Kirkland Signature Migraine Headache Relief 4225 First Aid Kit Asaphen E.C. 80 mg Fiorinal Pain Relief Aspirin Chewable, Low Dose PMS-pharnal Capsules Aspirin Low Strength Adult Ready America First Aid Outdoor- 107 Pieces PMS-asa Extra Strength Pain Relief Aspirin Enteric Acetaminophen, Aspirin and Caffeine Added Strength Pain Reliever Anacin Extra Strength Caplets Alka-Seltzer Plus Night Cold Formula (Lemon) Asa-caffeine-codeine Headache Formula Added Strength McKesson Aspirin Uncoated Aspirin Dry Socket Paste Good Neighbor Pharmacy Aspirin Smart Sense Effervescent Cold Relief Biovanta Double Action Coachs First Aid Contains 102 Pieces Care One Original Antacid and Pain Relief C2 Tab With Codeine Excedrin Migraine, CVP HEALTH Low Dose Aspirin Low Dose MEDI-FIRST Aspirin Pain Relief Aspirin Alka Seltzer Originial 1s Blister Pack Caring Mill Aspirin Aspirin Coated Caplets 325 mg Ecotrin Bayer Advanced Aspirin Regular Strength Aspirin Pain Relief Chewable Daily Low Dose Asa Madelon Aspirin Low Dose Chewable Orange Healthy Accents Aspirin Nra-asa 80 Mg Croquable Asa Suppositories 650mg Migraine Relief Only For FIRST AID MEDICINE Topcare Headache Relief Trianal Tablet Norgesic Tab Pain Relief Fast Relief Alka-Seltzer Plus Severe Cold PowerFast Fizz Freds Effervescent Antacid Pain Relief Quality Choice Effervescent Antacid and Pain Relief Mountain Series Weekender Medical 4196 First Aid Kit Equate Effervescent Antacid and Pain Relief Aramark Aspirin MYGRIN Nighttime Viva Asa 325 mg Rugby Adult Aspirin Effervescent Pain Relief Value PharmaPain Reliever Extra Strength Adult Low Dose Aspirin Medpurine Aspirin Tab 325mg USP Acetylsalicylic Acid Tab 325mg 4250 First Aid Kit Buffered Aspirin Euro-asa EC Hydrocodone Bitartrate and Aspirin Pain Terminator Acetylsalicylic Acid, Caffeine & 8 Mg Codeine Phosphate Tablets Acetylsalicylic Acid Extra Strength 500mg Tablets USP Entrophen 325mg Tablets Pain Relief Aspirin Low Dose Equate Effervescent Cold Relief GenCare Headache Relief St. Joseph Chewable Low Dose Aspirin Pronal Capsules Aspirin Safety coated 7 Select Aspirin BackAid Inflammatory Pain Formula GFA First Aid Kit Essentials - 33 Pieces Adult Low Dose Enteric Coated Aspirin Dollar General Effervescent Cold Relief 4365 First Aid Kit CVS Health Medication and Topical Refill Pouch Equate Aspirin Chewable Seedalmerk Smart Sense Aspirin Soma Axisal-C1/8 Walgreens Antacid Pain Relief Extra Strength Alka-Seltzer Plus Day Non Drowsy Cold Medicine Citrus Dr Pausins Low Dose Aspirin Entrophen Goodys Cool Orange Headache Muscle and Back Pain Relief With Asa Extra Strength Healthy Accents migraine formula Bufferin Regular Strength Pain Relief Enteric Coated Asa 650 mg A.C. & C. 8 mg Family Wellness Effervescent Antacid and Pain Relief Walgreens Pain Relief Powder Ac&c Tablets Aspirin Safety Coated Adult Low Dose Medi First Plus Aspirin Asa 325 Mg Tablets Regular Strength Quality Choice Pain Relief Powder Alka Seltzer Flavoured Durlaza Aspirin Delayed Release Bubbles R Better Effervescent Cold Relief Equate Aspirin 4213 First Aid Kit Rite Aid Antacid and Pain Relief Muscle Relaxant and Back Pain Relief Extra Strength Tablets Regular Strength Tri-Buffered Aspirin Signature Care Effervescent Antacid and Pain Relief Aspirin 81 mg Adult Low Dose Aspirin Enteric Coated Butalbital, Aspirin, and Caffeine Valumeds Aspirin Asa Chewable Tablets Bufferin 282 Tablets Health Mart Aspirin 4209 First Aid Kit Acetylsalicylic Acid 325mg Tablets USP ARC FIRST AID Contains 303 PIECES HARDCASE Entrophen 325mg Caplets Amazon Basic Care Migraine Relief Asa Ect 650mg Aspirin Plus Stomach Guard Tab Phenaphen No.3 Cap GOODYS Hangover Coryphen 650 Tab 692 Tablet Aspirin Regimen Asatab 80 Mg Chewable Tablets Butalbital, aspirin, and caffeine Phenaphen No 2 Cap 4313 First Aid Kit Ascomp with Codeine Family Wellness Migraine Aspirin E-C Low Dose Safety Coated GOODYS Extra Strength Headache Mixed Fruit Blast Asa Tab 325mg Enteric Coated Jamp-asa EC Headache Pain Reliever Pal-pravastatin-asa Acetylsalicylic Acid Tab 300mg 4221 First Aid Kit Aspirin Chewable, Low Dose Direct Safety Aspirin Extra Pain Reliever Ru-21 Hangover Relief Aspirin Low Dose Chewable ENTERIC COATED ASPIRIN Regular Strength Alka-Seltzer Extra Strength Alka-seltzer Flavoured - Evt Aramark Pain-Free Extra Strength Asprin and Extended-release Dipyridamole Aspirin Low Dose Sugar Free Buffered Aspirin Regular Strength Coated Aspirin Low-dose Pro-aas - 80 (croquable) Acetaminophen Aspirin and Caffeine Extra Strength Headache Relief Aspirin Rapid Relief Ready America First Aid Pocket - 33 Pieces St. Joseph Chewable Aspirin Chewable Aspirin Adult low dose Drug Mart Effervescent Pain Relief Pain Relief Added Strength Bayer Fast Release Care One Aspirin Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange Stanback Asa EC 80 Goodys Extra Strength Genuine Aspirin Meijer Effervescent Cold Relief FIRST AID Contains 303 PIECES Aspirin 81mg Quick Chews Muscle & Back Pain Relief Extra Strength Sunmark aspirin low dose Pain Relief Extra Strength Cove Migraine Relief Entrophen 650mg Caplet Ect Asadol 325mg Asatab EC 650mg Enteric coated aspirin Safety Coated Aspirin Acetaminophen, Aspirin and Codeine Phosphate Aspirin Adult Low Strength Exaprin Anacin ES Aspirin 81mg Enteric coated Low Strength Aspirin Regimen 4388 First Aid Kit Dristan Capsules Novo-propoxyn Compound Cap Low Dose Chewable Aspirin Health Sense Ecpirin Aspirin Granules Lowprin Circle K Headache Relief Chewable Low Dose Aspirin Excedrin Back and Body Adults Low Strength Aspirin Low Dose Aspirin 81 mg Safety Coated Good Sense Aspirin Enteric Safety Coated Alka-Seltzer Original ULINE Aspirin Aspirin 50 CT Enteric Coated A.S.a Headache Relief to Go Meijer Effervescent Antacid and Pain Relief Fiorinal-C 1/4 Green Guard Tri Buffered Aspirin relief Coated Aspirin EC-81Aspirin Enteric Coated Effervescent Pain Relief Fast Relief Formu Care pain reliever added strength Goodys PM Pain Reliever Pain Reliever Extra Strength Pain Stoppers Regular Robaxisal C 1/4 Asa-650 Comprimes Retard Extra Strength Muscle & Back Pain Asa 500 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 500 mg Teva-tecnal Alka-Seltzer Plus Night Cold Medicine Genuine First Aid Industrial First Aid 4240 First Aid Kit Anacin AF Pain Reliever CVS Health Antacid and Pain Reliever Aspirin Arthritis Pain Relief 650 mg Rivacodan Ag-asa EC Biovanta Trip Action Lemon and Honey Fasprin Health Mart Migraine Relief Lil Drug Store Aspirin 325 Norgesic Forte Asatab EC 325mg Chewable Aspirin Low Dose Pain Free Rapidol Aspirin Display 2x25 A.C. & C 8mg Tab Pain Terminator 2 Severe Alka Seltzer Original Aspirin enteric coated low dose Novasen Sunmark Aspirin Excedrin Extra Strength Pain Reliever Excedrin PM Triple Action Caplets and Excedrin Tension Headache Instantine Tab Aspirin 81mg Adult Low Dose Aspirin 81 mg Enteric Coated Aspirin and Extended-Release Dipyridamole Good Neighbor Pharmacy Aspirin Enteric Safety Coated Leader Cardinal Health Aspirin Percodan-demi Rivasa 81 Mg EC Safety Coated Aspirin 81 mg Low Dose 4134 First Aid Kit Childrens Aspirin Medi First Plus Pain Zapper Enteric Coated Asa Daily Low Dose Dr Pausins Low Dose Chewable Aspirin Orange Flavor Advanced Pain Reliever Aspirin Adult low strength Muscle and Back Pain Relief Pharbest Aspirin 325mg BC Arthritis Aspirin Coated for Delayed Release Regular Strength Asa 80 Asa 80mg Pain Reliever Plus First Aid Only Aspirin Anacin Tablet Equate Extra Strength Effervescent Antacid and Pain Relief Headache Relief PM Sunmark Aspirin Regular Strength Top Value Effervescent Cold Relief - Orange Green Guard Pain and Ache Relief Herbopyrine Tab 325mg Dr. Waynes Aspirin Low Dose Bayer Rapid Relief Asa Ect 325mg 4342 First Aid Kit Aspirin and Dipyridamole Extended Release Aspirin Low Dose Dg Health Headache Relief Added Strength Genuine Bayer Aspirin Yosprala Natural Aspirin plus Lemon and Honey Dietary Supplement Alka-Seltzer Plus Cold Formula (Cherry Burst) Family Wellness Effervescent Cold Relief Orange Enteric Aspirin Regular Strength Alka-Seltzer Plus Severe Cold PowerFast Fizz Orange Zest Coricidin Tab Handy Solutions Headache Pain Relief Equaline Effervescent Cold Relief Signature Care Aspririn Aspirin Coated Caplets 500mg Regular strength aspirin Aspirin enteric safety coated ALKA SELTZER PLUS Cold Day and Night Effervescent ASPIRIN Low Strength Fairfield Health Products Extra Strength C T Acetylsalicylic Acid Codeine and Caf Tab Health Mart Regular Strength Enteric Coated Aspirin C-2 Buffered With Codeine Enteric Coated Asprin Low Dose ASPIRIN Regular Strength Smart Sense migraine relief Excedrin Migraine, TRAVEL BASIX Medi First Pain Relief Bufferin Arthritis Teva-oxycodan Aspirin Enteric Coated Caplet 325mg K-Mart SmartSense First Aid Contains 101 Pieces 4355 First Aid Kit Asa 975 Tab Assured Aspirin Norgesic Forte Tab Enteric Aspirin Aspirin Adult Low Strength Aspirin Goodys Cool Orange Kroger Effervescent Cold Relief 4356 First Aid Kit Dr. Juans Santo Remedio PARA LA ACIDEZ Basic Care Migraine Relief Care One headache relief added strength Dolodol Aspirin Backache Entrophen Ect 975mg Vanquish Entrophen Chewable TopCare Effervescent Antacid and Pain Relief Up and Up Chewable Aspirin Dolex Forte 4246 First Aid Kit 4389 First Aid Kit Aspirin Adult Low Dose ARC Emergency Preparedness FIRST AID Contains 202 PIECES Good Sense Migraine Formula Aspirin Plus Stomach Guard Ext.stgth.caplet Aspirin 81mg Enteric coated Delayed Release Alka Seltzer Plus Cold Childrens Low Dose Aspirin Adult Low strength Aspirin Nezger Tab Aspirin and Dipyridamole Medique Products Aspirin Uline Aspirin Alka-Seltzer XTRA STRENGTH pain relief back and body EXTRA STRENGTH Smart Sense Effervescent Antacid and Pain Relief Taro-dipyridamole/ Asa Enteric Coated A.S.A. Right Remedies Aspirin Low Dose 81 mg Unishield Pain Ache 4216 First Aid Kit Alka-Seltzer Plus Severe Cold Night PowerFast Fizz dihydrocodeine bitartrate and aspirin and caffeine DC Painex Tab 0.5gr 4224 First Aid Kit Anacin Caplets Sedal3x Aspergum 325 Mg (cherry) Back and Body Extra Strength Goodys Back and Body Pain BioElectro Day MEDI-FIRST Tri Buffered Aspirin Adventure Medical Kits 1-4 Person First Aid Splizz Pain Reliever - Orange-flavored Up and Up Migraine Relief WinCo Foods Effervescent Antacid and Pain Relief Bromo Seltzer Asaphen EC PMS-pharnal Tablets Medi First Plus Tri Buffered Aspirin Acetaminophen, Aspirin, Caffeine Methoxisal-C 1/2 Unishield Aspirin Berkley and Jensen Migraine Relief DG Health Effervescent Antacid and Pain Relief Aspirin 325mg 365 Everyday Value Aspirin Asadol 650mg 692 Tab 4139 First Aid Kit Low Strength Chewable Aspirin Bayer PM Asa Daily Low Dose
Indication	Pain, fever, and inflammation Acetylsalicylic acid (ASA), in the regular tablet form (immediate-release), is indicated to relieve pain, fever, and inflammation associated with many conditions, including the flu, the common cold, neck and back pain, dysmenorrhea, headache, tooth pain, sprains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, and various injuries. It is also used for symptomatic pain relief after surgical and dental procedures [FDA label]. The _extra strength_ formulation of acetylsalicylic acid is also indicated for the management migraine pain with photophobia (sensitivity to light) and phonophobia (sensitivity to sound)[FDA label]. Other indications ASA is also indicated for various other purposes, due to its ability to inhibit platelet aggregation. These include: Reducing the risk of cardiovascular death in suspected cases of myocardial infarction (MI) [FDA label]. Reducing the risk of a first non-fatal myocardial infarction in patients, and for reducing the risk of morbidity and mortality in cases of unstable angina and in those who have had a prior myocardial infarction [FDA label]. For reducing the risk of transient ischemic attacks (TIA) and to prevent atherothrombotic cerebral infarction (in conjunction with other treatments) [FDA label]. For the prevention of thromboembolism after hip replacement surgery [FDA label]. For decreasing platelet to platelet adhesion following carotid endarterectomy, aiding in the prevention of transient ischemic attacks (TIA) [FDA label]. Used for patients undergoing hemodialysis with a silicone rubber arteriovenous cannula inserted to prevent thrombosis at the insertion site [FDA Label]. Important note regarding use of the extended-release formulation [F4405] In the setting of acute myocardial infarction, or before percutaneous interventions, the extended-release form of acetylsalicylic acid should not be used. Use immediate-release formulations in scenarios requiring rapid onset of action [Label, F4405]. The extended-release form is taken to decrease the incidence of mortality and myocardial infarction (MI) for individuals diagnosed with chronic coronary artery disease (CAD), including patients with previous myocardial infarction (MI) or unstable angina or with chronic stable angina. Additionally, the extended-release form is used to decrease the risk of death and recurrent episodes of stroke in patients with a history of stroke or TIA [F4405].
Categories	Acids, Carbocyclic Agents causing angioedema Agents causing hyperkalemia Agents that produce hypertension Alimentary Tract and Metabolism Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) Antiinflammatory and Antirheumatic Products Antiplatelet agents Antipyretics Benzene Derivatives Blood and Blood Forming Organs Cardiovascular Agents Cyclooxygenase Inhibitors Cytochrome P-450 CYP2C19 Inducers Cytochrome P-450 CYP2C19 Inducers (strength unknown) Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Decreased Platelet Aggregation Decreased Prostaglandin Production Drugs that are Mainly Renally Excreted Hematologic Agents Hydroxybenzoates Musculo-Skeletal System Nephrotoxic agents Non COX-2 selective NSAIDS OAT1/SLC22A6 inhibitors OAT3/SLC22A8 Inhibitors P-glycoprotein inducers P-glycoprotein substrates Peripheral Nervous System Agents Platelet Aggregation Inhibitors Excl. Heparin Salicylates Salicylic Acid and Derivatives Sensory System Agents Stomatological Preparations UGT1A6 substrate
ATC-Code	B01AC06 C07FX04 C10BX04 M01BA03 C10BX02 N02BA71 B01AC56 N02AJ07 N02AJ02 N02BA01 B01AF51 C10BX05 N02BA51 A01AD05 C10BX01 C07FX03 N02AJ18 C10BX12 C10BX08 C10BX06 C07FX02
CAS number	50-78-2

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Prostaglandin G/H synthase 1	MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...	unknown	inhibitor
3-hydroxy-3-methylglutaryl-coenzyme A reductase	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYEC...	unknown	inhibitor
Prostaglandin G/H synthase 2	MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFY...	unknown	inhibitor
Aldo-keto reductase family 1 member C1	MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHID...	unknown	inhibitor
5'-AMP-activated protein kinase	MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTG...	unknown	activator
Endothelin-1 receptor	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVT...	unknown	inhibitor
Cellular tumor antigen p53	MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDI...	unknown	inducer
Endoplasmic reticulum chaperone BiP	MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRV...	unknown	inhibitor,binder
Ribosomal protein S6 kinase alpha-3	MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEI...	unknown	inhibitor
NF-kappa-B inhibitor alpha	MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQ...	unknown	inhibitor
Tumor necrosis factor-inducible gene 6 protein	MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYHREARSGKYKLT...	unknown	inhibitor,downregulator
Caspase-1	MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATV...	unknown	inhibitor,downregulator
Caspase-3	MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIII...	unknown	inhibitor,downregulator
Inhibitor of nuclear factor kappa-B kinase subunit beta	MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQEL...	unknown
Extracellular signal-regulated kinase (ERK)	MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR...	unknown
G1/S-specific cyclin-D1	MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQK...	unknown	downregulator
Myc proto-oncogene protein	MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQ...	unknown	downregulator
Proliferating cell nuclear antigen	MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQL...	unknown	downregulator
Cyclin A	-	unknown	downregulator
Sialidase-1	MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAEND...	unknown	inhibitor
Cytochrome P450 2C19	MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDV...	unknown	inducer
Cytochrome P450 2C9	MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI...	unknown	substrate
UDP-glucuronosyltransferase 1-6	MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLS...	unknown	substrate
Arylamine N-acetyltransferase 2	MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMEL...	unknown	substrate
Solute carrier family 22 member 6	MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCR...	unknown	inhibitor
ATP-dependent translocase ABCB1	MDLEGDRNGGAKKKNFFKLNNKSEKDKKEKKPTVSVFSMFRYSNWLDKLY...	unknown	substrate,inducer,modulator
Organic anion transporter 3	MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCR...	unknown	inhibitor
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL25
PubChem	2244
ChEMBL	CHEMBL25
ChEBI	CHEBI:15365
CCDC/CSD	ACSALA21, ACSALA23, ACSALA14, TAZRAO01, DIFQAK, ACSALA20, DIPJAQ, VUGMIT, ACSALA26, ACSALA15, ARIFOX, KEWNOQ, ACSALA17, ACSALA25, ACSALA01, ACSALA19, SIBYUA, ACSALA27, TAZRAO, HUNJEH, ACSALA28, SIBYUA01, ACSALA02, ACSALA08, ACSALA07, ACSALA05, ACSALA03, ACSALA04, ACSALA06, ACSALA11, ACSALA09, SIBYUA02, ACSALA29, GARYEH, HAPCOU
COD	4100978, 1515581, 1515582, 1516479, 1516480, 1516481, 2104857, 7050897, 7050898, 7050899, 7050901, 7050900, 7050902, 7050903