ARG

ARGININE

Find entries where: ARG

is present as a standalone ligand in 260 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 14 entries

is present in a polymer sequence 219,943 entries

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Chemical Component Summary
Name	ARGININE
Identifiers	[amino-[[(4S)-4-amino-5-hydroxy-5-oxo-pentyl]amino]methylidene]azanium
Formula	C₆ H₁₅ N₄ O₂
Molecular Weight	175.209
Type	L-PEPTIDE LINKING
Isomeric SMILES	C(C[C@@H](C(=O)O)N)CNC(=[NH2+])N
InChI	InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/p+1/t4-/m0/s1
InChIKey	ODKSFYDXXFIFQN-BYPYZUCNSA-O

Chemical Details
Formal Charge	1
Atom Count	27
Chiral Atom Count	1
Bond Count	26
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB00125 ?
Name	Arginine
Groups	investigational nutraceutical
Description	An essential amino acid that is physiologically active in the L-form.
Synonyms	(S)-2-amino-5-guanidinopentanoic acid Arg Arginine hydrochloride L-arginine (2S)-2-amino-5-(carbamimidamido)pentanoic acid L-Arginin Arginina (2S)-2-amino-5-guanidinopentanoic acid Arginine (S)-2-Amino-5-guanidinovaleric acid L-Arg Arginine butyrate R L-(+)-Arginine
Brand Names	R-Gene Olimel 5.7% 20% Prosol Hypertenipine Essepna 8.5% Freamine III Aminosyn 10% W Electrolytes Aminosyn II 10% With Electrolytes Aminosyn 5% Aminosyn II in Dextrose Lysakare Aminosyn II 7% Injection Olimel 7.6% E ProSol Travasol Amino Acid Inj 5.5% Moisture Cushion Travasol Inj Without Electrolytes 5.5% Aminosyn II 7% M In 10% Dextrose(dual Chamber) Rimantalist 4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix Aminosyn II 8.5% With 50% Dextrose Kabiven 2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix Vamin N Lytensopril-90 FreAmine HBC Perikabiven Aminosyn II and Dextrose 4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose HepatAmine Aminosyn II 7% With 50% Dextrose Lytensopril 2.75% Travas. Amino Acid InJ.W.elecw.25%dex ProcalAmine Aminosyn II 8.5% Injection FreAmine III Olimel 4.4% Clinimix Aminosyn II 5% Inj Clinimix E Olimel 7.6% 2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix Aminosyn 3.5% M Aminosyn-PF 4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose L-arginine Hydrochloride Injection Aminosyn II Aminosyn II with Electrolytes Aminosyn Hepatasol Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) Synthamin Plenamine Aminosyn II with Electrolytes in Dextrose with Calcium Smofkabiven Extra Nitrogen Electrolyte Free 4.25%trav. Amino Acid InJ.W.O.elect.5%dext. 4.25%travasol Amino Acid InJ.W.elecw.5%dex. Aminosyn Sulfite Free Clinisol Vamin 18 Electrolyte-free Travasol Inj Without Electrolytes 8.5% Premasol - sulfite-free (Amino Acid) Olimel 4.4% E Primene 10%-liq IV Aminosyn-PF 10% tensioSAN Primene Hypertensolol Novamine 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix Periolimel 2.5% E 4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix Cardiotek-RX Aminosyn 8.5% Aminosyn RF Injection 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Travasol Amino Acid Inj 8.5% 5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose Travasol Nutrineal Pd4 Olimel 3.3% E Aminosyn-PF 7% Cream Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec 4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix 4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose Aminosyn HF Aminosyn 7% 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Olimel 5.7% E Smofkabiven Aminosyn II In Dextrose Injection 5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose Repair Vaginal Aminosyn 8.5% Injection With Electrolytes 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose 2.5%travasol Amino Acid InJ.W.eleC.W.25%dex 4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Smofkabiven Electrolyte Free 2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix Smofkabiven Extra Nitrogen Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec Arginine 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex. Primene 10% Travasol E Renamin (amino Acids) Injection Aminosyn II 7% With 10% Dextrose Aminosyn RF TrophAmine Smofkabiven Peripheral 4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose RenAmin Hypertenevide-12.5
Indication	Used for nutritional supplementation, also for treating dietary shortage or imbalance.
Categories	Acids, Acyclic Amino Acids Amino Acids, Basic Amino Acids, Diamino Amino Acids, Peptides, and Proteins Arginine Blood and Blood Forming Organs Blood Substitutes and Perfusion Solutions Detoxifying Agents for Antineoplastic Treatment Dietary Supplements Fatty Acids Fatty Acids, Volatile I.V. Solution Additives Lipids Pituitary Function Proteinogenic Amino Acids Supplements
ATC-Code	V03AF11 B05XB01
CAS number	74-79-3

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Cationic amino acid transporter 3	MPWQAFRRFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGV...	unknown
Arginine decarboxylase	MAGYLSESDFVMVEEGFSTRDLLKELTLGASQATTDEVAAFFVADLGAIV...	unknown
Argininosuccinate lyase	MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLE...	unknown
Nitric oxide synthase, inducible	MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLS...	unknown
High affinity cationic amino acid transporter 1	MGCKVLLNIGQQMLRRKVVDCSREETRLSRCLNTFDLVALGVGSTLGAGV...	unknown
Arginase-2, mitochondrial	MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIR...	unknown
Cationic amino acid transporter 4	MARGLPTIASLARLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGM...	unknown
Argininosuccinate synthase	MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKK...	unknown
Nitric oxide synthase, endothelial	MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAP...	unknown
Solute carrier family 22 member 5	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Monocarboxylate transporter 10	MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVEL...	unknown	inhibitor
Solute carrier family 22 member 4	MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRC...	unknown	inhibitor
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	5287702, 1549073, 52941769, 59294017, 59904234, 88031296
ChEBI	CHEBI:32682
CCDC/CSD	GELHIO10, NABSIT, INEFIQ01, HAHBIC01, REHTII, BOQVIM01, PEVCUR, ORUXEF, NABQAJ, EGIVOH, ARGBRH02, MOSRAQ, HAHBIC, NABSOZ, EGIVUN, EGIVIB, ADIHOL, BOQVIM, QIJZEQ, MACMUC
COD	2209573

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

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ARG

ARGININE

Chemical Component Summary

Chemical Details

Drug Info: DrugBank

Drug Targets

Related Resource References