AZ5
5-CHLORO-N2-[(1S)-1-(5-FLUOROPYRIMIDIN-2-YL)ETHYL]-N4-(5-METHYL-1H-PYRAZOL-3-YL)PYRIMIDINE-2,4-DIAMINE
Find entries where: AZ5
is present as a standalone ligand in 1 entries
Chemical Component Summary | |
|---|---|
| Name | 5-CHLORO-N2-[(1S)-1-(5-FLUOROPYRIMIDIN-2-YL)ETHYL]-N4-(5-METHYL-1H-PYRAZOL-3-YL)PYRIMIDINE-2,4-DIAMINE |
| Identifiers | 5-chloro-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N'-(5-methyl-2H-pyrazol-3-yl)pyrimidine-2,4-diamine |
| Formula | C14 H14 Cl F N8 |
| Molecular Weight | 348.766 |
| Type | NON-POLYMER |
| Isomeric SMILES | Cc1cc([nH]n1)Nc2c(cnc(n2)N[C@@H](C)c3ncc(cn3)F)Cl |
| InChI | InChI=1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24)/t8-/m0/s1 |
| InChIKey | PDOQBOJDRPLBQU-QMMMGPOBSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 38 |
| Chiral Atom Count | 1 |
| Bond Count | 40 |
| Aromatic Bond Count | 17 |
Drug Info: DrugBank
| DrugBank ID | DB12588? |
|---|---|
| Name | AZD-1480 |
| Groups | investigational |
| Description | AZD1480 has been used in trials studying the treatment of Solid Malignancies, Post-Polycythaemia Vera, Primary Myelofibrosis (PMF), and Essential Thrombocythaemia Myelofibrosis. |
| Synonyms | AZD-1480 |
| Categories |
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| CAS number | 935666-88-9 |
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL1231124 |
| PubChem | 16659841 |
| ChEMBL | CHEMBL1231124 |
