AZG

5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL

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is present as a standalone ligand in 7 entries

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Chemical Component Summary
Name	5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL
Synonyms	8-AZAGUANINE
Identifiers	5-amino-1H-[1,2,3]triazolo[5,4-e]pyrimidin-7-ol
Formula	C₄ H₄ N₆ O
Molecular Weight	152.114
Type	NON-POLYMER
Isomeric SMILES	c12c(nc(nc1O)N)nn[nH]2
InChI	InChI=1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)
InChIKey	LPXQRXLUHJKZIE-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	15
Chiral Atom Count	0
Bond Count	16
Aromatic Bond Count	10

Drug Info: DrugBank

DrugBank ID	DB01667 ?
Name	8-azaguanine
Groups	experimental
Description	8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
Synonyms	8 AG Guanazol Azaguanine-8 Pathocidine 8-azaguanine Azaguanine 3-amino-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one Pathocidin
Categories	Antimetabolites Antineoplastic Agents Aza Compounds Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 Substrates Heterocyclic Compounds, Fused-Ring Noxae Purines Purinones Toxic Actions Xanthine derivatives
CAS number	134-58-7

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Purine nucleoside phosphorylase	MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDY...	unknown
Cytochrome P450 1A2	MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPL...	unknown	substrate

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682