BC3

2-amino-7-(pyridin-3-ylmethyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one

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is present as a standalone ligand in 1 entries

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Chemical Component Summary
Name	2-amino-7-(pyridin-3-ylmethyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Synonyms	peldesine,BCX-34
Identifiers	2-amino-7-(pyridin-3-ylmethyl)-3,5-dihydropyrrolo[2,3-e]pyrimidin-4-one
Formula	C₁₂ H₁₁ N₅ O
Molecular Weight	241.249
Type	NON-POLYMER
Isomeric SMILES	c1cc(cnc1)Cc2c[nH]c3c2N=C(NC3=O)N
InChI	InChI=1S/C12H11N5O/c13-12-16-9-8(4-7-2-1-3-14-5-7)6-15-10(9)11(18)17-12/h1-3,5-6,15H,4H2,(H3,13,16,17,18)
InChIKey	DOHVAKFYAHLCJP-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	29
Chiral Atom Count	0
Bond Count	31
Aromatic Bond Count	11

Drug Info: DrugBank

DrugBank ID	DB02568 ?
Name	Peldesine
Groups	investigational
Description	Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.
Synonyms	2-Amino-3,5-dihydro-7-(3-pyridylmethyl)-4H-pyrrolo(3,2-d)pyrimidin-4-one Peldesine
Categories	Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 Substrates Heterocyclic Compounds, Fused-Ring N-Glycosyl Hydrolases, antagonists & inhibitors Purines Purinones Xanthine derivatives
CAS number	133432-71-0

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Purine nucleoside phosphorylase	MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDY...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682