BEZ
BENZOIC ACID
Find entries where: BEZ
is present as a standalone ligand in 184 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 5 entries
is present in a polymer sequence 17 entries
Chemical Component Summary | |
|---|---|
| Name | BENZOIC ACID |
| Identifiers | benzoic acid |
| Formula | C7 H6 O2 |
| Molecular Weight | 122.121 |
| Type | NON-POLYMER |
| Isomeric SMILES | c1ccc(cc1)C(=O)O |
| InChI | InChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9) |
| InChIKey | WPYMKLBDIGXBTP-UHFFFAOYSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 15 |
| Chiral Atom Count | 0 |
| Bond Count | 15 |
| Aromatic Bond Count | 6 |
Drug Info: DrugBank
| DrugBank ID | DB03793? |
|---|---|
| Name | Benzoic acid |
| Groups |
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| Description | A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads to excretion of these amino acids and a decrease in ammonia levels. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo. |
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| ATC-Code |
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| CAS number | 65-85-0 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Solute carrier family 15 member 1 | MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDN... | unknown | |
| Cocaine esterase | MVDGNYSVASNVMVPMRDGVRLAVDLYRPDADGPVPVLLVRNPYDKFDVF... | unknown | product of |
| D-amino-acid oxidase | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAG... | unknown | |
| Chlorocatechol 1,2-dioxygenase | MANTRVIELFDEFTDLIRDFIVRHEITTPEYETIMQYMISVGEAGEWPLW... | unknown | substrate |
| 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase | MANLEIGKSILAAGVLTNYHDVGEGQPVILIHGSGPGVSAYANWRLTIPA... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL541 |
| PubChem | 20144841, 243 |
| ChEMBL | CHEMBL541 |
| ChEBI | CHEBI:30746 |
| CCDC/CSD | AFEREK, CUPCEY, AYUNUE, DUYWAV, EMOCUF, BUCCAG, BENZAC12, BUDWEC, CUCSEY10, CUSSOZ, DIKDOR, DAWKIX, BENZAC21, CILLEQ, CILMAN, DUPJEE, CICZUL, CILLOA, DOGBAF, CUCSEY01, EZOLOW, EXEYOW, EJOKAR, BENZAC20, COZXOF, COZXIZ, EJOKAR01, AWESUR, EJOKAR02, EZIFID, DUTSOB, COZXUL, EMOCOZ, EQOPUV, EBUZAG |
| COD | 7200221, 7200222, 7200223, 7215557, 7215558, 7215559, 7210454, 2225365, 2225405 |
