CLR
CHOLESTEROL
Find entries where: CLR
is present as a standalone ligand in 820 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 12 entries
is present in a polymer sequence 1 entries
Chemical Component Summary | |
|---|---|
| Name | CHOLESTEROL |
| Identifiers | (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol |
| Formula | C27 H46 O |
| Molecular Weight | 386.654 |
| Type | NON-POLYMER |
| Isomeric SMILES | CC(C)CCC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C |
| InChI | InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1 |
| InChIKey | HVYWMOMLDIMFJA-DPAQBDIFSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 74 |
| Chiral Atom Count | 8 |
| Bond Count | 77 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB04540? |
|---|---|
| Name | Cholesterol |
| Groups |
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| Description | The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. |
| Synonyms |
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| Categories |
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| CAS number | 57-88-5 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Nuclear receptor subfamily 1 group I member 3 | MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA... | unknown | |
| Vitamin D3 receptor | MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR... | unknown | |
| C-type lectin domain family 4 member E | MNSSKSSETQCTERGCFSSQMFLWTVAGIPILFLSACFITRCVVTFRIFQ... | unknown | ligand |
| Nuclear receptor ROR-alpha | MESAPAAPDPAASEPGSSGADAAAGSRETPLNQESARKSEPPAPVRRQSY... | unknown | |
| P-glycoprotein 1 | MDLEGDRNGGAKKKNFFKLNNKSEKDKKEKKPTVSVFSMFRYSNWLDKLY... | unknown | inhibitor |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL112570 |
| PubChem | 5997 |
| ChEMBL | CHEMBL112570 |
| ChEBI | CHEBI:140435, CHEBI:16113 |
| COD | 4502852, 4502851, 7110257 |
