DTT
2,3-DIHYDROXY-1,4-DITHIOBUTANE
Find entries where: DTT
is present as a standalone ligand in 224 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 94 entries
Chemical Component Summary | |
|---|---|
| Name | 2,3-DIHYDROXY-1,4-DITHIOBUTANE |
| Synonyms | 1,4-DITHIOTHREITOL |
| Identifiers | (2R,3R)-1,4-bis-sulfanylbutane-2,3-diol |
| Formula | C4 H10 O2 S2 |
| Molecular Weight | 154.251 |
| Type | NON-POLYMER |
| Isomeric SMILES | C([C@@H]([C@H](CS)O)O)S |
| InChI | InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1 |
| InChIKey | VHJLVAABSRFDPM-IMJSIDKUSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 18 |
| Chiral Atom Count | 2 |
| Bond Count | 17 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB04447? |
|---|---|
| Name | 1,4-Dithiothreitol |
| Groups | experimental |
| Description | A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols. [PubChem] |
| Synonyms |
|
| CAS number | 3483-12-3 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Thymidylate synthase | MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRC... | unknown | |
| Triosephosphate isomerase | MAEDGEEAEFHFAALYISGQWPRLRADTDLQRLGSSAMAPSRKFFVGGNW... | unknown | |
| Maleylacetoacetate isomerase | MQAGKPILYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDRGQQFSKDF... | unknown | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYEC... | unknown | |
| Listeriolysin regulatory protein | MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTS... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 439196 |
| ChEMBL | CHEMBL406270 |
| ChEBI | CHEBI:42106 |
