DUR
2'-DEOXYURIDINE
Find entries where: DUR
is present as a standalone ligand in 17 entries
is present in a polymer sequence 1 entries
Chemical Component Summary | |
|---|---|
| Name | 2'-DEOXYURIDINE |
| Identifiers | 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| Formula | C9 H12 N2 O5 |
| Molecular Weight | 228.202 |
| Type | NON-POLYMER |
| Isomeric SMILES | C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O |
| InChI | InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1 |
| InChIKey | MXHRCPNRJAMMIM-SHYZEUOFSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 28 |
| Chiral Atom Count | 3 |
| Bond Count | 29 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB02256? |
|---|---|
| Name | 2'-Deoxyuridine |
| Groups | experimental |
| Description | 2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. [PubChem] |
| Synonyms | 2'-Deoxyuridine |
| CAS number | 951-78-0 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Uridine phosphorylase | MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLAShref... | unknown | |
| Thymidylate synthase | MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRC... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 13712 |
| ChEMBL | CHEMBL353955 |
| ChEBI | CHEBI:16450 |
| CCDC/CSD | DOURID |
