DXX
METHYLMALONIC ACID
Find entries where: DXX
is present as a standalone ligand in 5 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 4 entries
Chemical Component Summary | |
|---|---|
| Name | METHYLMALONIC ACID |
| Identifiers | 2-methylpropanedioic acid |
| Formula | C4 H6 O4 |
| Molecular Weight | 118.088 |
| Type | NON-POLYMER |
| Isomeric SMILES | CC(C(=O)O)C(=O)O |
| InChI | InChI=1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8) |
| InChIKey | ZIYVHBGGAOATLY-UHFFFAOYSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 14 |
| Chiral Atom Count | 0 |
| Bond Count | 13 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB04183? |
|---|---|
| Name | Methylmalonic Acid |
| Groups | experimental |
| Description | A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA. [PubChem] |
| Synonyms | Methylmalonic Acid |
| Categories |
|
| CAS number | 516-05-2 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Methylmalonyl-CoA carboxyltransferase 12S subunit | MAENNNLKLASTMEGRVEQLAEQRQVIEAGGGERRVEKQHSQGKQTARER... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 487 |
| ChEMBL | CHEMBL1232416 |
| ChEBI | CHEBI:30860 |
| CCDC/CSD | MEMALA01, MEMALA, PAYXUM |
