GDP
GUANOSINE-5'-DIPHOSPHATE
Find entries where: GDP
is present as a standalone ligand in 2,054 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 35 entries
is present in a polymer sequence 37 entries
Chemical Component Summary | |
|---|---|
| Name | GUANOSINE-5'-DIPHOSPHATE |
| Identifiers | [(2R,3S,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate |
| Formula | C10 H15 N5 O11 P2 |
| Molecular Weight | 443.201 |
| Type | RNA LINKING |
| Isomeric SMILES | c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N |
| InChI | InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1 |
| InChIKey | QGWNDRXFNXRZMB-UUOKFMHZSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 43 |
| Chiral Atom Count | 4 |
| Bond Count | 45 |
| Aromatic Bond Count | 5 |
Drug Info: DrugBank
| DrugBank ID | DB04315? |
|---|---|
| Name | Guanosine-5'-Diphosphate |
| Groups | experimental |
| Description | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. [PubChem] |
| Synonyms | Guanosine-5'-Diphosphate |
| CAS number | 146-91-8 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| GTPase HRas | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGET... | unknown | |
| Transforming protein RhoA | MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDG... | unknown | |
| Protein-glutamine gamma-glutamyltransferase 2 | MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNY... | unknown | |
| Ras-related protein Rab-11A | MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFAT... | unknown | |
| Adenylosuccinate synthetase | MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEK... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL384759 |
| PubChem | 135398619, 8977, 5280316 |
| ChEMBL | CHEMBL384759 |
| ChEBI | CHEBI:17552 |
