GLY

GLYCINE

Find entries where: GLY

is present as a standalone ligand in 405 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 60 entries

is present in a polymer sequence 221,996 entries

Find related ligands:

Similar Ligands (Stereospecific)

Similar Ligands (Quick Screen)

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	GLYCINE
Identifiers	2-aminoethanoic acid
Formula	C₂ H₅ N O₂
Molecular Weight	75.067
Type	PEPTIDE LINKING
Isomeric SMILES	C(C(=O)O)N
InChI	InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKey	DHMQDGOQFOQNFH-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	10
Chiral Atom Count	0
Bond Count	9
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB00145 ?
Name	Glycine
Groups	approved nutraceutical vet_approved
Description	A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Synonyms	Glicina Aminoessigs?ure Aminoacetic acid Glycin Aminoethanoic acid Glycine Glyzin Glykokoll Glycocoll Leimzucker Gly
Brand Names	Primene 10% Essepna Aminosyn II 7% With 50% Dextrose Aminosyn II 7% M In 10% Dextrose(dual Chamber) Travasol Amino Acid Inj 5.5% Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec Aminosyn 7% 5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose Aminosyn II and Dextrose Renamin (amino Acids) Injection Smofkabiven Electrolyte Free Glycine 1.5% Irrigation USP Sol ProcalAmine Aminosyn II 7% With 10% Dextrose 2.5%travasol Amino Acid InJ.W.eleC.W.25%dex Aminosyn-PF 4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix Clinisol Primene 10%-liq IV FreAmine III Aminosyn 8.5% Kabiven Synthamin Travasol Inj Without Electrolytes 5.5% Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec Olimel 4.4% E 4.25%trav. Amino Acid InJ.W.O.elect.5%dext. Premasol - sulfite-free (Amino Acid) Travasol E Periolimel 2.5% E Vamin 18 Electrolyte-free Aminosyn II 10% With Electrolytes Novamine Glycine Irrigation USP Sterile Diluent for Flolan Injection 2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix 4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose TrophAmine 4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose Olimel 4.4% Travasol Amino Acid Inj 8.5% 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix Antacid 2 Tablets Aminosyn-PF 10% Aminosyn II with Electrolytes in Dextrose with Calcium Glycine Irrigation 1.5% USP Smofkabiven Peripheral 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix 4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix Olimel 7.6% Clinimix E Aminosyn II 8.5% With 50% Dextrose Glycine Aminosyn II in Dextrose Perikabiven Ph 12 Sterile Diluent for Flolan Hepatasol Aminosyn HF ProSol Travasol Aminosyn 5% Aminosyn II 7% Injection CAREDO Repair Cracked Teeth Toothpastes 100g Aminosyn II with Electrolytes Plenamine Aminosyn 8.5% Injection With Electrolytes Olimel 5.7% E Smofkabiven Vamin N Nutrineal Pd4 4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Aminosyn 3.5% M Primene HepatAmine Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) Aminosyn Aminosyn II In Dextrose Injection 2.75% Travas. Amino Acid InJ.W.elecw.25%dex Smofkabiven Extra Nitrogen Electrolyte Free 4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Aminosyn II 2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix RenAmin FreAmine HBC Olimel 7.6% E 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Travasol Inj Without Electrolytes 8.5% 4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix BANACOCica-aid Centella Peptide emulsion Aminosyn 10% W Electrolytes 2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix Olimel 5.7% Aminoderm Poudre CAREDO Treating Gingivitis Toothpastes 100g Cicatrin Powder Aminosyn II 5% Inj Clinimix 20% Prosol Aminosyn-PF 7% 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose 4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose Olimel 3.3% E Smofkabiven Extra Nitrogen 8.5% Freamine III Aminosyn II 8.5% Injection 5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose Aminosyn Sulfite Free 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex. 4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Indication	Supplemental glycine may have antispastic activity. Very early findings suggest it may also have antipsychotic activity as well as antioxidant and anti-inflammatory activities.
Categories	Amino Acids Amino Acids, Peptides, and Proteins Blood and Blood Forming Organs Blood Substitutes and Perfusion Solutions Dietary Supplements Glycine Agents Irrigating Solutions Neurotransmitter Agents Proteinogenic Amino Acids Supplements
ATC-Code	B05CX03
CAS number	56-40-6

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial	MWPGNAWRAALFWVPRGRRAQSALAQLRGILEGELEGIRGAGTWKSERVI...	unknown	substrate
5-aminolevulinate synthase, nonspecific, mitochondrial	MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALST...	unknown	substrate
5-aminolevulinate synthase, erythroid-specific, mitochondrial	MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQ...	unknown	substrate
Glycine--tRNA ligase	MPSPRPVLLRGARAALLLLLPPRLLARPSLLLRRSLSAASCPPISLPAAA...	unknown	substrate
Glutamate receptor ionotropic, NMDA 2A	MGRVGYWTLLVLPALLVWRGPAPSAAAEKGPPALNIAVMLGHSHDVTERE...	unknown	antagonist
Bile acid-CoA:amino acid N-acyltransferase	MIQLTATPVSALVDEPVHIRATGLIPFQMVSFQASLEDENGDMFYSQAHY...	unknown	substrate
N-arachidonyl glycine receptor	MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCT...	unknown	substrate
Glutathione synthetase	MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPF...	unknown	substrate
Glutamate receptor ionotropic, NMDA 2C	MGGALGPALLLTSLFGAWAGLGPGQGEQGMTVAVVFSSSGPPQAQFRARL...	unknown	agonist
Serine hydroxymethyltransferase	MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLS...	unknown	product of
Glycine N-acyltransferase	MMLPLQGAQMLQMLEKSLRKSLPASLKVYGTVFHINHGNPFNLKAVVDKW...	unknown	substrate
Serine hydroxymethyltransferase, mitochondrial	MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLS...	unknown	product of
Glycine N-acyltransferase-like protein 2	MLVLHNSQKLQILYKSLEKSIPESIKVYGAIFNIKDKNPFNMEVLVDAWP...	unknown	substrate
Glycine N-acyltransferase-like protein 1	MILLNNSHKLLALYKSLARSIPESLKVYGSVYHINHGNPFNMEVLVDSWP...	unknown	substrate
Alanine--glyoxylate aminotransferase 2, mitochondrial	MTLIWRHLLRPLCLVTSAPRILEMHPFLSLGTSRTSVTKLSLHTKPRMPP...	unknown	product of
Peroxisomal sarcosine oxidase	MAAQKDLWDAIVIGAGIQGCFTAYHLAKHRKRILLLEQFFLPHSRGSSHG...	unknown	product of
Glutamate receptor ionotropic, NMDA 3B	MEFVRALWLGLALALGPGSAGGHPQPCGVLARLGGSVRLGALLPRAPLAR...	unknown	substrate
Glycine receptor subunit alpha-1	MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTS...	unknown	ligand
Serine--pyruvate aminotransferase	MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMS...	unknown	substrate
Glycine receptor subunit beta	MKFLLTTAFLILISLWVEEAYSKEKSSKKGKGKKKQYLCPSQQSAEDLAR...	unknown	ligand
Serine hydroxymethyltransferase, cytosolic	MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLEL...	unknown	product of
Glycine receptor subunit alpha-3	MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKL...	unknown	ligand
Glycine receptor subunit alpha-2	MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDK...	unknown	ligand
Glycine N-methyltransferase	MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLL...	unknown	substrate
Glycine amidinotransferase, mitochondrial	MLRVRCLRGGSRGAEAVHYIGSRLGRTLTGWVQRTFQSTQAATASSRNSC...	unknown	substrate
Aminomethyltransferase, mitochondrial	MQRAVSVVARLGFRLQAFPPALCRPLSCAQEVLRRTPLYDFHLAHGGKMV...	unknown	substrate
Glycine dehydrogenase [decarboxylating], mitochondrial	MQSCARAWGLRLGRGVGGGRRLAGGSGPCWAPRSRDSSSGGGDSAAAGAS...	unknown	substrate
Dihydrolipoyl dehydrogenase, mitochondrial	MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSG...	unknown	substrate
Glycine cleavage system H protein, mitochondrial	MALRVVRSVRALLCTLRAVPSPAAPCPPRPWQLGVGAVRTLRTGPALLSV...	unknown	substrate
Monocarboxylate transporter 10	MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVEL...	unknown	substrate,inhibitor
Proton-coupled amino acid transporter 1	MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWF...	unknown	substrate
Vesicular inhibitory amino acid transporter	MATLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDL...	unknown	substrate
Sodium- and chloride-dependent glycine transporter 2	MDCSAPKEMNKLPANSPEAAAAQGHPDGPCAPRTSPEQELPAAAAPPPPR...	unknown	substrate
Sodium- and chloride-dependent glycine transporter 1	MSGGDTRAAIARPRMAAAHGPVAPSSPEQVTLLPVQRSFFLPPFSGATPS...	unknown	substrate
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682