GTP
GUANOSINE-5'-TRIPHOSPHATE
Find entries where: GTP
is present as a standalone ligand in 1,492 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 85 entries
is present in a polymer sequence 250 entries
Chemical Component Summary | |
|---|---|
| Name | GUANOSINE-5'-TRIPHOSPHATE |
| Identifiers | [[(2R,3S,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate |
| Formula | C10 H16 N5 O14 P3 |
| Molecular Weight | 523.18 |
| Type | NON-POLYMER |
| Isomeric SMILES | c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N |
| InChI | InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1 |
| InChIKey | XKMLYUALXHKNFT-UUOKFMHZSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 48 |
| Chiral Atom Count | 4 |
| Bond Count | 50 |
| Aromatic Bond Count | 5 |
Drug Info: DrugBank
| DrugBank ID | DB04137? |
|---|---|
| Name | Guanosine-5'-Triphosphate |
| Groups | experimental |
| Description | Guanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem] |
| Synonyms | Guanosine-5'-Triphosphate |
| CAS number | 86-01-1 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| RNA-directed RNA polymerase | MPRRAPAFPLSDIKAQMLFANNIKAQQASKRSFKEGAIETYEGLLSVDPR... | unknown | |
| Uridine-cytidine kinase-like 1 | MAAPPARADADPSPTSPPTARDTPGRQAEKSETACEDRSNAESLDRLLPP... | unknown | |
| GTPase HRas | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGET... | unknown | |
| Genome polyprotein | MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRAPR... | unknown | |
| Rho-related GTP-binding protein RhoE | MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPE... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL1233147 |
| PubChem | 135398633, 6830, 5280317 |
| ChEMBL | CHEMBL1233147 |
| ChEBI | CHEBI:15996 |
