HQY

quinolin-8-ol

Created:	2009-10-28
Last modified:	2024-09-27

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2 entries where HQY is found as a standalone ligand1 entries where HQY is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	18
Chiral Atom Count	0
Bond Count	19
Aromatic Bond Count	11

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Chemical Component Summary
Name	quinolin-8-ol
Synonyms	8-hydroxyquinoline
Systematic Name (OpenEye OEToolkits)	quinolin-8-ol
Formula	C₉ H₇ N O
Molecular Weight	145.158
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	11.02	Oc1cccc2cccnc12
SMILES	CACTVS	3.352	Oc1cccc2cccnc12
SMILES	OpenEye OEToolkits	1.7.0	c1cc2cccnc2c(c1)O
Canonical SMILES	CACTVS	3.352	Oc1cccc2cccnc12
Canonical SMILES	OpenEye OEToolkits	1.7.0	c1cc2cccnc2c(c1)O
InChI	InChI	1.03	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
InChIKey	InChI	1.03	MCJGNVYPOGVAJF-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB11145 ?
Name	Oxyquinoline
Groups	approved vet_approved
Description	Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Synonyms	oxine 8-Hydroxyquinoline citrate Phenopyridine 8-Hydroxyquinoline hydrochloride Oxyquinoline 8-Hydroxyquinoline sulfate 8-Hydroxyquinoline salicylate hydroxybenzopyridine 8-Hydroxyquinoline Oxyquinoline sulfate Hydroxyquinoline
Brand Names	Arkodyne Trimo San Deodorant Vaginal Jelly Trimo-San Sulpak II Trimo San New Skin Clear Liquid Bandage Racestyptine Cord Fem pH Relegard Racestyptine Sol New Skin Clear Spray Bandage
Indication	Oxyquinoline is used as a biocidal component of several over the counter products. These products are marketed for the purposes of inhibiting abnormal biological growth in the vagina and restoring natural pH.
Categories	Alimentary Tract and Metabolism Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment Antiseptics and Disinfectants Dermatologicals Drugs that are Mainly Renally Excreted Genito Urinary System and Sex Hormones Gynecological Antiinfectives and Antiseptics Heterocyclic Compounds, Fused-Ring Hydroxyquinolines Quinoline Derivatives Quinolines Stomatological Preparations Throat Preparations
ATC-Code	R02AA14 A01AB07 D08AH03 G01AC30
CAS number	148-24-3

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Methionine aminopeptidase 2	MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSA...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	1923
ChEMBL	CHEMBL310555
ChEBI	CHEBI:48981
CCDC/CSD	HXQUIN13, HXQUIN16, HXQUIN17, HXQUIN11, HXQUIN14, GAHHUT, HXQUIN03, HXQFOW10, HXQUIN10, HQUNBZ, HXQFNB10, DOXCEA
COD	7229766, 2239864, 2208696