HSM

HISTAMINE

Find entries where: HSM

is present as a standalone ligand in 42 entries

Find related ligands:

Chemical Component Summary
Name	HISTAMINE
Identifiers	2-(1H-imidazol-4-yl)ethanamine
Formula	C₅ H₉ N₃
Molecular Weight	111.145
Type	NON-POLYMER
Isomeric SMILES	c1c(nc[nH]1)CCN
InChI	InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChIKey	NTYJJOPFIAHURM-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	17
Chiral Atom Count	0
Bond Count	17
Aromatic Bond Count	5

Drug Info: DrugBank

DrugBank ID	DB05381 ?
Name	Histamine
Groups	approved investigational
Description	A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Synonyms	beta-aminoethylimidazole 1H-Imidazole-4-ethanamine beta-aminoethylglyoxaline Histamine 2-(4-imidazolyl)ethylamine Histamine phosphate 4-imidazoleethylamine 5-imidazoleethylamine Histamine dihydrochloride
Brand Names	Arthritis Pain Relief Cream Bakers Best Arthritis Pain Relief Arthritis Relief Royal Labs Hemp Recover Histamine Phosphate Injection USP, 1mg/ml Alo Therapeutic Massage Pain Relieving Australian Dream Pain Relieving Arthritis CVS Arthritis Pain Relief Australian Dream Back Pain PainMD Max Minted Leaf Odorless Pain Relief TerraFreeze Pain Relief Bakers Best Arthritis Pain Relief with Hemp Seed Md Science Cannabidiol Md Science Cannabigerol DR. MIKES Ponos Pain Relief Cream Roll-On Simanix REVIVE SCIENCE Natural Hemp Pain Relief Rub Alo Therapeutic Massage HAVASU HEMP Soothing Pain Relief Rub Pain Relieving Arthritis Arthrocare Lotion Histamine Phosphate Injection USP Liq Sc BAKERS BEST Arthritis Pain Relief Cream with Hemp and Lavender Midalgan Mancore Muscle Mend Roll-ON Pain Reliever Arthritis Pain Relief AMINO ACTIVE Topical Analgesic Cream Positive Skin Test Control - Histamine MINTED LEAF Odorless Histamine DHCl Pain Relief and Hemp Extract Glucosamine Cream EXTRA STRENGTH Histatrol MUSCLESHOK Sport Ponos Natural Pain Relief Walgreens Arthritis Pain Relief Cream Histamine DHCl 0.10 Percent Camphomex Positive Skin Test Control-histamine ROPANA Pain Relief Cream Australian Dream Carpal Tunnel Pain Histamine Positive Skin Test Control Raging Kakapo Pain Relieve Abee Med Rematex Australian Dream Hand and Wrist Pain Histamine DHCl 0.10 Percent and Menthol 2 Percent Ceplene ActivOn Ultra Strength Arthritis Dr. Freds MIRACLE RUB MUSCLESHOK Back Pain Hand and Wrist Pain Cream
Indication	Histamine phosphate is indicated as a diagnostic aid for the evaluation of gastric acid secretory function.
Categories	Adjuvants, Immunologic Amines Antineoplastic and Immunomodulating Agents Autacoids Biogenic Amines Biogenic Monoamines Biological Factors Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 Enzyme Inhibitors Diagnostic Agents Ethylamines Gastric Function Histamine Agents Histamine Agonists Imidazoles Inflammation Mediators Neurotransmitter Agents OCT1 substrates OCT2 Inhibitors OCT2 Substrates Other Diagnostics Tests for Gastric Secretion
ATC-Code	L03AX14 V04CG03
CAS number	51-45-6

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Histamine H1 receptor	MSLPNSSCLLEDKMCEGNKTTMASPQLMPLVVVLSTICLVTVGLNLLVLY...	unknown	agonist
Histamine H2 receptor	MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLR...	unknown	agonist
Histamine H3 receptor	MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVL...	unknown	agonist
Histamine H4 receptor	MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRS...	unknown	agonist
Synaptic vesicular amine transporter	MALSELALVRWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYS...	unknown
Histamine N-methyltransferase	MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDT...	unknown	substrate
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	substrate,inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown
Solute carrier family 22 member 3	MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYW...	unknown	inhibitor
Solute carrier family 22 member 5	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682