I3P
D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
Find entries where: I3P
is present as a standalone ligand in 59 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 1 entries
Chemical Component Summary | |
|---|---|
| Name | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE |
| Identifiers | [(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-diphosphonooxy-cyclohexyl] dihydrogen phosphate |
| Formula | C6 H15 O15 P3 |
| Molecular Weight | 420.096 |
| Type | NON-POLYMER |
| Isomeric SMILES | [C@H]1([C@@H]([C@H]([C@@H]([C@H]([C@@H]1OP(=O)(O)O)O)OP(=O)(O)O)OP(=O)(O)O)O)O |
| InChI | InChI=1S/C6H15O15P3/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)/t1-,2+,3+,4-,5-,6-/m1/s1 |
| InChIKey | MMWCIQZXVOZEGG-XJTPDSDZSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 39 |
| Chiral Atom Count | 6 |
| Bond Count | 39 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB03401? |
|---|---|
| Name | 1D-myo-inositol 1,4,5-trisphosphate |
| Groups | experimental |
| Description | Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin. |
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| Categories |
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| CAS number | 85166-31-0 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Cytohesin-2 | MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGL... | unknown | |
| Epsin-1 | MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNV... | unknown | |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | MDSGRDFLTLHGLQDDEDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKT... | unknown | |
| Radixin | MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYV... | unknown | |
| Spectrin beta chain, non-erythrocytic 1 | MTTTVATDYDNIEIQQQYSDVNNRWDVDDWDNENSSARLFERSRIKALAD... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL279107 |
| PubChem | 439456 |
| ChEMBL | CHEMBL279107 |
| ChEBI | CHEBI:16595 |
