J60

5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE

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is present as a standalone ligand in 5 entries

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Chemical Component Summary
Name	5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE
Identifiers	5-[(Z)-(5-chloro-2-oxo-1H-indol-3-ylidene)methyl]-N-(2-diethylaminoethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Formula	C₂₂ H₂₇ Cl N₄ O₂
Molecular Weight	414.928
Type	NON-POLYMER
Isomeric SMILES	CCN(CC)CCNC(=O)c1c(c([nH]c1C)\C=C/2\c3cc(ccc3NC2=O)Cl)C
InChI	InChI=1S/C22H27ClN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-
InChIKey	XPLJEFSRINKZLC-ATVHPVEESA-N

Chemical Details
Formal Charge	0
Atom Count	56
Chiral Atom Count	0
Bond Count	58
Aromatic Bond Count	11

Drug Info: DrugBank

DrugBank ID	DB08009 ?
Name	SU-11652
Groups	experimental
Description	SU-11652 is a tyrosine kinase inhibitor.
Synonyms	SU-11652
Categories	Heterocyclic Compounds, Fused-Ring
CAS number	326914-10-7

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Calcium/calmodulin-dependent protein kinase type 1G	MGRKEEDDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFA...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682