DrugBank ID DB00281 ? Name Lidocaine Groups Description Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication [T583]. In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical procedures [F4349, L5930, L5948]. It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding sensations [F4349, L5930, L5948]. In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. Nevertheless, lidocaine's local anesthetic action sees its use in many medical situations or circumstances that may benefit from its action, including the treatment of premature ejaculation [A177625]. Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis. It is even included in the World Health Organization's List of Essential Medicines [L6055]. Synonyms Lidocaine Lignocaine Lidocaine hydrochloride 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide 2-(Diethylamino)-2',6'-acetoxylidide
Lidocainum alpha-diethylamino-2,6-dimethylacetanilide Lidocaine hydrochloride anhydrous Lidocaina α-diethylamino-2,6-dimethylacetanilide Lidocaína more Brand Names Hydrocath Central Venous Catheter Kit Numb Zone Satohap Lidocaine 4% Menthol 1% Pain Relieving Cream Central Venous Catetherization Kit Naturally HL Extra Strength Hemorrhoid Numbing
De La Cruz Mercurochrome Zee First Aid Cream Xylocaine 2% Lidocanna Safetec Burn Gel Comfort EZ Extra StrengthTransdermal Patch Burn Relief Extra Strength Kool-Down ECOLAB Burn Harmony Neur Pain Relief Lignospan Forte Zee Blood Clotting Antiseptic Good Neighbor Pharmacy Burn Relief Aloe Extra Loxyine Lidocaine Plus Maximum Strength Pain Relieving Cream Lidoderm 5 Anorectal Equate Genuine First Aid Industrial First Aid Aramark Burn Cream Bottoms Up 50 Person ANSI Burn Relief Aloe Vera Gel GNP LidoFLEX Elbow, Single Pouch Lidozol Xylocaine Ointment 5% P-Care X 0.4% Lidocaine Hydrochloride and 5% Dextrose Injection USP KY Duration for Him 4022 First Aid Kit Fonow Lidocaine Hci and Dextrose Hyaluronic Acid 60mg and Lidocaine 2% PF Lidocaine Dry Patch Plus Menthol Anesthetic Odorless Analgesic Roll-on Meijer Lidocaine Hydrochloride Injection Lidocaine Hydrochloride Solution Bactine Max Dry Careland Lidocaine 4 Pain Relieving Gel-Patches Tattoo Numbing Cream HUMCO Mercuroclear GREEN GUARD Topical Pain Relief Aloe 4349 First Aid Kit GeriGentle FrostyHeat Pain Relief Patch 4 Lodocaine Back Prilo Patch-II Lidonexe Crane Safety Burn Burn with Lidocaine Curacaine Topcare Pain Relief Patches Xylocaine Dental Lidocaine HCl 2% and Epinephrine 1:100,000 EXTRA STRENGTH JOINT AND MUSCLE RELIEF 1500 mg Hemorrhoid Relief Cream Hot and Cold with Lidocaine-RA Pain Relieving Endurance Rx Male Desensitizer Inderma MD LiProZonePak Pliaglis 4100 First Aid Kit JUANCHI Tattoo Numbing Pain Relieving Lidocaine HCl Inj 20mg/ml First Aid Antiseptic Pain Relieving Lidocaine 4% Menthol 4% 4308 First Aid Kit Gabapal Sinsinpas Lidocaine Pain Relieving Bactine Original First Aid BonaDur Burn First Aid Microvix L Tylenol Precise Pain Relieving Chi-Myst Resolve Topical ReadySharp-P80 3 Step First Aid Kit Sunburn Pain Reliever CVS Noble Art Numbing Cream with Lidocaine HemAway Syren Intimate Pain Relief First Aid Burn Relief Rite Aid Lmx4 Lidocaine Patch Pain Relief Patches NATURES CRAFT LIDOCAINE Male Genital Desensitizer ASTONEA Burn Cream Meijer Cold and Hot Pain Relieving Analgesic ReadySharp-P40 CVS Cold and Hot Lidotral Five Percent DCH Burn Relief JO for Him Prolonger with Lidocaine Roosin Burn CBD Medic - Odor-Free Serious Relief 4348 First Aid Kit 4246 First Aid Kit BLUE ACME SLEEVE FIRST AID Contains 1000 PIECES Workvie Roll On 4295 First Aid Kit Atelocollagen Implant Zyvodol Walgreens 24-Hour Lidocaine Patch Synera Sole Serum Pure-Aid Nuvakaan WPR Plus Burn Relief Signature Care Res-Q Topical Analgesic Soothing Gel 4141 First Aid Kit Apicaine-X Extra Strength Shingle Chickenpox Relief Alivio Rite Aid Burn Relief Dentsply 2% Lidocaine With Epinephrine 1:100,000 AgonEaze Konicare 5% Vallement Flex Baciguent Plus Pain Reliever Ont GFA First Aid 16 Unit Metal Case Extra Strength Naturally Hl Sunburn Relief Icy Hot Lidocaine Dry Discount Drug Mart Pain Relief Patches Nervive Pain Relieving Liquid Roll-on First Aid Kit 64058024 Trubrexa Patch ER XYLOCAINE- MPF (LIDOCAINE HCl ) Numb Master Bed Bug Instant Bite Relief Bufferin Lidocaine Pain Numbing Totally Fun After Sun CBD Clinic - Mild Pain Therapy Itch Relief 4318 First Aid Kit P-Care 100MX Target Up and Up After Sun Cooling Bio-Scriptives Lidum 4271 First Aid Kit Base Laboratories Hemorrhoidal Aloe Ice Sunburn Relief Jelly 4258 First Aid Kit Xylocaine Oral Spray 4089 First Aid Kit 4198 First Aid Kit 4219 First Aid Kit CANNA NUMB Roll On Extra Strength Liquid Bedsore Relief Gel Lidocin 4261 First Aid Kit Diclovix Veltrix Lidocaine Hydrochloride Injection USP Bikini Zone Topical Analgesic Gel Diabetic First Aid Gel Lidosite Swabplus Piercing Care Swabs Will Relieve Roll-On Pain Relief Roll-on Good Sense First Aid Triple Antibiotic with Pain Reliever Xylocaine 0.5% W Epinephrine 1:200000 Dr Butlers Hemorrhoid and Fissure PF Jamshidi Bone Marrow Biopsy Tray Arthrogram Tray 1% TheraCare 4% Lidocaine Cream Lido GB-300 Walg Aftrsn Burn Relief Aspercreme Lidocaine Foot (Diabetic) Banana Boat Sooth-A-caine Spray Gel Up and Up Lidocaine Pain Relief Equate Pain Relieving Cream Lidocaine Extra Strength Postherpetic Neuralgia Relief First Aid Macimum Sterngth Bacitraycin Plus 4288 First Aid Kit Bactine Pain Relieving Caring Mills Relief Patch with Lidocaine Rite Aid Lidocaine Roll on Curist Lidocaine Maximum Strength Remaxazon External Patch Ebsl-5 Pain Relief Lidocaine Cutiecaine-5% LidaFlex TopCare Pain Relief Patch Maximum Strenght Lidocaine plus Menthol Pain Relief Patch Numb Soothe 4204 First Aid Kit Prilopentin PainGo KFT Lidocaine 5% Patch 4311 First Aid Kit Green Compass Reduce Topical Pain Band Aid Antiseptic Cleansing Liquid Doctor Butlers Hemorrhoid and Fissure External Pain Formula Aerowound Blood Clotting First Aid 4103 First Aid Kit 4032 First Aid Kit Dexlido-M Kit CBD4 pain relief cream Lidozen Gel Priloxx LP External Kit Benzalkonium Chloride and Lidocaine Hydrochloride Xylocaine Mpf 1.5% With Epinephrine Healerz for Noses Expanded Multi-med Kit Xylonor Spray AUVON LIDOCAINE MENTHOL Pain Relief Extra Strength Scar Prevention Lidocaine Hydrochloride and Dextrose LidoHeal-90 4079 First Aid Kit Walgreens Aloe Vera Pain Relieving Pacing Catheter Introducer Kit Acp-001px CVS Pain Relieving First Aid Antiseptic Maximum strength Lidocaine Patch 4337 First Aid Kit Releevia LM Patch 4228 First Aid Kit Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% GelAzul Roll-On Mlk F4-C TheraCare Maximum Strength Pain Relief Patch Instant Burn Relief Aloe Extra CVS 4117 First Aid Kit Polysporin Plus Pain Relief Lidocaine Patch, 5% TLC Plus Anesthetic G Lidopril XR Numbify Sanitize Lidocaine Pain Relieving 4220 First Aid Kit Ozonol Antibiotic Plus Ont Numb Gel Anesthetic Hempvana Ultra Strength Pain Relief Cream - Night JTT Physicians Joint, Tunnel and Trigger Topicaine Yowch for insect bites and stings by Pain Balm Coralite Odor Free Pain Relief Dentsply 2% Lidocaine With Epinephrine 1:50,000 Numb Nuts Rite Aid 4363 First Aid Kit Fruit of the Earth Sun Town City Amniocentesis Tray 1% Lidocaine and Menthol Hemorrhoidal-Ointment Xylocaine MPF OKeeffes Working Hands Pain Relief Skin Protectant Amazon Basics Pain Relief Patch with 4% Lidocaine BL-Contrast Alcoholada Gel Pain Relieving Pain Smartshield After Sun Uber Numb First Aid and Burn The Davinci Company Rapid Pain-relief Topical Stud 100 2677 First Aid Burn Cream Foster and Thrive BlueStop Max Medolor Pak Lidocaine and Prilocaine Cream Kit Advanced Seal Barrier plus Pain Relief First Aid Antiseptic Rite Aid pharmacy Blue Gel Anesthetic Numbing Max Strength Adellina TATTOO NUMBING LidoFLEX Lidozen Patch Pain Relief Patch 4194 First Aid Kit 4284 First Aid Kit 4269 First Aid Kit Octocaine HCl 2% Epinephrine 1:100000 Lidocaine 5% Arrow Central Venous Catheterization Kit Burn Relief Gel Lidocaine4 ANORECTAL Lidocaine Cream StaphAseptic OKeeffes Healthy Feet eLenza Patch Lidocaine Hci and Epinephrine With Epinephrine Res-Q Analgesic Topical Pain Relief Spray Lidocaine HCl Topical Solution Scar Zone Burn Gel Lidocaine Pain Relief Gel Patch Numbing Cream Banana Boat Sooth-A-caine W.moist.aloe V.gel 4365 First Aid Kit Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces Sunmed Motion Anestacon VacuStim Silver Lidocaine and Tetracaine Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) 4196 First Aid Kit SkyaDerm-LP Band-Aid Brand Hurt-Free Antiseptic Wash 4272 First Aid Kit SmartRx Gaba Kit 4379 First Aid Kit Lidozo Topical Pain Patch ReadySharp-K 4166 First Aid Kit DermaRad Relief Post Radiation Calming 4200 First Aid Kit 4374 First Aid Kit FAK Care4 Bus and School Yellow ORM D 4128 First Aid Kit Xylocaine Topical 5% 4116 First Aid Kit Nanonumb Eclipse Topical Anesthetic Maxocaine Pain Relieving Roll-ON Plush anesthetics L Extra Strength Naturally HL Foot Care Pain Gel Pain Relieving Cleansing Spray Medicated Pain Relief Foot CVS Lidocan Extra Strength Wound Care Genuine First Aid First Aid Antiseptic Pain Relieving Cream Lidocaine 4% Patch Lidocare 03 Hustle Helper Comfort Enhancing Anesthetic Antimicrobial Wash Lidenzal 1% Triderma Pain Relief Polysporin Cold Sore Ointment HealthWise Pain Relief Cream with Lidocaine Tylenol Precise Cooling Pain Relieving Bruselix Gel 4107 First Aid Kit LidoSport Pain Relief Patch Hempvana Pain Relief Zylotrol-L Blue-Emu Lidocaine Pain Relief Cream Dyural 80 LM-C HealthWise Lidocaine and Menthol Pain Relief PRILOVIX UltraLite Mentholatum Lidocaine Heat Liquid Sex GOOD NEIGHBOR PHARMACY FIRST AID Contains 202 PIECES Antibiotic Free Wound Gel and Pain Relief 4395 First Aid Kit QC Cool and Heat Roll-On D-Care 100X Burn Relief CVS GFA First Aid 75 Person Metal Case Kroger Pain Relief Lidocaine Patch Lidocaine 2% and Epinephrine 1:50,000 XYLOCAIN (LIDOCAINE HCl ) Xylocaine -MPF Harmony Hemp NeuroComfort Pain Relief Gel 500 Rite Aid Pain Relief Cream with Lidocaine 4335 First Aid Kit Pro-C-Dure 1 Kit Dexlido M-C DermacinRx DPN Pak Medi-quik First Aid Spray Albertsons Pain 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ARC FIRST AID Emergency Preparedness Contains 167 PIECES DermacinRx Cinlone-II CPI Equate Lidocaine Cool and Heat JOINT AND MUSCLE RELIEF 450 mg Lidocaine Hydrochloride Injection USP 0.5% FIRST AID Contains 303 PIECES Topical Anesthetic Anorectal Cream Numb and Number 4150 First Aid Kit BurnZone Burn Relief Continuous After Sun Soothing Spray Atozcup Tattoo Numbing Salonpas Pain Relieving LIDOCAINE 4% FLEX Lidopro Polysporin for Stitches 4066 First Aid Kit Lidovix L Spinal Anaesthesia Tray 4097 First Aid Kit Dologesic Roll-On Lidoderm Hemorrhoidal CLIN-LIDO-Single Use Kit SECONDARY NUMB Lidocaine Phenylephrine Gel Base Laboratories Base Numb Extra Strength Topical Anorectal LMR Plus DG health Harmony Hemp NeuroComfort Pain Relief Lotion500 Super Magic Man Premium Gold Family Medic First Aid Treatment - Liq Aramark Burn Electrum Numb Foam 4083 First Aid Kit LeedFrost Cream (lidocaine 5%) Aloe Ice Sunburn Relief Xylocaine 1% RectaGel HC Aprizio Pak CBD Pain Patches Fast Freeze Lidocaine Roll-On HealthWise Lidocaine Pain relief Vpmax Bikini Zone Medicated CREME Wegmans Aloe After Sun Gel with Lidocaine HCl External Analgesic Gigi Anesthetic Numbing Bakers Best Maximum Strength Pain Relief Chi-Myst Synergy Topical Doctor Butler Hemorrhoid and Fissure Advanced Formula HEM-EASY RELIEF Herbal Hemorrhoidal 4108 First Aid Kit Meijer Lidocaine Pain Relief Patch Assortment Small INTIMALE Maximum Strength Delay Hyronan LIDOCAINE HCl AND EPINEPHRINE Burn Relief Cream Lidocaine 3% Topical Anesthetic Cream K-Mart SmartSense First Aid Contains 101 Pieces 4208 First Aid Kit ACME FIRST AID Contains 404 PIECES Comfort EZ Pain Relief Patch Absorbine jr. 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77 Pieces Dyve Comfort L First Aid Burn Cream Rediburn Burn Gel Skin Protectant 4236 First Aid Kit Neurozyl Lidocaine Numbing Cream 4280 First Aid Kit Lumbar Puncture Tray 1% Insta Relief DM Xylocaine 2% Epidural FIRST AID Contains 1000 PIECES 4144 First Aid Kit Lidocaine Ointment USP, 5% Lidocaine 0.2% In 5% Dextrose Inj 4283 First Aid Kit Unburn-gel 2.5% Pain Relieving Cleansing Lidocaine Hydrochloride Serum X Acunistat-30 RX300 Topical Pain Cream Pain Cream Aflexeryl-LC more Indication Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks [F4349, L5930]. Categories Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use Agents that reduce seizure threshold Amides Amines Analgesics and Anesthetics
Anesthetics Anesthetics for Topical Use Anesthetics, Local Anilides Aniline Compounds Antiarrhythmic agents Antiarrhythmics, Class I Antiarrhythmics, Class Ib Antipruritics and Local Anesthetics Antipruritics, Incl. Antihistamines, Anesthetics, Etc. Cardiac Therapy Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (moderate) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2A6 Substrates Cytochrome P-450 CYP2B6 Substrates Cytochrome P-450 CYP2C18 Substrates Cytochrome P-450 CYP2C8 Substrates Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 CYP3A7 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dermatologicals Local Anesthesia Local Anesthetics (Amide) Membrane Transport Modulators Methemoglobinemia Associated Agents Nervous System Neuraxial Anesthetics Ophthalmologicals Otologicals P-glycoprotein inhibitors Peripheral Nervous System Agents Sensory System Agents Sodium Channel Blockers Throat Preparations Vasoprotectives Voltage-Gated Sodium Channel Blockers more ATC-Code S01HA07 D04AB01 R02AD02 C01BB01 S02DA01
N01BB52 C05AD01 N01BB02 more CAS number 137-58-6 
