MTA

5'-DEOXY-5'-METHYLTHIOADENOSINE

Find entries where: MTA

is present as a standalone ligand in 117 entries

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Chemical Component Summary
Name	5'-DEOXY-5'-METHYLTHIOADENOSINE
Identifiers	(2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol
Formula	C₁₁ H₁₅ N₅ O₃ S
Molecular Weight	297.334
Type	NON-POLYMER
Isomeric SMILES	CSC[C@@H]1[C@H]([C@H]([C@@H](O1)n2cnc3c2ncnc3N)O)O
InChI	InChI=1S/C11H15N5O3S/c1-20-2-5-7(17)8(18)11(19-5)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1
InChIKey	WUUGFSXJNOTRMR-IOSLPCCCSA-N

Chemical Details
Formal Charge	0
Atom Count	35
Chiral Atom Count	4
Bond Count	37
Aromatic Bond Count	10

Drug Info: DrugBank

DrugBank ID	DB02282 ?
Name	5'-S-methyl-5'-thioadenosine
Groups	experimental
Synonyms	5'-Methylthioadenosine 5-Methylthioadenosine 5'-Deoxy-5'-(methylthio)adenosine MTA 9-(5-S-methyl-5-thio-β-D-ribofuranosyl)-9H-purin-6-amine Methylthioadenosine Thiomethyladenosine S-Methyl-5'-thioadenosine 5'-S-methyl-5'-thioadenosine Vitamin L2
Categories	Amino Acids Amino Acids, Acidic Amino Acids, Dicarboxylic Amino Acids, Peptides, and Proteins Anti-Infective Agents Antineoplastic Agents Antiparasitic Agents Antiprotozoals Deoxyribonucleosides Enzyme Inhibitors Folic Acid Antagonists Glutamates Heterocyclic Compounds, Fused-Ring Nucleic Acid Synthesis Inhibitors Nucleic Acids, Nucleotides, and Nucleosides Nucleosides Protein O-Methyltransferase, antagonists & inhibitors Purine Nucleosides Purines Purinones Sulfur Compounds Xanthine derivatives
CAS number	2457-80-9

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Modification methylase RsrI	MANRSHHNAGHRAMNALRKSGQKHSSESQLGSSEIGTTRHVYDVCDCLDT...	unknown
S-methyl-5'-thioadenosine phosphorylase	MASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKI...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682