NDP
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Find entries where: NDP
is present as a standalone ligand in 1,124 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 16 entries
Chemical Component Summary | |
|---|---|
| Name | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE |
| Identifiers | [[(2R,3S,4R,5R)-5-(3-aminocarbonyl-4H-pyridin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate |
| Formula | C21 H30 N7 O17 P3 |
| Molecular Weight | 745.421 |
| Type | NON-POLYMER |
| Isomeric SMILES | c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)O[P@@](=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N |
| InChI | InChI=1S/C21H30N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 |
| InChIKey | ACFIXJIJDZMPPO-NNYOXOHSSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 78 |
| Chiral Atom Count | 10 |
| Bond Count | 82 |
| Aromatic Bond Count | 10 |
Drug Info: DrugBank
| DrugBank ID | DB02338? |
|---|---|
| Name | NADPH |
| Groups | experimental |
| Synonyms |
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| Categories |
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| CAS number | 53-57-6 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Thioredoxin reductase 1, cytoplasmic | MGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTST... | unknown | |
| Glucose-6-phosphate 1-dehydrogenase | MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQAL... | unknown | |
| Pteridine reductase 1 | MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSAT... | unknown | |
| Glucose--fructose oxidoreductase | MTNKISSSDNLSNAVSATDDNASRTPNLTRRALVGGGVGLAAAGALASGL... | unknown | |
| Dihydropyrimidine dehydrogenase [NADP(+)] | MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCF... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 134821689, 5884 |
| ChEMBL | CHEMBL407009 |
| ChEBI | CHEBI:16474 |
