NOJ

1-DEOXYNOJIRIMYCIN

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is present as a standalone ligand in 24 entries

is present in a branched oligosaccharide 6 entries

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Chemical Component Summary
Name	1-DEOXYNOJIRIMYCIN
Synonyms	MORANOLINE
Identifiers	(2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol
Formula	C₆ H₁₃ N O₄
Molecular Weight	163.172
Type	D-SACCHARIDE
Isomeric SMILES	C1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O
InChI	InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
InChIKey	LXBIFEVIBLOUGU-JGWLITMVSA-N

Chemical Details
Formal Charge	0
Atom Count	24
Chiral Atom Count	4
Bond Count	24
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB03206 ?
Name	Duvoglustat
Groups	investigational
Description	An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Synonyms	1-deoxy-nojirimycin 1-deoxynojirimycin 1,5-dideoxy-1,5-imino-D-glucitol Duvoglustat DNJ 1 deoxynojirimycin Deoxynojirimycin 1,5-deoxy-1,5-imino-D-mannitol (+)-1-Deoxynojirimycin Duvoglustat hydrochloride D-1-deoxynojirimycin 5-amino-1,5-dideoxy-D-glucopyranose
Categories	Alkaloids Amino Sugars Anti-Infective Agents Carbohydrates Enzyme Inhibitors Hexosamines Imines Imino Pyranoses Imino Sugars Piperidines
CAS number	19130-96-2

Drug Targets

Name	Target Sequence	Pharmacological Action
Cyclomaltodextrin glucanotransferase	MKRFMKLTAVWTLWLSLTLGLLSPVHAAPDTSVSNKQNFSTDVIYQIFTD...	unknown
Beta-glucosidase A	MNVKKFPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGNVKNGDT...	unknown
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	MAACEGRRSGALGSSQSDFLTPPVGGAPWAVATTVVMYPPPPPPPHRDFI...	unknown
Mannosyl-oligosaccharide alpha-1,2-mannosidase	MRLPVSFPLTVLSLLGSTIAHPYGETEAVLRSEPKSNQAKADAVKEAFQH...	unknown
Xylose isomerase	MSVQPTPADHFTFGLWTVGWTGADPFGVATRKNLDPVEAVHKLAELGAYG...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682