NTM
QUINOLINIC ACID
Find entries where: NTM
is present as a standalone ligand in 11 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 1 entries
Chemical Component Summary | |
|---|---|
| Name | QUINOLINIC ACID |
| Identifiers | pyridine-2,3-dicarboxylic acid |
| Formula | C7 H5 N O4 |
| Molecular Weight | 167.119 |
| Type | NON-POLYMER |
| Isomeric SMILES | c1cc(c(nc1)C(=O)O)C(=O)O |
| InChI | InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12) |
| InChIKey | GJAWHXHKYYXBSV-UHFFFAOYSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 17 |
| Chiral Atom Count | 0 |
| Bond Count | 17 |
| Aromatic Bond Count | 6 |
Drug Info: DrugBank
| DrugBank ID | DB01796? |
|---|---|
| Name | Quinolinic Acid |
| Groups | experimental |
| Description | A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. [PubChem] |
| Synonyms | Quinolinic Acid |
| Categories |
|
| CAS number | 89-00-9 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Nicotinate-nucleotide pyrophosphorylase [carboxylating] | MPPRRYNPDDRRDALLERINLDIPAAVAQALREDLGGEVDAGNDITAQLL... | unknown | |
| Nicotinate-nucleotide pyrophosphorylase [carboxylating] | MGLSDWELAAARAAIARGLDEDLRYGPDVTTLATVPASATTTASLVTREA... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL286204 |
| PubChem | 1066 |
| ChEMBL | CHEMBL286204 |
| ChEBI | CHEBI:16675 |
| CCDC/CSD | MEHFOV |
