ORN
L-ornithine
Find entries where: ORN
is present as a standalone ligand in 47 entries
is present in a polymer sequence 109 entries
Chemical Component Summary | |
|---|---|
| Name | L-ornithine |
| Identifiers | (2S)-2,5-bis(azanyl)pentanoic acid |
| Formula | C5 H12 N2 O2 |
| Molecular Weight | 132.161 |
| Type | L-PEPTIDE LINKING |
| Isomeric SMILES | C(C[C@@H](C(=O)O)N)CN |
| InChI | InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1 |
| InChIKey | AHLPHDHHMVZTML-BYPYZUCNSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 21 |
| Chiral Atom Count | 1 |
| Bond Count | 20 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB00129? |
|---|---|
| Name | Ornithine |
| Groups |
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| Description | Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine. |
| Synonyms |
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| Brand Names |
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| Indication | Used for nutritional supplementation, also for treating dietary shortage or imbalance. It has been claimed that ornithine improves athletic performance, has anabolic effects, has wound-healing effects, and is immuno-enhancing. |
| Categories |
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| ATC-Code | A05BA06 |
| CAS number | 70-26-8 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Ornithine aminotransferase, mitochondrial | MFSKLAHLQRFAVLSRGVHSSVASATSVATKKTVQGPPTSDDIFEREYKY... | unknown | |
| Ornithine carbamoyltransferase, mitochondrial | MLFNLRILLNNAAFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTG... | unknown | |
| Arginase-1 | MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDY... | unknown | |
| Ornithine decarboxylase antizyme 1 | MVKSSLQRILNSHCFAREKEGDKPSATIHASRTMPLLSLHSRGGSSSESS... | unknown | |
| High affinity cationic amino acid transporter 1 | MGCKVLLNIGQQMLRRKVVDCSREETRLSRCLNTFDLVALGVGSTLGAGV... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 88747248, 6262 |
| ChEMBL | CHEMBL446143 |
| ChEBI | CHEBI:15729 |
| CCDC/CSD | BAPKOV, HIWJIJ, BEZQOO, GOTFAY, DAHMAB, EVIJAU, BAPKIP, EMENUG, BIHYEX, EMENEQ, TEFMIA, ORNBDL10, BAPKUB |
