P48
N,1,4,4-TETRAMETHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE
Find entries where: P48
is present as a standalone ligand in 3 entries
Chemical Component Summary | |
|---|---|
| Name | N,1,4,4-TETRAMETHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE |
| Identifiers | N,1,4,4-tetramethyl-8-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-5H-pyrazolo[4,5-h]quinazoline-3-carboxamide |
| Formula | C25 H32 N8 O |
| Molecular Weight | 460.575 |
| Type | NON-POLYMER |
| Isomeric SMILES | CC1(Cc2cnc(nc2-c3c1c(nn3C)C(=O)NC)Nc4ccc(cc4)N5CCN(CC5)C)C |
| InChI | InChI=1S/C25H32N8O/c1-25(2)14-16-15-27-24(29-20(16)22-19(25)21(23(34)26-3)30-32(22)5)28-17-6-8-18(9-7-17)33-12-10-31(4)11-13-33/h6-9,15H,10-14H2,1-5H3,(H,26,34)(H,27,28,29) |
| InChIKey | RXZMYLDMFYNEIM-UHFFFAOYSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 66 |
| Chiral Atom Count | 0 |
| Bond Count | 70 |
| Aromatic Bond Count | 18 |
Drug Info: DrugBank
| DrugBank ID | DB16232? |
|---|---|
| Name | Milciclib Maleate |
| Groups | investigational |
| Description | Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy). |
| Synonyms |
|
| Categories | Heterocyclic Compounds, Fused-Ring |
| CAS number | 802539-81-7 |
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL564829 |
| PubChem | 16718576 |
| ChEMBL | CHEMBL564829 |
