PP2
1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE
Find entries where: PP2
is present as a standalone ligand in 5 entries
Chemical Component Summary | |
|---|---|
| Name | 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE |
| Identifiers | 1-tert-butyl-3-(4-chlorophenyl)pyrazolo[4,5-e]pyrimidin-2-ium-4-amine |
| Formula | C15 H17 Cl N5 |
| Molecular Weight | 302.782 |
| Type | NON-POLYMER |
| Isomeric SMILES | CC(C)(C)n1c2c(c([nH+]1)c3ccc(cc3)Cl)c(ncn2)N |
| InChI | InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19)/p+1 |
| InChIKey | PBBRWFOVCUAONR-UHFFFAOYSA-O |
Chemical Details | |
|---|---|
| Formal Charge | 1 |
| Atom Count | 38 |
| Chiral Atom Count | 0 |
| Bond Count | 40 |
| Aromatic Bond Count | 17 |
Drug Info: DrugBank
| DrugBank ID | DB03023? |
|---|---|
| Name | 1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine |
| Groups | experimental |
| Synonyms | 1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Tyrosine-protein kinase Lyn | MGCIKSKGKDSLSDDGVDLKTQPVRNTERTIYVRDPTSNKQQRPVPESQL... | unknown | |
| Proto-oncogene tyrosine-protein kinase Src | MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGP... | unknown | |
| Tyrosine-protein kinase Lck | MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVT... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
