TCK/PRD_000459

Tosyl-L-lysine chloromethyl ketone

TCK/PRD_000459 is described in the Biologically Interesting Molecule Reference Dictionary (BIRD).

The representative PDB ID is 4PAD.

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Chemical Component Summary
Name	Tosyl-L-lysine chloromethyl ketone
Synonyms	Tos-Lys-CH2Cl
Identifiers	N-[(3S)-7-azanyl-1-chloro-2-oxo-heptan-3-yl]-4-methyl-benzenesulfonamide
Formula	C₁₄ H₂₁ Cl N₂ O₃ S
Molecular Weight	332.846
Type	PEPTIDE-LIKE
Isomeric SMILES	Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl
InChI	InChI=1S/C14H21ClN2O3S/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16/h5-8,13,17H,2-4,9-10,16H2,1H3/t13-/m0/s1
InChIKey	RDFCSSHDJSZMTQ-ZDUSSCGKSA-N
Composition	Polymer Sequences: TSU-LYS-0QE
BIRD class	INHIBITOR
Represented As	SINGLE MOLECULE
Compound Details	n/a
Description	n/a

Chemical Details
Formal Charge	0
Atom Count	42
Chiral Atom Count	1
Bond Count	42
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB08603 ?
Name	N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide
Groups	experimental
Synonyms	N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Protease 1	MKRICGSLLLLGLSISAALAAPASRPAAFDYANLSSVDKVALRTMPAVDV...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682