PRF

7-DEAZA-7-AMINOMETHYL-GUANINE

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is present as a standalone ligand in 30 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 2 entries

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Chemical Component Summary
Name	7-DEAZA-7-AMINOMETHYL-GUANINE
Identifiers	2-amino-5-(aminomethyl)-3,7-dihydropyrrolo[3,2-e]pyrimidin-4-one
Formula	C₇ H₉ N₅ O
Molecular Weight	179.179
Type	NON-POLYMER
Isomeric SMILES	c1c(c2c([nH]1)N=C(NC2=O)N)CN
InChI	InChI=1S/C7H9N5O/c8-1-3-2-10-5-4(3)6(13)12-7(9)11-5/h2H,1,8H2,(H4,9,10,11,12,13)
InChIKey	MEYMBLGOKYDGLZ-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	22
Chiral Atom Count	0
Bond Count	23
Aromatic Bond Count	5

Drug Info: DrugBank

DrugBank ID	DB03304 ?
Name	7-Deaza-7-Aminomethyl-Guanine
Groups	experimental
Synonyms	7-Deaza-7-Aminomethyl-Guanine

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Queuine tRNA-ribosyltransferase	MVEATAQETDRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAAT...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682